"Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates" was published in Cell, a Cell Press journal, on Sept 4. USAMRIID authors included co-first authors Eric Mucker and Sandra Bixler and co-corresponding author Jay Hooper as well as several other personnel from USAMRIID’s Virology, Diagnostics Systems, and Pathology Divisions. Considering the ongoing clade 2 mpox epidemic and rapidly expanding clade 1 outbreak, this work is timely because it provides information on how a gene-based vaccine might perform relative to the MVA-based vaccine that is currently being used to address what the World Health Organization (WHO) has declared a global public health emergency. The mRNA vaccine not only protected nonhuman primates from lethal mpox, it also greatly reduced lesion (pocks) number, viremia, and virus shedding as measured by throat swabs. Combined, these findings indicate the mRNA vaccine might be more effective at preventing disease transmission, although this has not been demonstrated experimentally. The mpox mRNA vaccine, dubbed mRNA-1760, builds on historic gene-based vaccine research conducted at USAMRIID and The National Institutes of Health (NIH), and the mRNA vaccine development and systems serology expertise of Moderna. This vaccine, if fully developed, could contribute to the arsenal of medical countermeasures designed to protect the warfighter for the threat posed by mpox and other orthopox viruses. mRNA-1760, is currently in a phase 1/2 clinical trial. https://lnkd.in/dn-8RES8 #mpox l #InfectiousDiseases l #scientificresearch l #research l #vaccine Telemedicine & Advanced Technology Research Center - TATRC U. S. Army Aeromedical Research Laboratory - USAARL (Official) U.S. Army Medical Materiel Development Activity Walter Reed Army Institute of Research Defense Threat Reduction Agency Defense Health Agency Military Health System
USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases
Research Services
Frederick, Maryland 6,189 followers
Biodefense solutions to protect our nation
About us
Since 1969, USAMRIID has provided leading edge medical capabilities to deter and defend against current and emerging biological threat agents. The Institute is the only laboratory in the Department of Defense equipped to safely study highly hazardous viruses requiring maximum containment at Biosafety Level 4. Research conducted at USAMRIID leads to vaccines, drugs, diagnostics, and training programs that protect both Warfighters and civilians. The Institute's unique science and technology base serves not only to address current threats to our Armed Forces but is an essential element in the medical response to any future biological threats that may confront our nation.
- Website
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https://usamriid.health.mil/
External link for USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases
- Industry
- Research Services
- Company size
- 501-1,000 employees
- Headquarters
- Frederick, Maryland
- Type
- Government Agency
- Founded
- 1969
Locations
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Primary
1425 Porter Street
Frederick, Maryland 21702, US
Employees at USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases
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Deborah Coates
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Rafael O Torres Cruz
Lieutenant Commander at United States Public Health Service
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Nick Kumar, PMP
CTO, IT Program Manager | Cloud-based Database Technologies, PMP, MD Real Estate Broker
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Ondraya Frick
Research Microbiologist/COR, US Army Medical Research Institute of Infectious Diseases
Updates
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We couldn’t have said it better ourselves. Congratulations SSG Comiskey and thank you for all of the hard work and care you bring to the team! #StayArmy | #RIIDrockstar | U.S. Army Medical Research and Development Command | Defense Health Agency |
Today, I attended the reenlistment ceremony of SSG Comiskey. He is the NCOIC of our Division of Medicine. He is one of the most outgoing SSG of Soldiers I have encountered at #USAMRIID. He mentors, he leads, he ensures morale is good, and he also serves with enthusiasm and passion. Part of his packet guarantees his next duty assignment as an Instructor at Fort Sam Houston. I’m proud to have known him and watxh him grow as a leader. He will excel at the schoolhouse and the Army is lucky to have him. Congratulations SSG Comiskey!!!!
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The Diagnostic Readiness Adaptive Global Operational Network & Mobile Embedded Diagnostic Capability (DRAGON MEDIC) is designed to allow procurement, RDT&E and/or operations and maintenance funds to be used for full life cycle of technology development, acquisition and upgrades, allowing the Department of Defense to harness rapidly evolving technologies. DRAGON MEDIC ensures the joint and Service acquisition pipelines can keep pace with the rapid advancement of technology and the evolving threat from emerging infectious diseases and biological warfare agents. This process can help combat the introduction of unknown biological threats to the force, whether intentional or natural, preventing major risk to mission through overwhelming loss of combat power. The USAMRIID team designed a “push-pull” relationship with field forward laboratories to field iterative prototype diagnostic technology, driving down risk and receiving feedback with near parallel development and fielding. The current pilot is with the 1ST Area Medical Laboratory with targeted and untargeted sequencing (Far Forward Advanced Sequencing Technology/FFAST). The targeted sequencing capability was fielded to the 1st AML as an iterative protype. 1ST AM was able to demonstrate the capability in April 2024 during a joint mobile lab workshop with the CARA (20th CBRNE) and the Polish Army. They correctly identified RNA targets in complex biological matrices in under 10 minutes of sequencing. The DRAGON MEDIC won the 2024 MG Harold “Harry” Greene Award for Innovation.
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The USAMRIID Vector Threat Assessment Branch is currently testing the efficacy of the permethrin-treated Army Combat Uniform (ACU) for protecting the Soldiers against vector-borne diseases. The test is being conducted using infected (infected with vaccine strain chikungunya virus, CHIKV 181/25) and uninfected Aedes aegypti mosquitoes over 0, 10, and 25 washes of the ACU. U.S. Army Medical Research and Development Command | Defense Health Agency | #bugborneillness | #Chikungunya | #Westnilevirus | #EasternEquineEncephalitis |
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#mhsrs2024 has begun! Our #USAMRIID team is on ground to network, learn and share for the advancement of medical and scientific research and development. Come see us at booth 621! U.S. Army Medical Research and Development Command | Defense Health Agency | Telemedicine & Advanced Technology Research Center - TATRC | USAMRICD | #mhsrs2024 | #research | #Biodefense |
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MHSRS is the Department of Defense’s premier scientific meeting focused on the unique medical needs of the Warfighter. USAMRIID will be present to showcase exciting research and how it can be applied across the globe. This is an excellent way to connect with military medical professionals, U.S. Department of Defense (DoD) scientists, industry experts and more to discuss cutting-edge research. See you there! #MHSRS2024 #MilitaryResearch #USAMRIID Defense Health Agency U.S. Army Medical Research and Development Command
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Branch Chief, Viral Pathogenesis at USAMRIID , US Army Medical Research Institute of Infectious Diseases
Do you have a desire to contribute to protecting the Warfighter against entomological threats? Check out our opportunity below. We’re looking for a recent PhD graduate with a passion for vector borne disease research. https://lnkd.in/dzuud__s
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Our Budget department took some time to celebrate Taylar Dowling and her future #RIIDKid! It is rare to be able to hold a baby shower, so they jumped at the chance to support their teammate. Congrats Taylar! #USAMRIID | #Team | #RIIDFamily | U.S. Army Medical Research and Development Command |
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Our #RIIDrockstars are out traveling to conventions and keeping the #Biodefense community up-to-date on all of the amazing work happening at RIID. Bill Dorman and Capt. Elizabeth Babcock recently presented “Laboratory Identification of Biological Warfare Agents” to over 130 attendees at the annual Society for American Federal Medical Laboratory Scientists symposium. SGT Louis Henrick also presented a poster on “Establishment of Performance Specifications Validation Report for a Monkeypox Virus Clade I Real time PCR assay of the QuantStudio Dx Analyzer.” The conference had over 750 registered attendees. #USAMRIID | #SAFMLS | U.S. Army Medical Research and Development Command | Defense Health Agency |
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USAMRIID — U.S. Army Medical Research Institute of Infectious Diseases reposted this
Registration is now open for the 2024 Military Health System Research Symposium! Join us August 26-29 at the Gaylord Palms Resort in Kissimmee, FL. Connect with military medical professionals, United States Department of Defense scientists, industry experts and more to discuss cutting-edge research. Register now: http://www.mhsrs.net/ #MHSRS2024 | #MilitaryResearch | #MilitaryMedicine