Ferrari, I. V. Amentoflavone’s Antimicrobial Potential: Molecular Docking Studies Targeting Mycobacterium tuberculosis, Helicobacter pylori, Haemophilus influenzae, and Pseudomonas aeruginosa. Preprints2024, 2024011550. https://doi.org/10.20944/preprints202401.1550.v1
APA Style
Ferrari, I. V. (2024). <strong></strong>Amentoflavone’s Antimicrobial Potential: Molecular Docking Studies Targeting Mycobacterium tuberculosis, Helicobacter pylori, Haemophilus influenzae, and Pseudomonas aeruginosa. Preprints. https://doi.org/10.20944/preprints202401.1550.v1
Chicago/Turabian Style
Ferrari, I. V. 2024 "<strong></strong>Amentoflavone’s Antimicrobial Potential: Molecular Docking Studies Targeting Mycobacterium tuberculosis, Helicobacter pylori, Haemophilus influenzae, and Pseudomonas aeruginosa" Preprints. https://doi.org/10.20944/preprints202401.1550.v1
Abstract
This study investigates the potential antimicrobial utility of the natural substance Amentoflavone against four dangerous bacterial strains—Mycobacterium tuberculosis, Helicobacter pylori, Haemophilus influenzae, and Pseudomonas aeruginosa. Utilizing molecular docking studies, are assessed the binding interactions between Amentoflavone and key protein targets crucial for the viability of these bacteria. The findings suggest promising binding affinities, particularly in the active sites of Aminoglycoside 2'-N-acetyltransferase, Thioredoxin Reductase, N-acetylneuraminate Lyase, and Glucose-1-phosphate Thymidylyltransferase in the respective bacterial strains. While these in silico results provide initial insights, further in vitro and in vivo experiments are essential to validate the biological relevance and efficacy of Amentoflavone as a potential antimicrobial agent against these bacterial pathogens.
Copyright:
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