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Radical Cyclization-initiated Difunctionalization Reactions of Alkenes and Alkynes
Version 1
: Received: 12 April 2024 / Approved: 12 April 2024 / Online: 15 April 2024 (08:01:52 CEST)
A peer-reviewed article of this Preprint also exists.
Zhi, S.; Ma, X.; Zhang, W. Radical Cyclization-Initiated Difunctionalization Reactions of Alkenes and Alkynes. Molecules 2024, 29, 2559. Zhi, S.; Ma, X.; Zhang, W. Radical Cyclization-Initiated Difunctionalization Reactions of Alkenes and Alkynes. Molecules 2024, 29, 2559.
Abstract
Radical reactions are powerful in the synthesis of diverse molecular scaffolds bearing functional groups. In pervious review articles, we have presented 1,2-difunctionalizations, remote 1,3-, 1,4-, 1,5-, 1,6- and 1,7-difunctionalizations, and addition followed by cyclization reactions. Presents in this paper are radical cyclization followed by the second functionalization reactions. The second functionalization could be realized by atom transfer reactions, radical or transition metal-assisted coupling reactions, and reactions with neutral molecules, cationic and anionic species.
Keywords
radical; difunctionalization; atom transfer; cyclization; coupling; addition
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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