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Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Ultrasound B-mode Visualization of Imperceptible Subwavelength Vibration in Magnetomotive Ultrasound Imaging

Version 1 : Received: 7 May 2024 / Approved: 9 May 2024 / Online: 10 May 2024 (13:09:56 CEST)

A peer-reviewed article of this Preprint also exists.

Shen, W.-H.; Yeh, T.-M.; Liao, M.-Y.; Li, M.-L. Ultrasound B-Mode Visualization of Imperceptible Subwavelength Vibration in Magnetomotive Ultrasound Imaging. Vibration 2024, 7, 764-775. Shen, W.-H.; Yeh, T.-M.; Liao, M.-Y.; Li, M.-L. Ultrasound B-Mode Visualization of Imperceptible Subwavelength Vibration in Magnetomotive Ultrasound Imaging. Vibration 2024, 7, 764-775.

Abstract

Magnetomotive ultrasound (MMUS) is a promising imaging modality for detecting magnetic nanoparticles. In MMUS, an external oscillating magnetic field induces motion of the injected magnetic nanoparticles within tissue, and phase-based tracking algorithms are used to detect the motion. However, the subwavelength scale of theses displacements (often a few micrometers) makes direct visualization on conventional ultrasound B-mode images impossible. In this work, we adapt the Eulerian motion magnification technique to create a novel ultrasound display mode for identifying the nanoparticle locations, eliminating the need for displacement tracking algorithms. Phantom and in-vivo experiments demonstrate that our technique successfully magnifies magnetomotion and the associated shear wave propagation in ultrasound B-mode imaging and pinpoints the nanoparticle vibration source, even in low-concentration scenarios. Additionally, motion magnification magnified the displacement of nanoparticles, having the potential to improve the localization accuracy of displacement tracking algorithms in MMUS.

Keywords

motion magnification; ultrasound imaging; magnetomotive ultrasound; shear wave propagation

Subject

Engineering, Bioengineering

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