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Zalophus californianus (California sea lion): 113934060
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Entry
113934060 CDS
T07874
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01521
EGFR tyrosine kinase inhibitor resistance
zca04062
Chemokine signaling pathway
zca04148
Efferocytosis
zca04151
PI3K-Akt signaling pathway
zca04217
Necroptosis
zca04550
Signaling pathways regulating pluripotency of stem cells
zca04630
JAK-STAT signaling pathway
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca04725
Cholinergic synapse
zca04917
Prolactin signaling pathway
zca04920
Adipocytokine signaling pathway
zca04933
AGE-RAGE signaling pathway in diabetic complications
zca04935
Growth hormone synthesis, secretion and action
zca05140
Leishmaniasis
zca05145
Toxoplasmosis
zca05152
Tuberculosis
zca05161
Hepatitis B
zca05164
Influenza A
zca05167
Kaposi sarcoma-associated herpesvirus infection
zca05168
Herpes simplex virus 1 infection
zca05200
Pathways in cancer
zca05207
Chemical carcinogenesis - receptor activation
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
113934060 (JAK2)
04151 PI3K-Akt signaling pathway
113934060 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113934060 (JAK2)
09143 Cell growth and death
04217 Necroptosis
113934060 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
113934060 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
113934060 (JAK2)
04659 Th17 cell differentiation
113934060 (JAK2)
04062 Chemokine signaling pathway
113934060 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
113934060 (JAK2)
04917 Prolactin signaling pathway
113934060 (JAK2)
04935 Growth hormone synthesis, secretion and action
113934060 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
113934060 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113934060 (JAK2)
05207 Chemical carcinogenesis - receptor activation
113934060 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113934060 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
113934060 (JAK2)
05164 Influenza A
113934060 (JAK2)
05168 Herpes simplex virus 1 infection
113934060 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
113934060 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
113934060 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
113934060 (JAK2)
05140 Leishmaniasis
113934060 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113934060 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
113934060 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113934060 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113934060 (JAK2)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113934060 (JAK2)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
113934060 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
113934060
NCBI-ProteinID:
XP_027470389
UniProt:
A0A6J2EN51
LinkDB
All DBs
Position
13:89002748..89149757
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSVSPVQQNGDIPGNANPVKQIDPLLQVYLYHSLEKAEGEYLKFPTGEY
VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESARHNVLYRIRFYFPY
WYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLGMA
VLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLEALQSAFYTEQFEVKEPGRGPSGEEIFATVIITGNGGIQWSRGK
HKESETLAEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELCSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNCYQ
METVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKIRN
EDLVFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggaacatccgtatctcctgtacaacagaat
ggtgatattcctggaaacgcgaatcccgtgaagcaaatagatccactcctacaggtgtat
ctttatcattctcttgagaaagccgaaggagagtatctgaagtttccaactggggagtat
gttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtgtatcat
agtatgtttgctttaatgagtgaaacagaaaggatttggtatccgcccaaccatgtcttc
catatagatgaatcagccaggcacaatgtactctacagaataagattttactttccttac
tggtattgtaatggcagcaacagaacctatcggcatgggatatctcgaggtgctgaagct
cctcttcttgacgactttgtcatggcctacctttttgctcagtggcggcatgatttttta
catggatggataaaaatacccgtgacccatgaaacacaggaagaatgtcttggaatggct
gtgttagatatgatgagactagccaaagagaaggatcaaaccccactggacatctatagc
tctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagactatcat
attttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaagctcttcag
tctgccttctacacagagcagtttgaagtaaaagaacctggaagagggccttcaggtgag
gagatttttgcaaccgttataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagactctggcagaacaggatttacagttatattgtgactttcctgat
attattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtagaattgta
actatccataagcaagatggtaaaaatctggaaattgaactttgctcattaagagaagct
ttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacatcattac
ctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgtcatggc
ccaattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagactggactc
tatgtacttcgatgcagtcctaaggactttaataagtattttctgacttttgctgtagag
cgagaaaatgtcatcgaatataagcactgtttgattacaaaaaatgagaatggagaatac
aacctcagtggtaccaagaagaacttcagtaatcttaaagatcttttgaattgctaccaa
atggaaactgttcgctcagacagtataattttccagtttactaaatgctgccccccaaag
ttgaaagataaatcaaaccttctagtcttcagaaccaatggcgtttctgatgttccaaca
tcaccaacattacaaaggcataataatgtgaaccaaatggtgtttcacaaaatcagaaat
gaagatttggtgtttaatgaaagccttggtcaaggcacttttacaaaaatttttaaaggt
ataagaagagaagtaggagactatggtcaactacatgaaacagaagttctgttaaaagtt
ctggataaagcgcacagaaactattcagagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaagcatctagttttaaattatggagtatgtgtctgtggggaagagaat
attctggttcaagagttcgtaaaatttggatcactagatacatatctgaaaaagaataaa
aattctataaatatattatggaaacttgaagtggctaaacagttggcatgggccatgcat
tttctagaagaaaaagcacttattcatgggaatgtgtgtgccaaaaatattctgcttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaagcttagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcatcgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggtaccacc
ttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaaagaaag
ctacagttttatgaagataagcaccagcttcctgcaccaaagtggacagaattagcaaat
cttattaataattgtatggattatgaaccagattttaggccttctttcagagccatcata
cgagatcttaatagtttgtttactccagattatgaactattaacagagaatgacatgtta
ccaaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagaccctaca
cagtttgaagagagacacttgaaatttctacagcaacttggtaagggtaattttggcagt
gtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggctgtgaag
aagctccagcatagtactgaggagcacctgagagactttgagagggaaattgaaatcctt
aaatccctgcagcatgacaacattgtgaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaagattaattatggaatatttaccatatggaagtttacgagactatctccaa
aaacataaagaacggatagatcataaaaaacttctgcagtatacatctcagatatgcaag
ggcatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaggaatata
ttggtagaaaacgaaaacagggttaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttggagtg
gttctgtatgaacttttcacatatattgagaagagtaaaagtcccccagcggaatttatg
cgtatgattggcaatgacaaacaaggacagatgattgtctttcatttgatagaactccta
aagaataatggaagattaccaagaccagatggatgtccagatgagatttatttgatcatg
acagaatgctggaacaataatgtcaatcaacgcccctcttttagagacctagctcttcga
gttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system