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Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Optimization of Magnetic Susceptibility Weighted Imaging for Female Pelvic Scans

Version 1 : Received: 7 June 2024 / Approved: 7 June 2024 / Online: 7 June 2024 (10:24:25 CEST)

How to cite: Liu, W.; Yu, B.; Lv, F.; Liang, K.; Xiao, Z. Optimization of Magnetic Susceptibility Weighted Imaging for Female Pelvic Scans. Preprints 2024, 2024060479. https://doi.org/10.20944/preprints202406.0479.v1 Liu, W.; Yu, B.; Lv, F.; Liang, K.; Xiao, Z. Optimization of Magnetic Susceptibility Weighted Imaging for Female Pelvic Scans. Preprints 2024, 2024060479. https://doi.org/10.20944/preprints202406.0479.v1

Abstract

Background and Objectives: The existing recommendations for female pelvic magnetic susceptibility weighted imaging MRI (FP-SWI) have not been optimized to capture the disease characteristics of the female pelvis. Therefore, it is imperative to explore acquisition parameters before conducting larger-scale studies. To establish optimized flip angle (FA) for acquiring FP-SWI to improve the image quality of female pelvic lesion sites. Materials and Methods: To evaluate signal quality and lesion conspicuity, regions of interest (ROIs) were manually drawn within the lesion on SWI sequences. Signal intensity was measured within the ROIs. Additionally, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated for SWI sequences acquired at three FA: 10°, 15°, and 20°. Finally, a qualitative assessment of anatomical detail visualization, geometric distortion extent, artifacts, and lesion clarity was performed using a four-point scale. The Wilcoxon rank sum test was employed to compare the qualitative evaluation parameters. The intra-class correlation coefficient (ICC) was calculated to determine the consistency of subjective ratings between two observers. Results: FA=10° showed significantly higher SNR than FA=15° and 20° in most anatomical regions (P<0.05), while the CNR was significantly higher than FA=15° and 20° (P<0.05). Compared with FA=15° and 20°, the image quality of FA=10° was significantly higher, with less distortion and ghosting, and better image contrast (P<0.05). Lesions with FA=10° exhibited higher clarity compared to FA=15° and 20° (P<0.05). Conclusions: The image quality of FP-SWI images at FA=10° exceeds that at FA=15° and 20°. We recommend that when conducting SWI examination of the female pelvic cavity, the FA value should be set at 10° to stabilize the SWI sequence and improve image quality.

Keywords

magnetic resonance imaging; magnetic susceptibility weighted imaging; flip angle; pelvic disease.

Subject

Public Health and Healthcare, Other

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