Molecular Research on Biofilm Formation
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 288
Special Issue Editor
Interests: protein physics; protein folding; protein misfolding; intrinsically disordered proteins; protein function; protein interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biofilms are immobile microbial communities that represent 3D agglomerations of microorganisms, in which bacteria are adhered to each other and to a surface by means of a self-produced matrix of bacterial secreted extracellular polymeric substances, such as exopolysaccharides (EPS), extracellular DNA (e-DNA), proteins and amyloidogenic proteins. Such biofilms represent highly pliable systems that allow their inhabitants to adapt to environmental conditions and tolerate antibiotics, host defense systems, and other external stresses, such as desiccation, nutrient scarcity, mechanical and shear forces, osmolarity, and pH. Biofilms are formed via a set of well-regulated multi-step events, and cell-to-cell communication, signaling, and coordination within the biofilm are conducted via quorum sensing, where the regulation of the expression of specific genes is driven by the accumulation of signaling molecules in the extracellular environment. Biofilms are related to the pathogenesis of biofilm diseases in the auditory, cardiovascular, digestive, integumentary, reproductive, respiratory, and urinary systems. Furthermore, bacterial biofilms play crucial roles in antimicrobial resistance. Therefore, understanding the peculiarities of biofilm biogenesis is crucial for the development of effective treatment strategies for such infections.
Prof. Dr. Vladimir N. Uversky
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biofilm
- extra-cellular matrix
- extracellular polymeric substances
- extracellular DNA
- exopolysaccharides
- quorum sensing
- wound infections
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
