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Suncus etruscus (white-toothed pygmy shrew): 126009984
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Entry
126009984 CDS
T09902
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr01521
EGFR tyrosine kinase inhibitor resistance
setr04062
Chemokine signaling pathway
setr04148
Efferocytosis
setr04151
PI3K-Akt signaling pathway
setr04217
Necroptosis
setr04550
Signaling pathways regulating pluripotency of stem cells
setr04630
JAK-STAT signaling pathway
setr04658
Th1 and Th2 cell differentiation
setr04659
Th17 cell differentiation
setr04725
Cholinergic synapse
setr04917
Prolactin signaling pathway
setr04920
Adipocytokine signaling pathway
setr04933
AGE-RAGE signaling pathway in diabetic complications
setr04935
Growth hormone synthesis, secretion and action
setr05140
Leishmaniasis
setr05145
Toxoplasmosis
setr05152
Tuberculosis
setr05161
Hepatitis B
setr05164
Influenza A
setr05167
Kaposi sarcoma-associated herpesvirus infection
setr05168
Herpes simplex virus 1 infection
setr05200
Pathways in cancer
setr05207
Chemical carcinogenesis - receptor activation
setr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
setr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
126009984 (JAK2)
04151 PI3K-Akt signaling pathway
126009984 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
126009984 (JAK2)
09143 Cell growth and death
04217 Necroptosis
126009984 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
126009984 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
126009984 (JAK2)
04659 Th17 cell differentiation
126009984 (JAK2)
04062 Chemokine signaling pathway
126009984 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
126009984 (JAK2)
04917 Prolactin signaling pathway
126009984 (JAK2)
04935 Growth hormone synthesis, secretion and action
126009984 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
126009984 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
126009984 (JAK2)
05207 Chemical carcinogenesis - receptor activation
126009984 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
126009984 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
126009984 (JAK2)
05164 Influenza A
126009984 (JAK2)
05168 Herpes simplex virus 1 infection
126009984 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
126009984 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
126009984 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
126009984 (JAK2)
05140 Leishmaniasis
126009984 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
126009984 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
126009984 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
126009984 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
setr01001
]
126009984 (JAK2)
Enzymes [BR:
setr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
126009984 (JAK2)
Protein kinases [BR:
setr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
126009984 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
Kinase-like
RIO1
Motif
Other DBs
NCBI-GeneID:
126009984
NCBI-ProteinID:
XP_049630218
LinkDB
All DBs
Position
1:complement(65219507..65380595)
Genome browser
AA seq
1131 aa
AA seq
DB search
MGMACLTMTEMEETSLPIHQNGNIPGNANTVTQIDPVLQVYLYHSLGKAEGDYLKFPTGE
YVAEEICIAASKACGITPVYHSMFALMNETERIWYPPNHVFHIDESVGHNVLYRIRFYFP
YWYCNGSNRTYRHGISRGAEVPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGM
AVLDMMRIAKEKDQTPLDVYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFS
QCKATARNLKLKYLINLETLQSGFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRG
KHKESETLKEQDLQLYCDFPDIIDVSIKQASQESSNESRIVTIHKQDGKNLEIELLSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTG
LYVLRCSPKDFNKYFLTFAVERENVTEYKHCLITKNENGEYNLTGTKKNFNNLKDLLNCY
QMETVRSDSIIFQFTKCCPPRPKDKSNLLVFRTNGVSDVPISPTLQRHNNVNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLYETEVLLKILDKAHRNYSESFFEAASMM
SQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAM
HFLEEKLLTHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELA
NLINNCMDYEADFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKDRIDHKRLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENETRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY
APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
LKNNGRLPRPDGCPDEIYMIMTECWNNNVNHRPSFRDLALRVDQIRDNMTG
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaagaaacatcattacctatacatcag
aatggtaatattcctggcaacgctaatactgtgacacaaatagatccagttttacaagtg
tatctttatcactcgcttgggaaagctgagggagattacttgaagtttccaactggggaa
tatgttgctgaagaaatttgtattgctgcttctaaagcttgtggaattacccctgtgtat
cacagtatgtttgctttaatgaatgaaactgaaaggatctggtatccacctaatcatgtc
ttccatatagatgaatcagtggggcacaatgtactctacaggataagattttacttccca
tactggtattgtaatggcagcaacagaacctatcgacatggaatatctcgaggtgctgaa
gttcctcttcttgatgattttgtcatgtcttaccttttcgctcagtggcgacatgatttt
gtgcatggatggatcaaagtacccgtgactcatgaaacacaggaagaatgtcttggcatg
gcagtgttagatatgatgagaatagccaaagaaaaagatcaaactccactggatgtctat
aactctatcagctacaagacttttttaccaaaatgtgtgcgagcaaagattcaagactat
catattttgacaaggaagcgaataaggtatagatttagaagatttattcagcagttcagc
cagtgcaaagccactgccagaaacttgaaacttaagtatcttataaatttggaaactctt
cagtctggcttctacacagaacaatttgaagtaaaagaaccgggaagaggtccttcaggt
gaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagaggg
aaacataaagaaagtgagacactgaaagaacaggatttacagttatattgtgattttcct
gatattattgatgtcagtattaaacaggcaagccaagaaagctcaaatgaaagcagaatt
gtaactatccataagcaagatgggaaaaatctggaaattgaactactttcactaagagaa
gctttgtcctttgtgtcattaattgatggatattatagattaactgcagatgcacatcat
tatctttgtaaggaagttgcacctccaatggttcttgagaatatacaaagcaactgtcat
ggcccaatttcaatggattttgccatcagtaaactgaagaaagcaggtaatcagactgga
ctatatgtacttcgctgcagtcctaaggattttaataaatattttttgactttcgctgtt
gagagagaaaatgtcactgaatacaagcattgcttgattaccaaaaatgaaaatggagaa
tacaaccttactggtactaaaaagaacttcaataatcttaaagatcttttgaattgctac
cagatggaaactgttcgctcagatagtataattttccagtttactaaatgttgccctcca
aggccaaaagataaatcaaatcttctagtcttcagaaccaatggtgtttctgatgtacca
atctcaccaacattgcaaagacataataatgttaaccaaatggtatttcataaaatcaga
aatgaagatttgatatttaatgaaagtcttggccaaggcacttttacaaaaatttttaaa
ggtgtaagaagagaagtgggagactatggtcagctgtatgaaacagaagttcttttgaaa
attctggataaagcacatagaaattattcagagtctttctttgaagcagcaagcatgatg
agccaactttctcataagcatctggttttaaattatggagtatgtgtttgtggagaggag
aatatccttgttcaggagtttgtaaaatttggatcactagatacttatttgaagaagaat
aaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggccatg
cattttctagaagaaaaactccttactcatgggaatgtgtgtgccaaaaatattctactt
attagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggc
attagtattacagttttgcctaaggacattcttcaggagagaataccatgggtaccacct
gaatgcattgaaaatcctaaaaatttaaacttggcaacagataaatggagttttggtacc
actttgtgggaaatctgcagtggaggagataaacctctcagtgctctggattctcaaaga
aagctacagttttatgaagataggcaccaactccctgcaccaaaatggacagaactagca
aatcttattaataattgtatggactatgaagcagattttagaccttctttcagagccata
atacgagatcttaatagtttgtttacaccagattatgaattattaacagaaaatgacatg
ctgccaaatatgcgcataggtgccttagggttttctggtgcttttgaagaccgtgatcct
acacaatttgaagagagacatttgaaatttttacaacaacttggcaagggaaattttgga
agtgtggaaatgtgccgctatgaccccttacaagacaatactggtgaggtggtggctgtg
aagaaactccagcacagcactgaagagcacctcagagactttgaaagggaaatcgaaatc
cttaaatccctgcagcatgacaacattgtaaagtacaagggagtatgttacagtgctggc
cggcgtaatctaagattaattatggaatatttgccatatggaagtttacgagactatctc
caaaaacataaagaccgtatagatcataaaagacttctgcagtatacatcccagatatgc
aagggcatggagtatcttggtacaaaaaggtatattcacagggatctggcaacaaggaat
atattggtggagaatgaaaccagagttaaaataggagattttggtttaacaaaggtctta
ccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtat
gctccagaatcactgacagagagcaagttttctgtagcatcagatgtttggagctttgga
gtagttctatatgagctttttacttatattgagaaaagtaaaagtccaccagcggaattt
atgcgtatgataggtaatgacaagcaaggacagatgattgtgtttcatttgatagaactc
ctaaagaataatgggagattaccaaggcctgatggatgccctgatgagatttacatgatc
atgacagaatgctggaacaataatgtaaatcaccgcccctctttcagagacctagctctt
cgagttgatcaaataagggacaatatgactggatga
DBGET
integrated database retrieval system