Childhood Tumors around the Knee Revisited: Predilection Sites for Most Entities Confirmed
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Bone Tumors
3.2. Soft-Tissue Tumors
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Male | Female | 0–4 Years | 5–9 Years | 10–14 Years | 15–18 Years | All | ||
---|---|---|---|---|---|---|---|---|
all | 138 | 86 | 2 | 13 | 92 | 117 | 224 | |
62% | 38% | 1% | 6% | 41% | 52% | |||
bone | all | 124 | 60 | 1 | 11 | 77 | 95 | 184 |
tumors | 67% | 33% | 1% | 6% | 42% | 51% | ||
benign | 101 | 42 | 0 | 7 | 60 | 76 | 143 | |
71% | 29% | 0% | 5% | 42% | 53% | |||
malignant | 23 | 18 | 1 | 4 | 17 | 19 | 41 | |
56% | 44% | 2% | 10% | 42% | 46% | |||
soft tissue | all | 14 | 26 | 1 | 2 | 15 | 22 | 40 |
tumors | 35% | 65% | 3% | 5% | 38% | 54% | ||
benign | 10 | 20 | 0 | 1 | 12 | 17 | 30 | |
33% | 67% | 0% | 3% | 40% | 57% | |||
malignant | 4 | 6 | 1 | 1 | 3 | 5 | 10 | |
40% | 60% | 10% | 10% | 30% | 50% |
Benign Bone Tumors | Malignant Bone Tumors | ||||
---|---|---|---|---|---|
Osteochondroma | 88 | 62% | Osteosarcoma | 33 | 80% |
Bone cyst | 20 | 14% | - osteoblastic | 20 | 49% |
- aneurysmatic | 12 | 8% | - teleangiektatic | 5 | 12% |
- unicameral | 8 | 6% | - mixed | 3 | 7% |
Non-ossifying fibroma | 19 | 13% | - chondroblastic | 2 | 5% |
Chondroblastoma | 8 | 6% | - high-grade | 2 | 5% |
Chondroma | 3 | 2% | - parosteal | 1 | 2% |
Enchondroma | 2 | 1% | Ewing‘s sarcoma | 8 | 20% |
Giant-cell tumors | 2 | 1% | |||
Chondromyxoid fibroma | 1 | 1% | |||
all | 143 | all | 41 |
Epiphyses | Metaphyses | Diaphyses | ||||
---|---|---|---|---|---|---|
Patients | Percentage | Patients | Percentage | Patients | Percentage | |
Osteochondroma | 0 | 0% | 85 | 100% | 0 | 0% |
Bone cyst | 0 | 0% | 16 | 89% | 2 | 11% |
- aneurysmatic | 0 | 0% | 9 | 90% | 1 | 10% |
- unicameral | 0 | 0% | 7 | 88% | 1 | 12% |
Non-ossifying fibroma | 0 | 0% | 16 | 84% | 3 | 16% |
Chondroblastoma | 0 | 0% | 7 | 88% | 1 | 12% |
Chondroma | 0 | 0% | 3 | 100% | 0 | 0% |
Enchondroma | 1 | 50% | 1 | 50% | 0 | 0% |
Giant-cell tumors | 1 | 50% | 1 | 50% | 0 | 0% |
Chondromyxoid fibroma | 0 | 0% | 1 | 100% | 0 | 0% |
Osteosarcoma | 3 | 9% | 23 | 70% | 7 | 21% |
Ewing‘s sarcoma | 0 | 0% | 6 | 75% | 2 | 25% |
all | 5 | 3% | 159 | 89% | 15 | 8% |
Benign Soft Tissue Tumors | Malignant Soft Tissue Tumors | |||
---|---|---|---|---|
Tenosynovial giant-cell tumor | 12 | 40% | Alveolar soft part sarcoma | 2 |
- nodular | 7 | 23% | Synovial sarcoma | 2 |
- diffuse | 5 | 17% | Fibrosarcoma | 2 |
Hemangioma | 11 | 37% | Undifferentiated sarcoma | 2 |
Chondromatosis | 2 | 7% | Rhabdomyosarcoma | 1 |
Lipoma | 2 | 7% | Myxoid liposarcoma | 1 |
Fibroma | 1 | 3% | ||
Lipoma aborescens | 1 | 3% | ||
Ganglion cyst of nerve sheathing | 1 | 3% | ||
all | 30 | all | 10 |
Epifascial | Subfascial | Intramuscular | Intra-Articular | |||||
---|---|---|---|---|---|---|---|---|
Patients | Percentage | Patients | Percentage | Patients | Percentage | Patients | Percentage | |
Tenosynovial giant-cell tumor | 0 | 0% | 0 | 0% | 0 | 0% | 12 | 100% |
- nodular | 0 | 0% | 0 | 0% | 0 | 0% | 7 | 100% |
- diffuse | 0 | 0% | 0 | 0% | 0 | 0% | 5 | 100% |
Hemangioma | 1 | 9% | 3 | 27% | 6 | 55% | 1 | 9% |
Chondromatosis | 0 | 0% | 0 | 0% | 0 | 0% | 2 | 100% |
Lipoma | 0 | 0% | 1 | 100% | 0 | 0% | 0 | 0% |
Fibroma | 0 | 0% | 1 | 100% | 0 | 0% | 0 | 0% |
Lipoma aborescens | 0 | 0% | 0 | 0% | 0 | 0% | 1 | 100% |
Ganglion cyst of nerve sheathing | 0 | 0% | 1 | 100% | 0 | 0% | 0 | 0% |
Lymphangioma | 0 | 0% | 0 | 0% | 1 | 100% | 0 | 0% |
all | 1 | 3% | 6 | 20% | 7 | 23% | 16 | 54% |
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Breden, S.; Beischl, S.; Hinterwimmer, F.; Consalvo, S.; Lenze, U.; von Eisenhart-Rothe, R.; Pohlig, F.; Knebel, C. Childhood Tumors around the Knee Revisited: Predilection Sites for Most Entities Confirmed. J. Clin. Med. 2024, 13, 4405. https://doi.org/10.3390/jcm13154405
Breden S, Beischl S, Hinterwimmer F, Consalvo S, Lenze U, von Eisenhart-Rothe R, Pohlig F, Knebel C. Childhood Tumors around the Knee Revisited: Predilection Sites for Most Entities Confirmed. Journal of Clinical Medicine. 2024; 13(15):4405. https://doi.org/10.3390/jcm13154405
Chicago/Turabian StyleBreden, Sebastian, Simone Beischl, Florian Hinterwimmer, Sarah Consalvo, Ulrich Lenze, Rüdiger von Eisenhart-Rothe, Florian Pohlig, and Carolin Knebel. 2024. "Childhood Tumors around the Knee Revisited: Predilection Sites for Most Entities Confirmed" Journal of Clinical Medicine 13, no. 15: 4405. https://doi.org/10.3390/jcm13154405