Abstract
Leishmania donovani is considered the causative organism of visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL). Testing of 4/29 DNA samples from VL and PKDL patients as well as 2/7 field isolates showed an aberrant internal transcribed spacer 1 (ITS1) restriction fragment length polymorphism (RFLP) pattern, which upon sequencing strongly matched Leptomonas seymouri, thus confirming its presence in Indian leishmaniasis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Base Sequence
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Child
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Child, Preschool
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Cluster Analysis
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Coinfection / diagnosis*
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Coinfection / parasitology
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DNA, Protozoan / chemistry
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DNA, Protozoan / genetics
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DNA, Ribosomal Spacer / chemistry
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DNA, Ribosomal Spacer / genetics
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Euglenozoa Infections / complications*
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Euglenozoa Infections / diagnosis*
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Euglenozoa Infections / parasitology
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Female
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Humans
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India
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Infant
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Leishmania donovani / isolation & purification*
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Leishmaniasis / complications*
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Leishmaniasis / diagnosis*
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Leishmaniasis / parasitology
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Male
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Middle Aged
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Molecular Sequence Data
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Phylogeny
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Sequence Alignment
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Sequence Analysis, DNA
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Trypanosomatina / isolation & purification*
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Young Adult
Substances
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DNA, Protozoan
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DNA, Ribosomal Spacer