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jak2a Janus kinase 2a [ Hippocampus comes (tiger tail seahorse) ]

Gene ID: 109517077, updated on 11-Apr-2024

Summary

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Gene symbol
jak2a
Gene description
Janus kinase 2a
See related
Ensembl:ENSHCOG00000003063
Gene type
protein coding
RefSeq status
MODEL
Organism
Hippocampus comes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Syngnathiaria; Syngnathiformes; Syngnathoidei; Syngnathidae; Hippocampus
Also known as
jak2
Orthologs
zebrafish all
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Genomic context

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See jak2a in Genome Data Viewer
Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current H_comes_QL1_v1 (GCF_001891065.1) Unplaced Scaffold NW_017805372.1 (421414..435743, complement)

NW_017805372.1Genomic Context describing neighboring genes Neighboring gene plasminogen receptor, C-terminal lysine transmembrane protein Neighboring gene relaxin 1 Neighboring gene ring finger and CCCH-type domains 2 Neighboring gene RAB GTPase activating protein 1 Neighboring gene probable G-protein coupled receptor 21

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017805372.1 Unplaced Scaffold Reference H_comes_QL1_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK2
Names
Janus kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hippocampus comes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference H_comes_QL1_v1 Primary Assembly

Genomic

  1. NW_017805372.1 Reference H_comes_QL1_v1 Primary Assembly

    Range
    421414..435743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019872000.1 → XP_019727559.1  tyrosine-protein kinase JAK2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2XD04
    Related
    ENSHCOP00000001963.1, ENSHCOT00000011209.1
    Conserved Domains (4) summary
    smart00295
    Location:39 → 219
    B41; Band 4.1 homologues
    cl15255
    Location:380 → 476
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:270 → 380
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:835 → 1118
    PKc_like; Protein Kinases, catalytic domain

  2. XM_019871998.1 → XP_019727557.1  tyrosine-protein kinase JAK2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2XD04
    Conserved Domains (4) summary
    smart00295
    Location:39 → 219
    B41; Band 4.1 homologues
    cl15255
    Location:380 → 476
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:270 → 380
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:835 → 1118
    PKc_like; Protein Kinases, catalytic domain

  3. XM_019872001.1 → XP_019727560.1  tyrosine-protein kinase JAK2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2XD04
    Conserved Domains (4) summary
    cl09511
    Location:10 → 129
    FERM_B-lobe; FERM domain B-lobe
    cl15255
    Location:290 → 386
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:180 → 290
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:745 → 1028
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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