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Dietary fiber intake reshapes tryptophan metabolism, promoting gut health and reducing disease risks

A recent study in Nature Microbiology reveals that increased dietary fiber intake directs microbial tryptophan metabolism, leading to health benefits such as improved gut mucosa integrity and reduced risk of metabolic disorders.

27 Jun 2024

Study identifies key neurons controlling threat response and escape in mice

Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic stress disorder (PTSD).

27 Jun 2024

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

Ovarian cancer, often diagnosed at an advanced stage, presents significant treatment challenges because patients tend to develop resistance to conventional therapies quickly.

26 Jun 2024

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation.

26 Jun 2024

Designing hybrid antibodies with enhanced mobility and signaling capacity

Antibodies are the body's superheroes, recognizing and eliminating disease-causing substances.

25 Jun 2024

Senecavirus A could be a promising new therapeutic approach for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a highly aggressive tumor with limited treatment options and high mortality.

25 Jun 2024

Sapio Sciences Introduces Sapio GMP LIMS Offering Unmatched Flexibility for Unique Manufacturing Processes

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From Sapio Sciences 25 Jun 2024

Chimpanzees seek out tree bark and ferns with medicinal benefits, researchers discover

Researchers investigated the behavioral and pharmacological effects of self-medicative plants in the diets of Budongo chimpanzees.

25 Jun 2024

Study links gene regulation to allergic airway inflammation

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.

25 Jun 2024

Using microbial community-scale metabolic modeling approach for precision nutrition

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.

24 Jun 2024

New study warns of potential pandemic risk from α-H1N2 swine flu virus

The α-H1N2 influenza virus in swine poses a higher pandemic risk due to its ability to evade human immunity and transmit between species, highlighting the need for vigilant monitoring.

23 Jun 2024

Novo Nordisk presents key findings from semaglutide trials at ADA scientific sessions 2024

Novo Nordisk today announced the presentation of 34 abstracts highlighting the breadth of its portfolio at the upcoming 84th Scientific Sessions of the American Diabetes Association (ADA).

22 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Study reveals cognitive benefits of ketogenic diet in aged mice

The impact of cyclic ketogenic diet treatments in improving the age-related decline in brain function.

20 Jun 2024

Iontronic technology shows promise in slowing malignant brain tumor growth

When low doses of cancer drugs are administered continuously near malignant brain tumors using so-called iontronic technology, cancer cell growth drastically decreases.

19 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

In an animal model of Duchenne muscular dystrophy, Brazilian researchers tested a therapy that combines photobiomodulation using laser light or light-emitting diodes (LEDs) with idebenone, an antioxidant compound investigated for application in neurodegenerative diseases.

14 Jun 2024

in vivo News and Research

Dietary fiber intake reshapes tryptophan metabolism, promoting gut health and reducing disease risks

Study identifies key neurons controlling threat response and escape in mice

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

Designing hybrid antibodies with enhanced mobility and signaling capacity

Senecavirus A could be a promising new therapeutic approach for hepatocellular carcinoma

Sapio Sciences Introduces Sapio GMP LIMS Offering Unmatched Flexibility for Unique Manufacturing Processes

Chimpanzees seek out tree bark and ferns with medicinal benefits, researchers discover

Study links gene regulation to allergic airway inflammation

Using microbial community-scale metabolic modeling approach for precision nutrition

New study warns of potential pandemic risk from α-H1N2 swine flu virus

Novo Nordisk presents key findings from semaglutide trials at ADA scientific sessions 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Study reveals cognitive benefits of ketogenic diet in aged mice

Iontronic technology shows promise in slowing malignant brain tumor growth

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

Study links balanced neural activity to enhanced cognitive abilities in youth

Deep learning revives ancient peptides to battle antibiotic resistance

Human antibodies show promise against Black widow spider venom

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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