Version 1
: Received: 14 April 2020 / Approved: 16 April 2020 / Online: 16 April 2020 (16:05:27 CEST)
How to cite:
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints2020, 2020040285. https://doi.org/10.20944/preprints202004.0285.v1
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints 2020, 2020040285. https://doi.org/10.20944/preprints202004.0285.v1
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints2020, 2020040285. https://doi.org/10.20944/preprints202004.0285.v1
APA Style
Raj, S., Chandel, V., Rathi, B., & Kumar, D. (2020). Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints. https://doi.org/10.20944/preprints202004.0285.v1
Chicago/Turabian Style
Raj, S., Brijesh Rathi and Dhruv Kumar. 2020 "Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach" Preprints. https://doi.org/10.20944/preprints202004.0285.v1
Abstract
In December 2019, outbreak of novel coronavirus (COVID-19) occurred in Wuhan, Hubei Province, China and exported across the world leading to thousands of deaths and millions of suspected cases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection into the host undergoes a huge number of complex replicative machineries which still remains unclear. Understanding the mechanism (s) of replication and mode of infection of SARS-CoV2 to human cells will help us in the development of novel vaccines or drugs for the eradication and prevention of the disease. This review compiles the knowledge of SARS-CoV2 replicative machinery, mode of infection to the human cells and the development of drugs and vaccines which are currently under clinical trials.
Medicine and Pharmacology, Pulmonary and Respiratory Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.