Transfusion-transmitted hepatitis E in a misleading context of autoimmunity and drug-induced toxicity

Stéphanie Haïm-Boukobza; Marie-Pierre Ferey; Anne-Laure Vétillard; Asma Jeblaoui; Elisabeth Pélissier; Gilles Pelletier; Laurent Teillet; Anne-Marie Roque-Afonso

doi:10.1016/j.jhep.2012.08.001

Transfusion-transmitted hepatitis E in a misleading context of autoimmunity and drug-induced toxicity

J Hepatol. 2012 Dec;57(6):1374-8. doi: 10.1016/j.jhep.2012.08.001. Epub 2012 Aug 8.

Authors

Stéphanie Haïm-Boukobza¹, Marie-Pierre Ferey, Anne-Laure Vétillard, Asma Jeblaoui, Elisabeth Pélissier, Gilles Pelletier, Laurent Teillet, Anne-Marie Roque-Afonso

Affiliation

¹ National Reference Center for Hepatitis A and E, APHP, Paul Brousse Hospital, Department of Virology, Villejuif, France.

PMID: 22885386
DOI: 10.1016/j.jhep.2012.08.001

Abstract

Hepatitis E is currently diagnosed after all other causes of hepatitis have been excluded. Moreover, HEV testing is not performed to prevent blood transmission in developed countries. We report here on the case of a patient with acute hepatitis while receiving potentially hepatotoxic medications for autoimmune disorders, with low-level autoimmune markers and negative "standard" viral markers; it was finally determined that he was suffering from transfusion-transmitted hepatitis E.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Autoimmune Diseases / drug therapy*
Chemical and Drug Induced Liver Injury / etiology*
Female
Hepatitis E / etiology*
Hepatitis E / transmission
Humans
Male
Middle Aged
Transfusion Reaction*