Bahos, F.A.; Sainz-Vidal, A.; Sánchez-Pérez, C.; Saniger, J.M.; Gràcia, I.; Saniger-Alba, M.M.; Matatagui, D. ZIF Nanocrystal-Based Surface Acoustic Wave (SAW) Electronic Nose to Detect Diabetes in Human Breath. Biosensors2019, 9, 4.
Bahos, F.A.; Sainz-Vidal, A.; Sánchez-Pérez, C.; Saniger, J.M.; Gràcia, I.; Saniger-Alba, M.M.; Matatagui, D. ZIF Nanocrystal-Based Surface Acoustic Wave (SAW) Electronic Nose to Detect Diabetes in Human Breath. Biosensors 2019, 9, 4.
Bahos, F.A.; Sainz-Vidal, A.; Sánchez-Pérez, C.; Saniger, J.M.; Gràcia, I.; Saniger-Alba, M.M.; Matatagui, D. ZIF Nanocrystal-Based Surface Acoustic Wave (SAW) Electronic Nose to Detect Diabetes in Human Breath. Biosensors2019, 9, 4.
Bahos, F.A.; Sainz-Vidal, A.; Sánchez-Pérez, C.; Saniger, J.M.; Gràcia, I.; Saniger-Alba, M.M.; Matatagui, D. ZIF Nanocrystal-Based Surface Acoustic Wave (SAW) Electronic Nose to Detect Diabetes in Human Breath. Biosensors 2019, 9, 4.
Abstract
In the present work a novel, portable and innovative eNose composed of a surface acoustic wave (SAW) sensor array based ZIF-8, and ZIF-67 nanocrystals (pure and combined with gold nanoparticles) as sensitive layers has been tested as a non-invasive system to detect and differentiate disease markers, such as acetone, ethanol and ammonia, related with early diagnosis of diabetes mellitus through exhaled breath. The sensors have been prepared by spin coating, achieving continuous and homogenous sensitive layers. Low concentrations (5 ppm, 10 ppm and 25ppm) of the marker analytes were measured, obtaining high sensitivities, good reproducibility, short time response and fast signal recovery.
Keywords
eNose; gas sensor, SAW; Surface Acoustic Wave, Love wave, diabetes, breath, VOC, ZIF, Zeolite
Subject
Medicine and Pharmacology, Other
Copyright:
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