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Rhinopithecus roxellana (golden snub-nosed monkey): 104665700
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Entry
104665700 CDS
T03989
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01521
EGFR tyrosine kinase inhibitor resistance
rro04062
Chemokine signaling pathway
rro04148
Efferocytosis
rro04151
PI3K-Akt signaling pathway
rro04217
Necroptosis
rro04550
Signaling pathways regulating pluripotency of stem cells
rro04630
JAK-STAT signaling pathway
rro04658
Th1 and Th2 cell differentiation
rro04659
Th17 cell differentiation
rro04725
Cholinergic synapse
rro04917
Prolactin signaling pathway
rro04920
Adipocytokine signaling pathway
rro04933
AGE-RAGE signaling pathway in diabetic complications
rro04935
Growth hormone synthesis, secretion and action
rro05140
Leishmaniasis
rro05145
Toxoplasmosis
rro05152
Tuberculosis
rro05161
Hepatitis B
rro05164
Influenza A
rro05167
Kaposi sarcoma-associated herpesvirus infection
rro05168
Herpes simplex virus 1 infection
rro05200
Pathways in cancer
rro05207
Chemical carcinogenesis - receptor activation
rro05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
104665700 (JAK2)
04151 PI3K-Akt signaling pathway
104665700 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
104665700 (JAK2)
09143 Cell growth and death
04217 Necroptosis
104665700 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
104665700 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
104665700 (JAK2)
04659 Th17 cell differentiation
104665700 (JAK2)
04062 Chemokine signaling pathway
104665700 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
104665700 (JAK2)
04917 Prolactin signaling pathway
104665700 (JAK2)
04935 Growth hormone synthesis, secretion and action
104665700 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
104665700 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104665700 (JAK2)
05207 Chemical carcinogenesis - receptor activation
104665700 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
104665700 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
104665700 (JAK2)
05164 Influenza A
104665700 (JAK2)
05168 Herpes simplex virus 1 infection
104665700 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
104665700 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
104665700 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
104665700 (JAK2)
05140 Leishmaniasis
104665700 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
104665700 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
104665700 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
104665700 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rro01001
]
104665700 (JAK2)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
104665700 (JAK2)
Protein kinases [BR:
rro01001
]
Non-receptor tyrosine kinases
JAK family [OT]
104665700 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
104665700
NCBI-ProteinID:
XP_030775231
LinkDB
All DBs
Position
16:56277575..56441922
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEY
VAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPR
WYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMA
VLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFNSLKDLLNCYQ
METVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
KLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMH
FLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYMIMTECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcctgccttactatgacagaaatggagggaacatccacatcttctatatatcagaat
ggtgatatttctggaaatgccaattctatgaagcaaatagatccagtccttcaggtgtat
ctttaccattcccttgggaaatctgaggcagattatctgacctttccatctggggagtat
gttgcagaagaaatctgtattgctgcttctaaagcttgtggtatcacacctgtgtatcat
aatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccatgtcttc
catatagatgagtcaaccaggcataatgtactctacagaataagattttattttcctcgt
tggtattgcagcggcagcaacagagcctatcggcatggaatatctcgaggtgctgaagct
cctcttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgattttgtg
catggatggataaaagtacccgtgactcatgaaacacaggaagaatgtcttgggatggca
gtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactggccatctataac
tctatcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagactatcat
attttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttcagccaa
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaccctgcag
tctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgcgattttcctaat
attattgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccgagttgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagct
ttgtctttcgtgtcattaattgatgggtattatagattaactgcagatgcacatcattac
ctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgtcatggc
ccaatttcgatggattttgccattagtaaactgaagaaagcaggtaatcagactggactg
tatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgctgtcgag
cgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaagagtac
aacctcagtgggacaaagaagaacttcaacagtcttaaagatcttttgaattgttaccag
atggaaaccgttcgctcagacaatataattttccagtttactaagtgctgtcccccaaag
ccaaaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgtaccaacc
tcaccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatatttaatgaaagccttggccaaggcacttttacaaagatttttaaaggc
atacgaagagaagtaggagactatggtcaactgcatgaaacagaagttcttttaaaagtt
ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
aagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaagaataaa
aattgtataaatatattgtggaaacttgaagttgcaaaacagttggcatgggccatgcat
tttctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattctacttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataaacctctaagtgctctggattctcaaagaaag
ctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaattagcaaac
cttataaataattgtatggattatgagccagatttcaggccttctttcagagccatcata
cgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcctttgaagacagggatcctaca
cagtttgaagagagacatttgaaatttctacagcaactcggcaagggtaattttgggagt
gtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggctgtaaaa
aagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaaatcctg
aaatccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactatcttcaa
aaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatatgcaag
ggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagaaatata
ttggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctggtatgcc
ccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtg
gttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaatttatg
cgtatgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaacttttg
aagaataatggaagattaccaagaccagatggatgcccagatgagatttatatgatcatg
acagaatgctggaacaataatgtaaatctgcgcccctcctttagagatttagctcttcga
gtggatcaaataagggataacatggctggatga
DBGET
integrated database retrieval system
