Aging News and Research

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Enzyme blockade improves memory updating in older mice

Everyone has moments of forgetfulness from time to time, especially as we get older. But older adults don't just have difficulty remembering new information.

9 Aug 2024

Violent dementia patients leave nursing home staffers and residents ‘scared to death’

Dan Shively had been a bank president who built floats for July Fourth parades in Cody, Wyoming, and adored fly-fishing with his sons.

9 Aug 2024

University of Michigan National Poll reveals 30% of adults in 50s and 60s are caregivers

More than 1 in 4 people age 50 and older help take care of at least one family member or friend who has a health issue or disability, according to new results from the University of Michigan National Poll on Healthy Aging.

9 Aug 2024

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain.

8 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Researchers at Columbia University Mailman School of Public Health, the University of North Carolina at Chapel Hill and at the National Academy of Sciences of Ukraine used the setting of the man-made Ukrainian Holodomor famine of 1932-1933 to examine the relation between prenatal famine and adult Type 2 diabetes mellitus (T2DM).

8 Aug 2024

Alcohol use disorders in parents linked to accelerated aging in children

Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have discovered that parents who struggle with alcohol use disorders can pass along symptoms of early aging to their children, affecting them well into adulthood.

8 Aug 2024

Research finds synaptic strength key to maintaining memory in old age

Over the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences.

7 Aug 2024

Study suggests lower dementia risk for people with Parkinson's

There's some good news for people with Parkinson's disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course of the disease than previously reported, according to a study published in the August 7, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

Study links internet exclusion to increased depression in older adults

Older adults excluded from the internet are at a higher risk of depressive symptoms, especially among the economically deprived and those with lower education levels. Addressing internet exclusion is crucial to improving mental health in this population.

7 Aug 2024

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Ecklonia cava polyphenols (ECPs) show promise in reducing neuronal damage caused by rotenone in Parkinson’s disease (PD) by activating the Nrf2-ARE pathway, highlighting their potential as a neuroprotective treatment.

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

High initial drug doses may reduce cancer drug resistance

On July 28, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center published a new editorial in Volume 16, Issue 14 of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), entitled, "Targeted cancer therapy: the initial high concentration may slow down the selection for resistance."

6 Aug 2024

Aging News and Research

Enzyme blockade improves memory updating in older mice

Violent dementia patients leave nursing home staffers and residents ‘scared to death’

University of Michigan National Poll reveals 30% of adults in 50s and 60s are caregivers

NIH awards $3.5M grant to study link between traumatic brain injury and Alzheimer's

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Alcohol use disorders in parents linked to accelerated aging in children

Research finds synaptic strength key to maintaining memory in old age

Study suggests lower dementia risk for people with Parkinson's

How C. elegans uses smell to preemptively guard against pathogen attacks

Study links internet exclusion to increased depression in older adults

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

High initial drug doses may reduce cancer drug resistance

Breakthrough therapy enhances longevity and vitality in aging mice

Survey: 30% of people in their 50s and 60s provide care to loved ones with health problems

Reduced folate intake enhances metabolic plasticity in aged mice

Menopause myths: Separating fact from fiction

Osteoporosis and aging linked at cellular level

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

A Discussion with Hologic’s Tim Simpson on the Future of Cervical Cancer Screening

From Waste to Taste: The Transformative Power of Fermented Foods

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