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Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox
Version 1
: Received: 13 August 2023 / Approved: 14 August 2023 / Online: 14 August 2023 (07:14:36 CEST)
How to cite:
Zhang, Q.; Cao, Z.; Zhang, K. Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints2023, 2023080984. https://doi.org/10.20944/preprints202308.0984.v1
Zhang, Q.; Cao, Z.; Zhang, K. Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints 2023, 2023080984. https://doi.org/10.20944/preprints202308.0984.v1
Zhang, Q.; Cao, Z.; Zhang, K. Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints2023, 2023080984. https://doi.org/10.20944/preprints202308.0984.v1
APA Style
Zhang, Q., Cao, Z., & Zhang, K. (2023). <strong></strong>Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints. https://doi.org/10.20944/preprints202308.0984.v1
Chicago/Turabian Style
Zhang, Q., Zhimin Cao and Kai Zhang. 2023 "<strong></strong>Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox" Preprints. https://doi.org/10.20944/preprints202308.0984.v1
Abstract
Objective: To examine the effect of bilateral total lobectomy and unilateral total lobectomy on improving thyroid function in patients with thyroid micropapillary carcinomatreated with euthyrox. Methods: The study was conducted on 68 patients with thyroid micro papillary carcinoma treated with euthyroxwho had been surgically treated with euthyrox in our hospital between January 2018 and December 2019. On the basis of random number grouping, they were divided into control groups (n = 34, bilateral total lobectomy) and observation groups (n = 34, unilateral total lobectomy plus isthmectomy). Thyroid function, free triiodothyronine (FT3), thyroid hormone (TSH), and voice function (VHI score) of the two groups were compared.Results: In comparison to the control group, the observation group had shorter incision lengths, shorter operation times, and shorter hospital stays, as well as less intraoperative bleeding and drainage volume, and the difference was statistically significant (P < 0.05); As compared with the control group, the observation group had higher FT4 and FT3 levels as well as lower TSH levels, a statistically significant difference (P < 0.05).VHI scores of emotions, function, physiology, and other voice functions were significantly lower among the observation group than those of the control group (P < 0.05).Conclusion: A unilateral total lobectomy with adjacent isthmus resection in patients with thyroid micro papillary carcinoma can yield ideal results, accelerate the time taken for surgical rehabilitation, improve thyroid function, thereby improving voice quality, as well as improve the overall prognosis of the patient.
Keywords
Thyroid papillary carcinoma; Bilateral total lobectomy; Unilateral total lobectomy plus isthmectomy; Thyroid function; Treatment efficacy
Subject
Medicine and Pharmacology, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.