PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-Co-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes
Version 1
: Received: 3 November 2018 / Approved: 5 November 2018 / Online: 5 November 2018 (08:48:52 CET)
How to cite:
Ismail, F. S.; Jamil, S. N. A. M.; Cormack, P. A. G.; Abdullah, L. C.; Kamaruzaman, S.; Daik, R. The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-Co-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes. Preprints2018, 2018110091. https://doi.org/10.20944/preprints201811.0091.v1
Ismail, F. S.; Jamil, S. N. A. M.; Cormack, P. A. G.; Abdullah, L. C.; Kamaruzaman, S.; Daik, R. The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-Co-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes. Preprints 2018, 2018110091. https://doi.org/10.20944/preprints201811.0091.v1
Ismail, F. S.; Jamil, S. N. A. M.; Cormack, P. A. G.; Abdullah, L. C.; Kamaruzaman, S.; Daik, R. The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-Co-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes. Preprints2018, 2018110091. https://doi.org/10.20944/preprints201811.0091.v1
APA Style
Ismail, F. S., Jamil, S. N. A. M., Cormack, P. A. G., Abdullah, L. C., Kamaruzaman, S., & Daik, R. (2018). The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-<em>Co</em>-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes. Preprints. https://doi.org/10.20944/preprints201811.0091.v1
Chicago/Turabian Style
Ismail, F. S., Sazlinda Kamaruzaman and Rusli Daik. 2018 "The Synthesis and Characterisations of Porous Thioamide-Sulfonated-Modified Poly (Acrylonitrile-<em>Co</em>-Divinylbenzene-80) as a Potential Sorbent to Capture Polar Analytes" Preprints. https://doi.org/10.20944/preprints201811.0091.v1
Abstract
Pharmaceuticals contain biologically active components that can pollute water courses as a result of the excretions from individuals and/or uncontrolled release of residues from chemical plants, and they can pose a hazard to health. Pharmaceutical residues can persist at low concentrations in the environment, and thus may be potentially harmful to aquatic animals and to humans. Controlling and monitoring such residues are therefore a prime interest, for example, a solid-phase extraction uses solid sorbents to purify and preconcentrate the residues prior to their chemical analysis. In the present study, poly (acrylonitrile-co-divinylbenzene-80) sorbents are synthesised by varying the comonomer feed ratios under precipitation polymerisation conditions to deliver a family of porous polymer microspheres. Acrylonitrile confers polar characters onto the sorbents, and the acrylonitrile-derived nitrile groups can be chemically transformed via polymer-analogous reactions into thioamide and sulfonated residues which make the sorbents even more suitable for the capture of polar analytes, including selected pharmaceuticals. The utility of the porous thioamide-sulfonated containing sorbents is demonstrated via the dispersion-solid phase extraction of mefenamic acid from aqueous media; mefenamic acid is an anthranilic acid derivative which is a potent, non-steroidal anti-inflammatory drug which is found in environmental waters at low concentrations.
Keywords
polyacrylonitrile; chemical modification; thiourea; polar pharmaceuticals; sulphonation; dispersion-solid phase extraction
Subject
Chemistry and Materials Science, Applied Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.