Sass, J.-O.; Henke, P.; Mitrovic, A.; Weinmann, M.; Kluess, D.; Johannsen, J.; Sellin, M.-L.; Lembke, U.; Reimer, D.; Lork, C.; Jonitz-Heincke, A.; Bader, R. Multifunctional Hybrid Material for Endoprosthetic Implants Based on Alumina-Toughened Zirconia Ceramics and Additively Manufactured TiNbTa Alloys. Materials2024, 17, 1838.
Sass, J.-O.; Henke, P.; Mitrovic, A.; Weinmann, M.; Kluess, D.; Johannsen, J.; Sellin, M.-L.; Lembke, U.; Reimer, D.; Lork, C.; Jonitz-Heincke, A.; Bader, R. Multifunctional Hybrid Material for Endoprosthetic Implants Based on Alumina-Toughened Zirconia Ceramics and Additively Manufactured TiNbTa Alloys. Materials 2024, 17, 1838.
Sass, J.-O.; Henke, P.; Mitrovic, A.; Weinmann, M.; Kluess, D.; Johannsen, J.; Sellin, M.-L.; Lembke, U.; Reimer, D.; Lork, C.; Jonitz-Heincke, A.; Bader, R. Multifunctional Hybrid Material for Endoprosthetic Implants Based on Alumina-Toughened Zirconia Ceramics and Additively Manufactured TiNbTa Alloys. Materials2024, 17, 1838.
Sass, J.-O.; Henke, P.; Mitrovic, A.; Weinmann, M.; Kluess, D.; Johannsen, J.; Sellin, M.-L.; Lembke, U.; Reimer, D.; Lork, C.; Jonitz-Heincke, A.; Bader, R. Multifunctional Hybrid Material for Endoprosthetic Implants Based on Alumina-Toughened Zirconia Ceramics and Additively Manufactured TiNbTa Alloys. Materials 2024, 17, 1838.
Abstract
Aseptic implant loosening after total joint replacement is partially influenced by material-specific factors when cobalt-chromium alloys are used, including osteolysis induced by wear- and corrosion products, and stress shielding. Here, we aim to characterize a hybrid material consisting of alumina-toughened zirconia ceramics (ATZ) and additively manufactured Ti-35Nb-6Ta (TiNbTa), joined by a glass solder. The structure of the joint, static and fatigue shear strength, the influence of accelerated aging, and the cytotoxicity using an elution assay with human osteoblasts is characterized. Furthermore, the biomechanical properties of functional demonstrators of a femoral component for total knee replacements are evaluated. TiNbTa-ATZ specimens showed a homogenous joint with statistical distributed micro-pores and a slight accumulation of Al-rich compounds at the glass solder-TiNbTa interface. The static shear strength was 26.4 ± 4.2 MPa (Ti-ATZ reference: 38.2 ± 14.4 MPa, p = 0.117), all specimens survived 107 cycles of shear loading to 10 MPa, and aging did not reduce the strength. TiNbTa-ATZ did not impair the proliferation and metabolic activity of human osteoblasts. Functional demonstrators of TiNbTa-ATZ provided a maximum bearable extension-flexion moment of 40.7 ± 2.2 Nm. Biomechanical and biological properties of TiNbTa-ATZ demonstrate potential application for endoprosthetic implants.
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