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American football head impacts tied to increased brain damage and cognitive decline

Repetitive head impacts in former American football players are linked to increased perivascular space volume, which correlates with cognitive decline and neurodegeneration. The study suggests that the force of head impacts may be more critical than frequency, with potential protective effects from β-blocker use.

1 Sep 2024

Routine lipoprotein(a) testing recommended for all adults

Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.

29 Aug 2024

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

The study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and plaque formation in arteries.

27 Aug 2024

Study reveals genetic link between Alzheimer's disease, lipid metabolism, and coronary artery disease

The genetic overlap between Alzheimer's disease (AD) (a neurodegenerative disorder causing memory loss and cognitive decline), lipid profiles, and coronary artery disease (CAD).

20 Aug 2024

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

The long-term subjective cognitive decline risk associated with Herpes zoster infections.

19 Aug 2024

Anti-inflammatory diets could lower dementia risk among older individuals with cardiometabolic disorders

Researchers investigated whether anti-inflammatory diets support cognitive functions among cardiometabolic disease (CMD) patients.

15 Aug 2024

Coronary atherosclerosis prevalent even in low-risk adults with normal cholesterol levels

Researchers found that coronary atherosclerosis is prevalent in asymptomatic, middle-aged US adults without traditional ASCVD risk factors, and increases with higher levels of LDL-C, non-HDL-C, and apoB.

8 Aug 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Ketogenic vs. low-sugar diet: Study reveals distinct metabolic effects and fat loss benefits

A ketogenic diet and reduced free sugar intake both lead to weight loss but have different effects on glucose tolerance, lipid metabolism, and the gut microbiome, with the ketogenic diet showing unfavorable metabolic changes.

7 Aug 2024

Omega-3 fatty acids show potential in protecting brain health in older adults

Researchers assess the role of ω-3 polyunsaturated fatty acids (PUFAs) in reducing white matter lesion accumulation and neuronal integrity degeneration.

6 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

New research reveals keto diet’s impact on cholesterol and gut microbiome

A study from the University of Bath reveals that ketogenic low-carbohydrate diets can increase cholesterol levels and reduce beneficial gut bacteria, specifically Bifidobacterium.

2 Aug 2024

Shorter exclusive breastfeeding periods for women with a higher BMI compared to those with lower obesity classifications

Researchers examined nursing behaviors and their relationships with maternal anthropometric factors and the serological metabolome six months after birth in ethnically diverse obese mothers.

31 Jul 2024

Study finds plasma biomarkers can predict dementia risk

A study in JAMA explores the potential of plasma biomarkers for Alzheimer’s disease and cardiometabolic risk factors to predict other types of dementia, highlighting the importance of early diagnosis and combining biomarkers with demographic data for improved accuracy.

30 Jul 2024

Apolipoprotein News and Research

American football head impacts tied to increased brain damage and cognitive decline

Routine lipoprotein(a) testing recommended for all adults

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

Study reveals genetic link between Alzheimer's disease, lipid metabolism, and coronary artery disease

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

Anti-inflammatory diets could lower dementia risk among older individuals with cardiometabolic disorders

Coronary atherosclerosis prevalent even in low-risk adults with normal cholesterol levels

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Ketogenic vs. low-sugar diet: Study reveals distinct metabolic effects and fat loss benefits

Omega-3 fatty acids show potential in protecting brain health in older adults

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

New research reveals keto diet’s impact on cholesterol and gut microbiome

Shorter exclusive breastfeeding periods for women with a higher BMI compared to those with lower obesity classifications

Study finds plasma biomarkers can predict dementia risk

Dementia risk rises with elevated remnant cholesterol, South Korean study reveals

Garlic as a potent weapon against atherosclerosis

Study finds body composition impacts neurodegenerative disease risk

Can cutting back on extra virgin olive oil make your heart healthier?

Associations between gut microbes and Alzheimer’s disease

Living near greenspace in midlife tied to slower cognitive decline in older age

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

A Discussion with Hologic’s Tim Simpson on the Future of Cervical Cancer Screening

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