14 Regular Season Pick Sixes
3 Go-Ahead, 1 Tying, Long of 78 yards
| 2003 | 4 |
| 2007 | 3 |
| 2002 | 3 |
| 2004 | 2 |
| 2006 | 1 |
| Home | 8 |
| Road | 6 |
| Sunday | 13 |
| Thursday | 1 |
| 3rd | 4 |
| 4th | 4 |
| 1st | 3 |
| 2nd | 3 |
| 30 or more yards | 9 |
| 20-29 yards | 3 |
| 10-19 yards | 2 |
Regular Season
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2002 | 2002-09-22 | 3 | 3 | GNB | @ | DET | W 37-31 | 1 | 78 | Marques Anderson | Trail 0-7 | Tied 7-7 |
| 2 | 2002 | 2002-11-10 | 9 | 10 | GNB | DET | W 40-14 | 2 | 14 | Marques Anderson | Lead 16-7 | Lead 23-7 | |
| 3 | 2002 | 2002-11-28 | 12 | 13 | NWE | @ | DET | W 20-12 | 1 | 27 | Tedy Bruschi | Lead 3-0 | Lead 10-0 |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 4 | 2003 | 2003-09-14 | 2 | 2 | GNB | DET | W 31-6 | 4 | 56 | Al Harris | Lead 24-6 | Lead 31-6 | |
| 5 | 2003 | 2003-10-19 | 6 | 7 | DAL | @ | DET | W 38-7 | 2 | 27 | Mario Edwards | Lead 21-7 | Lead 28-7 |
| 6 | 2003 | 2003-11-23 | 11 | 12 | MIN | DET | W 24-14 | 4 | 32 | Corey Chavous | Lead 10-7 | Lead 17-7 | |
| 7 | 2003 | 2003-11-23 | 11 | 12 | MIN | DET | W 24-14 | 4 | 42 | Brian Williams | Lead 17-7 | Lead 24-7 | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 8 | 2004 | 2004-10-17 | 6 | 6 | GNB | @ | DET | W 38-10 | 3 | 36 | Darren Sharper | Lead 17-10 | Lead 24-10 |
| 9 | 2004 | 2004-12-26 | 15 | 16 | CHI | @ | DET | L 13-19 | 3 | 38 | Lance Briggs | Trail 0-16 | Trail 6-16 |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 10 | 2005 | 2005-09-18 | 2 | 2 | CHI | DET | W 38-6 | 2 | 41 | Mike Brown | Lead 24-6 | Lead 31-6 | |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 11 | 2006 | 2006-10-22 | 6 | 7 | GNB | @ | MIA | W 34-24 | 3 | 23 | Charles Woodson* | Trail 6-10 | Lead 13-10* |
| Rk | Year | Date | G# | Week | Tm | Opp | Result | Quarter | Dist | Scorer | Score Before | Score After | |
| 12 | 2007 | 2007-09-09 | 1 | 1 | MIN | ATL | W 24-3 | 1 | 54 | Kevin Williams | Tied 0-0 | Lead 7-0* | |
| 13 | 2007 | 2007-09-09 | 1 | 1 | MIN | ATL | W 24-3 | 4 | 14 | Antoine Winfield | Lead 17-3 | Lead 24-3 | |
| 14 | 2007 | 2007-10-07 | 4 | 5 | TEN | ATL | W 20-13 | 3 | 76 | Vincent Fuller | Tied 13-13 | Lead 20-13* |
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