Explore the latest in critical care medicine, including management of respiratory failure, sepsis, HAI prevention, end-of-life care, and more.
This cohort study assesses whether use of medications to control blood pressure in patients who have undergone endovascular thrombectomy for acute ischemic stroke is associated with functional outcomes at 3 months.
In this narrative medicine essay, a pediatric critical care physician mulls a discussion about a patient’s status with a male colleague in front of her all-female medical team, a discussion that led her to question herself until she concludes that she can’t be all things to all people at all times.
This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality.
This cross-sectional study investigates perioperative oxygen saturation differences in Black and White infants with single ventricles undergoing stage 1 palliation.
This cohort study describes and compares clinical and radiographic features, treatment responses, and outcomes of neuroinvasive West Nile virus infection in individuals with and without immunosuppression.
This cohort study examines whether the use of an artificial intelligence–enabled deterioration model is associated with a decrease in the risk of escalations in care in hospitalized patients.
This randomized clinical trial assesses the effect of targeting a lower vs higher oxygenation level on 90-day survival without need for life support among intensive care unit patients with COVID-19 and severe hypoxemia.
This cohort study examines whether peripheral oxygenation-saturation targets on mortality would differ by individual patient characteristics among 2 temporally and geographically distinct randomized trials of lower vs higher Spo2 targets in critically ill patients receiving mechanical ventilation
This JAMA Guide to Statistics and Methods article explains effect score analyses, an approach for evaluating the heterogeneity of treatment effects, and examines its use in a study of oxygen-saturation targets in critically ill patients.
This cohort study assesses whether severe sepsis during treatment for childhood acute leukemia is associated with increased incidence of long-term organ dysfunction among adult survivors using observational data from the St Jude Lifetime Cohort Study.
This cohort study examines the natural history and response to treatment of sodium glucose cotransporter 2 (SGLT2) inhibitor–associated ketoacidosis compared with that of type 1 diabetes–associated ketoacidosis.
This cohort study assesses changes in intensive care unit (ICU) admission rate, hospital length of stay, and use of noninvasive and invasive ventilation after the adoption of weight-based high-flow nasal cannula protocol in hospitalized patients aged 0 to 24 months.
This cluster randomized clinical trial assesses the extent to which video laryngoscopy compared with direct laryngoscopy might facilitate intubation in patients undergoing surgical procedures during routine clinical practice.
This cohort study assesses the association between number of recent pediatric intensive care unit (PICU) critical illness episodes and survival among children with severe neurologic impairment.
This cross-sectional study examines the prevalence of anxiety, depression, posttraumatic stress disorder, and physical somatic symptoms in adult and pediatric patients with induced laryngeal obstruction.
This cohort study evaluates prevalence and factors associated with bacteremia from a presumed urinary source in inpatients with asymptomatic bacteriuria with or without altered mental status.
This cohort study assesses in-hospital mortality among adults at US rural and urban hospitals during vs before the COVID-19 pandemic for non–COVID-19 time-sensitive conditions.
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