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Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A Case of Autoimmune Acute Disseminated Encephalomyelitis in an Adult Female with Systemic Lupus Erythematosus

Version 1 : Received: 14 June 2024 / Approved: 15 June 2024 / Online: 17 June 2024 (08:34:45 CEST)

A peer-reviewed article of this Preprint also exists.

Sherwani, Y.; Alsaab, A.; Sengodan, M. ADEM as an Initial Presentation of SLE: A Case Report. Reports 2024, 7, 53. Sherwani, Y.; Alsaab, A.; Sengodan, M. ADEM as an Initial Presentation of SLE: A Case Report. Reports 2024, 7, 53.

Abstract

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder of the white matter. Pathophysiology is thought to be immune mediated as in most cases the condition follows an infection or triggering incident. More recent literature has demonstrated that there may be a link between autoimmune conditions and ADEM. Here we present a case of ADEM in a middle-aged woman with systemic lupus erythematosus that recovered well after treatment with corticosteroids and Rituximab.

Keywords

autoimmune diseases; demyelinating; brain; anti dna antibodies; rituximab; IVIG

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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