Case Report
Version 2
Preserved in Portico This version is not peer-reviewed
Nodular Neurogenic Tumor of the Tip of the Tongue
Version 1
: Received: 1 February 2024 / Approved: 2 February 2024 / Online: 2 February 2024 (08:50:47 CET)
Version 2 : Received: 2 February 2024 / Approved: 5 February 2024 / Online: 5 February 2024 (05:35:51 CET)
Version 2 : Received: 2 February 2024 / Approved: 5 February 2024 / Online: 5 February 2024 (05:35:51 CET)
How to cite: Berge, C.; Hafian, H.; Durlach, A. Nodular Neurogenic Tumor of the Tip of the Tongue. Preprints 2024, 2024020130. https://doi.org/10.20944/preprints202402.0130.v2 Berge, C.; Hafian, H.; Durlach, A. Nodular Neurogenic Tumor of the Tip of the Tongue. Preprints 2024, 2024020130. https://doi.org/10.20944/preprints202402.0130.v2
Abstract
Background: Granular cell tumor is a benign neurogenic tumor of the subcutaneous and submucosal area. The tongue is the most affected site of the oral cavity. The clinical presentation is non-specific and manifests as a submucosal nodule or mass. Because of its non-specific presentation, a definitive diagnosis an only be established after a histopathological examination and an immunohistochemical study to search for a neurogenic origin. Methods: We report the case of a 48-year-old man who was referred for the management of a nodular lesion on the tip of his tongue that had increased in size over the previous three months. Results: A complete surgical excision was performed for the histopathological exam, and an immunohistochemical study confirmed a strong expression of S100 and CD68. A diagnosis of granular cell tumor was confirmed. There was no recurrence et three years follow-up. Conclusion: the GCT is a rare tumor of nervous origin of the oral mucosa, it is non-specific in expression, with a good prognosis after complete excision. the histological and immunohistochemical diagnosis of the lesion is essential for the diagnosis.
Keywords
Benign nerve sheath tumors; Abrikossoff’s tumor; granular cell; oral pathologist; peripheral nerve disorders; tongue; s100 protein
Subject
Medicine and Pharmacology, Dentistry and Oral Surgery
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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