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How Nine Covid-19 Vaccines Work

This tracker followed the early development of selected Covid vaccines through May 2021. It is no longer being updated.

Researchers are testing 90 coronavirus vaccines in clinical trials on humans. Here are explanations about how nine of the leading vaccines work.

Messenger RNA Vaccines

Comirnaty

How the Pfizer-BioNTech Vaccine Works

Cómo funciona la vacuna de Pfizer-BioNTech

The vaccine, known as Comirnaty, has been approved in several countries and authorized for emergency use in many others, including the United States and the European Union.

mRNA-1273

How Moderna’s Vaccine Works

Cómo funciona la vacuna de Moderna

The vaccine, known as mRNA-1273, has been approved in Switzerland and authorized for emergency use in many countries, including the United States and the European Union.

Adenovirus-Based Vaccines

AZD1222

How the Oxford-AstraZeneca Vaccine Works

Cómo funciona la vacuna de Oxford-AstraZeneca

The vaccine, known as AZD1222 or Covishield, is approved in Brazil and authorized for emergency use in dozens of countries.

Ad26.COV2.S

How the Johnson & Johnson Vaccine Works

Cómo funciona la vacuna de Johnson & Johnson

The vaccine, called Ad26.COV2.S, is authorized for emergency use in the United States, the European Union, Canada and other countries.

Sputnik V

(Ad26)

Sputnik V

(Ad5)

How the Gamaleya Vaccine Works

Cómo funciona la vacuna Gamaleya

The vaccine, known as Sputnik V or Gam-Covid-Vac, is a combination of two different Adenoviruses, Ad26 and Ad5. The vaccine is in use in Russia and is authorized for emergency use in dozens of other countries.

Protein-Based Vaccines

NVX-CoV2373

nanoparticle

How the Novavax Vaccine Works

The vaccine, known as NVX-CoV2373, is in Phase 3 clinical trials. The vaccine has not been authorized by any country.

Inactivated Coronavirus Vaccines

BBIBP-CorV

How the Sinopharm Vaccine Works

Cómo funciona la vacuna de Sinopharm

The vaccine, known as BBIBP-CorV, is approved in China, Bahrain and the United Arab Emirates, and has been authorized for emergency use in several other countries.

CoronaVac

How the Sinovac Vaccine Works

Cómo funciona la vacuna de Sinovac

阅读简体中文版 · 閱讀繁體中文版

The vaccine, known as CoronaVac, is approved in China and authorized for emergency use in several other countries.

Covaxin

How Bharat Biotech’s Vaccine Works

The vaccine, known as Covaxin, is authorized for emergency use in India and several other countries.

See the Coronavirus Vaccine Tracker for more information, and for the status of other vaccines in development.

Tracking the Coronavirus