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Page 1
Actin cytoskeleton remodeling primes RIG-I-like receptor activation.
Acharya D, Reis R, Volcic M, Liu G, Wang MK, Chia BS, Nchioua R, Groß R, Münch J, Kirchhoff F, Sparrer KMJ, Gack MU. Acharya D, et al. Cell. 2022 Sep 15;185(19):3588-3602.e21. doi: 10.1016/j.cell.2022.08.011. Cell. 2022. PMID: 36113429 Free PMC article.
TRIM23 mediates virus-induced autophagy via activation of TBK1.
Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU. Sparrer KMJ, et al. Nat Microbiol. 2017 Nov;2(11):1543-1557. doi: 10.1038/s41564-017-0017-2. Epub 2017 Sep 4. Nat Microbiol. 2017. PMID: 28871090 Free PMC article.
The antiviral activities of TRIM proteins.
Koepke L, Gack MU, Sparrer KM. Koepke L, et al. Curr Opin Microbiol. 2021 Feb;59:50-57. doi: 10.1016/j.mib.2020.07.005. Epub 2020 Aug 20. Curr Opin Microbiol. 2021. PMID: 32829025 Free PMC article. Review.
GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141.
Naesens L, Muppala S, Acharya D, Nemegeer J, Bogaert D, Lee JH, Staes K, Debacker V, De Bleser P, De Bruyne M, De Baere E, van Gent M, Liu G, Lambrecht BN, Staal J, Kerre T, Beyaert R, Maelfait J, Tavernier SJ, Gack MU, Haerynck F. Naesens L, et al. Sci Immunol. 2022 Nov 25;7(77):eabq4531. doi: 10.1126/sciimmunol.abq4531. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399538 Free PMC article.
52 results