Single Academic Center Experience of Unrestricted β-d-Glucan Implementation

Valeria Fabre; Theodore Markou; Kathryn DeMallie; Seema Mehta; Shmuel Shoham; Pranita D Tamma; Sean Zhang; Sara E Cosgrove

doi:10.1093/ofid/ofy195

Single Academic Center Experience of Unrestricted β-d-Glucan Implementation

Open Forum Infect Dis. 2018 Aug 9;5(9):ofy195. doi: 10.1093/ofid/ofy195. eCollection 2018 Sep.

Authors

Valeria Fabre¹, Theodore Markou¹, Kathryn DeMallie¹, Seema Mehta¹, Shmuel Shoham¹, Pranita D Tamma², Sean Zhang³, Sara E Cosgrove¹

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
² Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
³ Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Abstract

We investigated serum β-d-glucan (BDG) testing among non-neutropenic adult inpatients at an academic center where the test is unrestricted. BDG orders were inappropriate in 49% of cases due to absence of predisposing host factors or clinical picture consistent with fungal infection. Providers' knowledge about BDG was insufficient.

Keywords: fungal infection; implementation; β-D-glucan.