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aggrecan (Q21121862)

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mammalian protein found in Homo sapiens

aggrecan core protein
ACAN
Chondroitin sulfate proteoglycan 1
large aggregating proteoglycan
chondroitin sulfate proteoglycan core protein 1
CSPCP
cartilage-specific proteoglycan core protein
aggrecans

Language	Label	Description	Also known as
English	aggrecan	mammalian protein found in Homo sapiens	aggrecan core protein ACAN Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan chondroitin sulfate proteoglycan core protein 1 CSPCP cartilage-specific proteoglycan core protein aggrecans

Statements

1 reference

13 November 2019

UniProt protein ID

C-type lectin-like/link domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

C-type lectin fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Sushi/SCR/CCP superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Link domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin V-set domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aggrecan/versican, C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin/major histocompatibility complex, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

extracellular matrix structural constituent

determination method

1 reference

8 April 2019

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

protein binding

determination method

1 reference

8 April 2019

Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

carbohydrate binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

hyaluronic acid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

extracellular matrix structural constituent conferring compression resistance

determination method

extracellular matrix structural constituent conferring compression resistance

determination method

4 references

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

1 January 2018

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

1 January 2018

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

1 January 2018

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

lysosomal lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

basement membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

perisynaptic extracellular matrix

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

glutamatergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

GABA-ergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

biological process

skeletal system development

determination method

extracellular matrix disassembly

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P16112&geneProductId=UniProtKB:P16112

determination method

extracellular matrix organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

determination method

1 reference

8 April 2019

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

central nervous system development

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

keratan sulfate catabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

keratan sulfate biosynthetic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

cartilage condensation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

chondrocyte development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

heart development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

proteoglycan biosynthetic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

collagen fibril organization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16112

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Immunoglobulin/major histocompatibility complex, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

sushi/SCR/CCP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

C-type lectin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

immunoglobulin V-set domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

immunoglobulin subtype

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Aggrecan/versican, C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16112

Identifiers

MeSH descriptor ID

subject named as

Aggrecans

0 references

D09.698.735.200.500

0 references

D12.776.395.650.750.687.100

0 references

D12.776.503.280.437.100

0 references

D12.776.860.300.140

0 references

D09.400.430.930.750.687.100

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000453499

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453499

ENSP00000453003

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453003

ENSP00000452682

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452682

ENSP00000341615

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000341615

ENSP00000387356

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000387356

ENSP00000453342

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453342

ENSP00000453581

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453581

ENSP00000484456

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484456

Google Knowledge Graph ID

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(10 entries)

cywiki ACAN
dewiki Aggrecan
enwiki Aggrecan
eswiki Agrecano
fawiki اگریکان
frwiki Agrécane
huwiki Aggrekán
itwiki Aggrecano
ruwiki Аггрекан
ukwiki ACAN

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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