Application of Biosensors in Cell and Tissue Analysis
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 476
Special Issue Editors
Interests: biosensors; cell-based assays; Antibodies
Interests: tissue-based assays; drug development; in vitro and in vivo skills such as mammalian cell culture; qPCR; western blot; immunohistochemistry; FACS; in vivo experiments; microbiology techniques and others
Interests: biomimetic systems; complex mixture modelling and spectroscopic studies of biological; synthetic and hybrid systems; biosensors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell and tissue based assay targeting drug-receptors interactions has proven to significantly increase the success rates in clinical trials. The main reason being the more in vivo like conditions that elucidates the strengths and weaknesses of a drug.
This Special Issue aims at state of the art biosensors for cells and tissues within drug development. The scope is to gathering assays that mimics in vivo conditions as much as possible, hence features such as label-free, kinetics, flow, serological, temperature etc are important. For example, the diffent pH levels in the blood stream and inside cells affect interaction properties. On and off-target interactions are crucial for PK and PD studies, and consequently for efficacy and side effects. We encourage publications combining cell or tissue based biosensor with traditional methods, hence elucidating the added value of this new biosenors for drug development.
Dr. Teodor Aastrup
Dr. Ahmed Ibrahim
Prof. Dr. Ian A. Nicholls
Guest Editors
Manuscript Submission Information
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Keywords
- cell-based
- tissue-based
- biosensors
- drug development
- efficacy
- off-target
- pharmocokinetics
- pharmacodynamics
- kinetics
- label-free
- in vivo
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