Measles Immune Suppression: Lessons from the Macaque Model
Figure 3
Histology and immunohistochemistry of lymphoid tissues obtained from macaques euthanized between 5 and 15 d.p.i.
Serial sections were stained for histological changes (H&E), MV infection (EGFP), B-lymphocytes (CD20), T-lymphocytes (CD3) or proliferating cells (Ki67). Multiple lymphoid tissues from multiple animals collected at each time-point were analyzed, panels shown are representative for the tissues that have been examined. The color intensity of the blue bars below the photomicrographs indicates the relative levels of viremia, lymphocyte depletion or proliferation. The green and red bars at the bottom indicate the appearance and disappearance of viremia and rash and correspond to the bars in Figure 5B.