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Preprint Short Note Version 1 Preserved in Portico This version is not peer-reviewed

(R)-(+)-3,5-dinitro-N-(1-phenylethyl)benzothioamide

Version 1 : Received: 24 April 2023 / Approved: 25 April 2023 / Online: 25 April 2023 (04:18:23 CEST)

A peer-reviewed article of this Preprint also exists.

Donahue, M.G.; Crull, E. (R)-(+)-3,5-Dinitro-N-(1-phenylethyl)benzothioamide. Molbank 2023, 2023, M1650. Donahue, M.G.; Crull, E. (R)-(+)-3,5-Dinitro-N-(1-phenylethyl)benzothioamide. Molbank 2023, 2023, M1650.

Abstract

(R)-(+)-3,5-Dinitro-N-(1-phenylethyl)benzothioamide 1 is a potential chiral solvating agent (CSA) for the spectral resolution of enantiomers by 1H NMR spectroscopy. The single enantiomer of 1 was synthesized from commercially (R)-(+)-a-methylbenzylamine 2 in two-steps with 85% yield.

Keywords

benzylamine; chiral solvating agent; thioamide

Subject

Chemistry and Materials Science, Organic Chemistry

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