Version 1
: Received: 21 December 2023 / Approved: 22 December 2023 / Online: 26 December 2023 (04:16:04 CET)
How to cite:
Al-Agamy, M. H.; Kelany, M. S.; Mahdi, W. A.; Alshehri, S.; Alhuzani, M. R.; Hamed, M. M. Multifaceted Applications of Silver Nanoparticles Synthesized from Marine Fungus Aspergillus flavus MK4: Antimicrobial, Anticancer, and Wound-Healing Properties. Preprints2023, 2023121737. https://doi.org/10.20944/preprints202312.1737.v1
Al-Agamy, M. H.; Kelany, M. S.; Mahdi, W. A.; Alshehri, S.; Alhuzani, M. R.; Hamed, M. M. Multifaceted Applications of Silver Nanoparticles Synthesized from Marine Fungus Aspergillus flavus MK4: Antimicrobial, Anticancer, and Wound-Healing Properties. Preprints 2023, 2023121737. https://doi.org/10.20944/preprints202312.1737.v1
Al-Agamy, M. H.; Kelany, M. S.; Mahdi, W. A.; Alshehri, S.; Alhuzani, M. R.; Hamed, M. M. Multifaceted Applications of Silver Nanoparticles Synthesized from Marine Fungus Aspergillus flavus MK4: Antimicrobial, Anticancer, and Wound-Healing Properties. Preprints2023, 2023121737. https://doi.org/10.20944/preprints202312.1737.v1
APA Style
Al-Agamy, M. H., Kelany, M. S., Mahdi, W. A., Alshehri, S., Alhuzani, M. R., & Hamed, M. M. (2023). Multifaceted Applications of Silver Nanoparticles Synthesized from Marine Fungus<em> Aspergillus flavus</em> MK4: Antimicrobial, Anticancer, and Wound-Healing Properties. Preprints. https://doi.org/10.20944/preprints202312.1737.v1
Chicago/Turabian Style
Al-Agamy, M. H., Mohammad R Alhuzani and Moaz M Hamed. 2023 "Multifaceted Applications of Silver Nanoparticles Synthesized from Marine Fungus<em> Aspergillus flavus</em> MK4: Antimicrobial, Anticancer, and Wound-Healing Properties" Preprints. https://doi.org/10.20944/preprints202312.1737.v1
Abstract
Due to their wide range of uses in modern technology, nanomaterial’s of silver metallic (Ag-NPs) have engaged considerable concern, driving significant research with development efforts. This study focuses on investigating the antimicrobial properties of Ag-NPs, encompassing their production, characterization, and biological aspects. The eco-friendly extracellular biosynthetic method employed in this work utilized extracts from the marine fungus Aspergillus flavus MK4 as reducing agents for nanoparticle synthesis. Analyzing the colloidal Ag-NPs using UV-visible spectroscopy revealed a peak in absorbance at 460 nm, indicating the presence of plasmonic properties. The electrons imaging of internal structure (TEM) elucidated spherical shape of the Ag-NPs by 15 nm size. Testing against bacterial diversities (Gr-ve & Gr+ve) revealed potent antibacterial and antifungal efficacy. Cytotoxicity versus HepG-2 cell line was assessed using the MTT assay, and antioxidant properties were examined through the radical scavenging (DPPH) assay. In wise of their conceivable applications in the fields of antibacterial, anticancer, and wound-healing, the Ag-NPs that were synthesized exhibit promising features. With its powerful ability to synthesize silver nanoparticles (Ag-NP), Aspergillus flavus MK4 Aspergillus flavus MK4 can generate nanoparticles extensively characterized, demonstrating their antibacterial, antioxidant, anticancer, and wound-healing properties.
Public Health and Healthcare, Public Health and Health Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.