3.2. Changes in TTE Imaging before and after Kidney Transplantation
Left ventricular interventricular septum measurements of the heart after kidney transplantation did not show a significant (
p > 0.05) change compared those to before kidney transplantation. The proportion of patients with left ventricular diastolic dysfunction increased significantly (
p < 0.05) after kidney transplantation compared to that before kidney transplantation (
Table 2) (
Figure 1). The posterior left ventricle, right atrium (RA), left atrium (LA), pulmonary artery pressure (PAB max), and ejection fraction (EF) values after renal transplantation did not change significantly (
p > 0.05) compared to those before renal transplantation. The right ventricle (RV) value increased significantly (
p < 0.05) after renal transplantation compared to that before renal transplantation. The rate of LVH, mitral insufficiency, aortic insufficiency, and pericardial effusion did not change significantly (
p > 0.05) after kidney transplantation compared to before kidney transplantation. The rate of HT, antihypertensive drug use, and DM increased significantly (
p < 0.05). The rate of coronary artery disease (CAD) and acute coronary syndrome (ACS) after kidney transplantation did not change significantly (
p > 0.05) compared to before kidney transplantation (
Table 2).
The age and gender distribution of the patients did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups after kidney transplantation. The height, weight, and BMI values did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups (
Table 3). Dialysis type and duration of dialysis did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups. Donor proximity did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups. The deceased donor transplantation rate was significantly (
p < 0.05) higher in the GFR < 45 group than in the GFR > 45 group (
Table 3).
There was no significant (
p > 0.05) difference in the rate of left ventricular diastolic dysfunction between the GFR < 45 and GFR > 45 groups before and after kidney transplantation (
Figure 1). In the GFR < 45 group, the rate of left ventricular diastolic dysfunction increased significantly (
p < 0.05) after kidney transplantation compared to that before kidney transplantation. In the group with GFR > 45, the rate of diastolic dysfunction increased significantly (
p < 0.05) after kidney transplantation compared to that before kidney transplantation (
Table 4). The RV value before and after kidney transplantation did not differ significantly (
p > 0.05) between the groups with GFR < 45 and GFR > 45. In the GFR < 45 group, the RV value after kidney transplantation did not change significantly (
p > 0.05) compared to that before kidney transplantation. In the group with GFR > 45, the RV value increased significantly (
p < 0.05) after kidney transplantation compared to that before kidney transplantation. There was no significant (
p > 0.05) difference between the GFR < 45 and GFR > 45 groups in terms of RV increase before/after kidney transplantation (
Table 5).
The PAB max value did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups before kidney transplantation compared to after kidney transplantation. The PAB max value after kidney transplantation in the GFR < 45 group was significantly (
p < 0.05) higher than that in the GFR > 45 group (
Figure 2). In the group with GFR < 45, the PAB max value after kidney transplantation increased significantly (
p < 0.05) compared to that before kidney transplantation. In the group with GFR > 45, the PAB max value after TX decreased significantly (
p < 0.05) compared to that before kidney transplantation. In the group with GFR < 45, the change in PAB max before/after kidney transplantation was significantly (
p < 0.05) higher than in the group with GFR > 45. An increase was observed in the group with GFR < 45, and a decrease was observed in the group with GFR > 45 (
Table 5). In the group with GFR < 45, the EF value before and after kidney transplantation was significantly (
p < 0.05) lower than in the group with GFR > 45. In the GFR < 45 group, the EF value after kidney transplantation did not change significantly (
p > 0.05) compared to that before kidney transplantation. In the GFR > 45 group, the EF value after kidney transplantation did not change significantly (
p > 0.05) compared to that before kidney transplantation. There was no significant (
p > 0.05) difference between the groups with GFR < 45 and GFR > 45 in terms of EF change before/after kidney transplantation (
Table 5).
There was no significant (
p > 0.05) difference in LVH rate between the GFR < 45 and GFR > 45 groups before and after kidney transplantation. In the group with GFR < 45, the LVH rate after kidney transplantation did not change significantly (
p > 0.05) compared to that before kidney transplantation. In the group with GFR > 45, the LVH rate after kidney transplantation did not show a significant (
p > 0.05) change compared to that before kidney transplantation (
Table 6).
The pericardial effusion rate before kidney transplantation did not differ significantly (
p > 0.05) between the GFR < 45 and GFR > 45 groups. The rate of pericardial effusion after TX was significantly (
p < 0.05) higher in the GFR < 45 group than in the GFR > 45 group. In the group with GFR < 45, the rate of pericardial effusion after kidney transplantation did not change significantly (
p > 0.05) compared to that before TX. In the group with GFR > 45, the rate of pericardial effusion after TX decreased significantly (
p < 0.05) compared to that before TX (
Table 7).
There was no significant (p > 0.05) difference between the groups with GFR < 45 and GFR > 45 before and after kidney transplantation. In the group with GFR < 45, the HT rate after kidney transplantation increased significantly (p < 0.05) compared to that before kidney transplantation. In the group with GFR > 45, the rate of HT after kidney transplantation increased significantly (p < 0.05) compared to that before kidney transplantation. The rate of antihypertensive drug use before and after kidney transplantation did not differ significantly (p > 0.05) between the groups with GFR < 45 and GFR > 45. In the group with GFR < 45, the rate of antihypertensive drug use after kidney transplantation increased significantly (p < 0.05) compared to that before kidney transplantation. In the group with GFR > 45, the rate of antihypertensive drug use after kidney transplantation increased significantly (p < 0.05) compared to that before kidney transplantation. The rate of DM before and after kidney transplantation did not differ significantly (p > 0.05) between the groups with GFR < 45 and GFR > 45. In the group with GFR < 45, the DM rate after kidney transplantation did not change significantly (p > 0.05) compared to that before Kidney transplantation. In the group with GFR > 45, the DM rate after kidney transplantation increased significantly (p < 0.05) compared to that before kidney transplantation. The EX rate was significantly (p < 0.05) higher in the group with GFR < 45 than in the group with GFR > 45.
The posterior measurement was larger in non-pre-emptive KTx patients before kidney transplantation (1.08 vs. 0.98,
p < 0.001) (
Table 8). There was a difference between posterior measurement before and after kidney transplantation in pre-emptive patients (1.03 vs. 0.98,
p = 0.049). The change in RA measurement before and after kidney transplantation was greater in pre-emptive patients (−0.07 vs. −0.008,
p = 0.045). There was a difference between pre- and post-kidney transplantation measurements in pre-emptive patients (3.33 vs. 3.2,
p = 0.026). There was a difference in the LA measurement between pre-emptive and non-pre-emptive KTx patients (3.68 vs. 3.47,
p = 0.041). Pericardial effusion was more common in pre-emptive patients before kidney transplantation (11.4% vs. 1.8%,
p = 0.033). There was a significant decrease in the rate of pericardial effusion in patients receiving non-pre-emptive KTx before and after kidney transplantation (11.4% vs. 2.3%,
p = 0.039). LVH was more common in pre-emptive patients before kidney transplantation (66.7% vs. 43.2%,
p = 0.006) (
Table 9).
There was a difference between post-kidney transplant RV and pre-kidney transplant RV in pre-emptive patients (3.25 vs. 2.98,
p < 0.001). Non-pre-emptive KTx recipients had a higher proportion of patients with diastolic dysfunction before kidney transplantation compared to pre-emptive patients (39.8% vs. 19.3%,
p = 0.010). The rate of diastolic dysfunction in pre-emptive patients was higher after kidney transplantation than before kidney transplantation (45.6% vs. 19.3%,
p = 0.001). In patients receiving non-pre-emptive KTx, the rate of diastolic dysfunction was higher after kidney transplantation than before kidney transplantation (56.8% vs. 39.8%,
p = 0.014) (
Table 10).