Gabriele, B.; Mancuso, R.; Della Ca’, N.; Veltri, L.; Ziccarelli, I. An Overview of Catalytic Carbonylative Double Cyclization Reactions. Catalysts2023, 13, 1025.
Gabriele, B.; Mancuso, R.; Della Ca’, N.; Veltri, L.; Ziccarelli, I. An Overview of Catalytic Carbonylative Double Cyclization Reactions. Catalysts 2023, 13, 1025.
Gabriele, B.; Mancuso, R.; Della Ca’, N.; Veltri, L.; Ziccarelli, I. An Overview of Catalytic Carbonylative Double Cyclization Reactions. Catalysts2023, 13, 1025.
Gabriele, B.; Mancuso, R.; Della Ca’, N.; Veltri, L.; Ziccarelli, I. An Overview of Catalytic Carbonylative Double Cyclization Reactions. Catalysts 2023, 13, 1025.
Abstract
This short review is aimed at giving an overview of catalytic carbonylative double cyclization reactions, which are processes in which suitable organic substrates and carbon monoxide are sequentially activated by a promoting catalyst to afford the formation of two new cycles with concomitant incorporation of carbon monoxide as a carbonyl function into the final product. Paradigmatic examples of this powerful synthetic methodology, which allows the one-step synthesis of complex molecular architectures from simple building blocks using the simplest and readily available C-1 unit (CO) are illustrated and discussed. The review is divided into five sections: 1) Introduction; 2) Functionalized Olefinic Substrates; 3) Functionalized Acetylenic Substrates; 4) Functionalized Halides; 5) Conclusions and Future Perspectives.
Chemistry and Materials Science, Organic Chemistry
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