Intracellular News and Research

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Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Ecklonia cava polyphenols (ECPs) show promise in reducing neuronal damage caused by rotenone in Parkinson’s disease (PD) by activating the Nrf2-ARE pathway, highlighting their potential as a neuroprotective treatment.

7 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Rapid, noninvasive tool tracks neurons and biomolecules activated in the brain by psychedelic drugs

Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs.

5 Aug 2024

Seaweed antioxidants show promise in preventing Parkinson's disease

Parkinson's disease is a neurodegenerative disease caused by the loss of neurons that produce dopamine, a neurotransmitter involved in motor control and cognitive function.

5 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

Revolutionary real-time microscopy unveils secrets of motor protein behavior

A team led by Professor Seo Dae-ha of the Department of Physics and Chemistry at DGIST (President Lee Kun-woo) has developed new real-time microscopy technology and successfully observed the behavior of "motor proteins", which may hold the key to unraveling the efficient material transport strategy of cells.

2 Aug 2024

Study provides novel insights into the molecular mechanisms of melanoma progression

Cong Peng et al., at Department of Dermatology, Xiangya Hospital, Central South University, China, conducted a study titled "NETO2 promotes melanoma progression via activation of the Ca²⁺/CaMKII signaling pathway" that investigates the role of Neuropilin and tolloid-like 2 (NETO2) in melanoma, a deadly form of skin cancer.

2 Aug 2024

Mast cells found to capture and employ neutrophils during allergic reactions

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system.

2 Aug 2024

Novel electrical impedance technique enhances drug testing for cardiac safety

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical.

1 Aug 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Researchers created a detailed transcriptomic atlas of six brain regions, revealing cell-type-specific and region-specific vulnerabilities in Alzheimer's disease and highlighting astrocyte genes linked to cognitive resilience.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

Creating the first genetically susceptible mice for late-onset Alzheimer's

Mice don't get Alzheimer's-;and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.

24 Jul 2024

Kaempferol's promise in fighting triple-negative breast cancer

Review highlights kaempferol's potential in treating triple-negative breast cancer through various anticancer mechanisms and improving chemotherapeutic efficacy.

24 Jul 2024

Dietary interventions improve mitochondrial function and reduce inflammation in obesity

Study demonstrates that dietary interventions such as calorie restriction, intermittent fasting, and ketogenic diet improve mitochondrial function in monocytes and reduce inflammation in obesity by modulating gut microbiota.

23 Jul 2024

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Breast cancer (BC) remains one of the most challenging cancers to treat, primarily due to its heterogeneity and propensity for metastasis.

23 Jul 2024

Revolutionary ATP imaging technique sheds light on kidney cell energy production

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

23 Jul 2024

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Drug repurposing shows promise in the treatment of retinal degenerations, according to a new study by an international team of researchers, published in Nature Communications.

22 Jul 2024

Understanding astrocyte-neuron interplay in learning deficits

In the brain, synaptic plasticity - the ability to change neuronal connections over time - is fundamental to learning and memory.

18 Jul 2024

Intracellular News and Research

Review of fasting-mimicking diets in cancer treatment

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Rapid, noninvasive tool tracks neurons and biomolecules activated in the brain by psychedelic drugs

Seaweed antioxidants show promise in preventing Parkinson's disease

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Revolutionary real-time microscopy unveils secrets of motor protein behavior

Study provides novel insights into the molecular mechanisms of melanoma progression

Mast cells found to capture and employ neutrophils during allergic reactions

Novel electrical impedance technique enhances drug testing for cardiac safety

ACE technology enhances single-cell protein detection with advanced signal amplification

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

Creating the first genetically susceptible mice for late-onset Alzheimer's

Kaempferol's promise in fighting triple-negative breast cancer

Dietary interventions improve mitochondrial function and reduce inflammation in obesity

Exploring non-coding RNAs as regulators of notch signaling in breast cancer

Revolutionary ATP imaging technique sheds light on kidney cell energy production

Combination therapy incorporating three existing drugs shows potential for treating retinal degenerations

Understanding astrocyte-neuron interplay in learning deficits

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

A Discussion with Hologic’s Tim Simpson on the Future of Cervical Cancer Screening

From Waste to Taste: The Transformative Power of Fermented Foods

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