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Coronavirus and birth in Italy: results of a national population-based cohort study

Ann Ist Super Sanita. 2020 Jul-Sep;56(3):378-389. doi: 10.4415/ANN_20_03_17.

Abstract

Introduction: The study was implemented to provide guidance to decision-makers and clinicians by describing hospital care offered to women who gave birth with confirmed SARS-CoV-2 infection.

Materials and methods: National population-based prospective cohort study involving all women with confirmed SARS-CoV-2 infection who gave birth between February 25 and April 22, 2020 in any Italian hospital.

Results: The incidence rate of confirmed SARS-CoV-2 infection in women who gave birth was 2.1 per 1000 maternities at a national level and 6.9/1000 in the Lombardy Region. Overall one third of the women developed a pneumonia and 49.7% assumed at least one drug against SARS-CoV-2 infection. Caesarean rate was 32.9%, no mothers nor newborns died. Six percent of the infants tested positive for SARS-CoV-2 at birth.

Conclusions: Clinical features and outcomes of COVID-19 in women who gave birth are similar to those described for the general population, most women developing mild to moderate illness.

Publication types

  • Observational Study

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Betacoronavirus*
  • COVID-19
  • COVID-19 Drug Treatment
  • Cesarean Section / statistics & numerical data
  • Coronavirus Infections / congenital
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / therapy
  • Coronavirus Infections / transmission
  • Emigrants and Immigrants / statistics & numerical data
  • Female
  • Fetal Organ Maturity / drug effects
  • Humans
  • Incidence
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical / statistics & numerical data
  • Italy / epidemiology
  • Lung / embryology
  • Pandemics*
  • Pneumonia, Viral / congenital
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / therapy
  • Pneumonia, Viral / transmission
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology
  • Pregnancy Outcome
  • Premature Birth / epidemiology
  • Procedures and Techniques Utilization
  • Prospective Studies
  • SARS-CoV-2
  • Stillbirth / epidemiology

Substances

  • Adrenal Cortex Hormones