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LOC103189738 complement C4-A [ Callorhinchus milii (elephant shark) ]

Gene ID: 103189738, updated on 7-Dec-2023

Summary

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Gene symbol
LOC103189738
Gene description
complement C4-A
See related
Ensembl:ENSCMIG00000004611 Ensembl:ENSCMIG00000006489
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinchus milii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
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Genomic context

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See LOC103189738 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
41
Annotation release Status Assembly Chr Location
101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704771.1 (2447503..2491979, complement)
100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890349.1 (339929..370983)

NW_024704771.1Genomic Context describing neighboring genes Neighboring gene hepatocyte cell adhesion molecule-like Neighboring gene tapasin-like Neighboring gene uncharacterized LOC103189736 Neighboring gene uncharacterized LOC121851191

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elephant shark genome provides unique insights into gnathostome evolution. Venkatesh B, et al. Nature, 2014 Jan 9. PMID 24402279, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement C4-A
Names
complement C4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference IMCB_Cmil_1.0 Primary Assembly

Genomic

  1. NW_024704771.1 Reference IMCB_Cmil_1.0 Primary Assembly

    Range
    2447503..2491979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042344796.1 → XP_042200730.1  complement C4-A

    UniProtKB/TrEMBL
    V9K886
    Conserved Domains (4) summary
    COG2373
    Location:126 → 1091
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd00017
    Location:665 → 724
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    cd02896
    Location:968 → 1273
    complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
    cl02512
    Location:1531 → 1625
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
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