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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Progress in Antimicrobial Peptides

edited by

Carla Renata Arciola

submission deadline 15 Jul 2024 | 8 articles | Viewed by 12724

Keywords: anti-microbial peptides (AMPs); antibiotic-resistance; anti-infective materials; implant infections; bacterial biofilms; drug-delivery systems; nanotechnologies; nanocoatings; mesenchymal stem cells; cancer; chronic inflammation

(This special issue belongs to the Section Molecular Microbiology)

G Protein-Coupled Receptors: Signaling, Regulation and Therapeutic Opportunities

edited by J. Adolfo García-Sáinz

submission deadline 15 Jul 2024 | 6 articles | Viewed by 8077

Keywords: GPCR; cell signaling; small molecule drugs; biased signaling; endosomal signaling; post-translational modification; GPCR internalization; phosphorylation barcode

(This special issue belongs to the Section Molecular Pharmacology)

Mitochondrial Bioenergetics in Different Pathophysiological Conditions 4.0

edited by

Anna Atlante

and

Daniela Valenti

submission deadline 15 Jul 2024 | 6 articles | Viewed by 7749

Keywords: mitochondrial ATP generation; oxidative phosphorylation machinery; mitochondrial quality control; mitochondrial dynamic network; mitogenesis/mitophagy; mitochondrial signaling; inter-organelle crosstalk; mitochondrial dysfunction; mitochondria-targeting therapeutic strategies

(This special issue belongs to the Section Biochemistry)

New Sights into Bioinformatics of Gene Regulations and Structure

edited by

Yuriy L. Orlov

Anastasia A. Anashkina

and

Nikolay A. Kolchanov

submission deadline 15 Jul 2024 | 6 articles | Viewed by 7587

Keywords: bioinformatics; systems biology; human genomics; genomics of model organisms; gene expression regulation; transcriptomics; fundamental biomedicine; gene networks; Machine Learning in bioinformatics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Effects of Functional Food Components in Health and Disease

edited by

Shigeyuki Kon

submission deadline 15 Jul 2024 | 4 articles | Viewed by 6322

Keywords: functional food components; life expectancy; autoimmune diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Effect of Ionizing Radiation on Human Cells

edited by

Judith Reindl

and

Omid Azimzadeh

submission deadline 15 Jul 2024 | 4 articles | Viewed by 5713

Keywords: DNA repair; ionizing radiation; radiation induced cellular and molecular response; molecular mechanisms of long-term effects of radiation; radiobiology; cancer treatment

(This special issue belongs to the Section Molecular Biology)

Stem Cell Research: Discovering the Mechanistic Understanding for Therapeutic Application

edited by

Rachel A. Oldershaw

submission deadline 15 Jul 2024 | 2 articles | Viewed by 5499

Keywords: pluripotent stem cells; adult stem cells; bioengineering; regenerative medicine; cell therapy

(This special issue belongs to the Section Molecular Biology)

Molecular and Cellular Mechanisms Underlying Taste, Smell and Beyond, 2nd Edition

edited by

Peihua Jiang

submission deadline 15 Jul 2024 | 3 articles | Viewed by 5117

Keywords: taste receptor; taste preferences; feeding behavior; carbohydrate metabolism; adult stem cells

(This special issue belongs to the Section Biochemistry)

Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment

edited by

Morris Karmazyn

submission deadline 15 Jul 2024 | 4 articles | Viewed by 5070

Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Epilepsy and Seizures

edited by Sara Matricardi

submission deadline 15 Jul 2024 | 3 articles | Viewed by 4727

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Pathogenesis and Therapy of Muscular Dystrophies

edited by Valentina Saccone

submission deadline 15 Jul 2024 | 3 articles | Viewed by 4684

Keywords: muscular dystrophy; myogenesis; muscle regeneration; satellite cells; fibrosis; inflammation; omics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Early-Stage Drug Discovery: Advances and Challenges 2.0

edited by

Wolfgang Sippl

submission deadline 15 Jul 2024 | 2 articles | Viewed by 4442

Keywords: medicinal chemistry; drug discovery; computer-assisted drug design; drug targets; machine learning; epigenetic targets; in vitro assays; biophysical methods; target engagement studies; multi-targeting compounds; PROTAC

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Genetics in Neurodegenerative Disorders: 2nd Edition

edited by

Orietta Pansarasa

and

Matteo Bordoni

submission deadline 15 Jul 2024 | 1 articles | Viewed by 3561

(This special issue belongs to the Section Molecular Genetics and Genomics)

Toxicity of Nanoparticles

edited by Lucyna Kapka-Skrzypczak

submission deadline 15 Jul 2024 | 3 articles | Viewed by 3119

Keywords: nanoparticles; nanotoxicity; exposure to nanoparticles; health effects; biological effects; oxidative stress; environmental health

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Plant Genomics and Genetics

edited by

Hengling Wei

submission deadline 15 Jul 2024 | 4 articles | Viewed by 3074

Keywords: plant genomics; plant genetics; abiotic stresses; salt resistance; genome; next-generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Approaches for Topical or Transdermal Delivery of Large Molecules

edited by Arvind Bagde and Shawn D Spencer

submission deadline 15 Jul 2024 | 1 articles | Viewed by 2953

Keywords: topical; insulin; proteins; antibodies; transdermal; microneedle

(This special issue belongs to the Section Molecular Pharmacology)

Leptin and Obesity Associated Diseases

edited by

Víctor Sánchez-Margalet

submission deadline 15 Jul 2024 | 2 articles | Viewed by 2531

Keywords: leptin; obesity; obesity-associated disease; inflammation

(This special issue belongs to the Section Molecular Biology)

A Molecular Perspective on the Genetics of Kidney Diseases

edited by Joaquim Calado

submission deadline 15 Jul 2024 | 3 articles | Viewed by 2430

Keywords: kidney; genetics; solute transport; genomics; inflammation; dysmetabolism

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Molecular Research on Neuroprotective Approaches to Stroke

edited by

Matteo Haupt

submission deadline 15 Jul 2024 | 2 articles | Viewed by 2274

Keywords: stroke; neuroprotection; neuroprotectants; neuroregeneration; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stem Cells: Physiological, Cellular and Molecular Mechanisms

edited by Elizabeth A. Blaber

submission deadline 15 Jul 2024 | 2 articles | Viewed by 2082

Keywords: stem cell function; iPSC; embryonic stem cells; somatic stem cells; pluripotency; differentiation; physiology; microenvironment; molecular regulation; cellular interactions

(This special issue belongs to the Section Molecular Biology)

The Role of Lysosomal Proteases in Cancer and Infectious Diseases

edited by

Christian Studenik

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1982

Keywords: cathepsins; lysosomes; apoptosis; autophagy; cancer; cell cycle; metastasis; molecular tumor pathology; radiation therapy; therapeutic targets; translational cancer research; treatment response; tumor microenvironment; viral infections

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Evolution, Genetics and Pathogenesis of Viruses

edited by

Marta Szabat

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1951

Keywords: viruses; genome structure; viral RNA/DNA; replication viral cycle; recombination; viral infection; antiviral agents

(This special issue belongs to the Section Molecular Microbiology)

Functional Genomics of Energy Crops 2.0

edited by Gongke Zhou

submission deadline 15 Jul 2024 | 2 articles | Viewed by 1861

Keywords: energy crops; high light efficiency; high biomass; lignocellulosic biomass; starch biomass; oil biomass; sugar biomass; biomass metabolism; transcriptional regulation; functional genomics; genetic engineering; breeding; biomass conversion; stress resistance; marginal land; bioenergy

(This special issue belongs to the Section Molecular Plant Sciences)

Tau Pathobiology in Neurodegenerative Diseases: From Molecular Mechanisms to Therapeutic Advances

edited by

Valentina Latina

and

Giuseppina Amadoro

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1802

Keywords: Alzheimer’ s disease; tauopathies; tau neurotoxicity; cellular and animal models; signaling pathways; tau-targeting therapies

(This special issue belongs to the Section Molecular Neurobiology)

Natural Antioxidants in Human Health and Disease, 2nd Edition

edited by

María Herranz-López

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1565

Keywords: ROS; oxidative disorders; molecular pathways; inflammation; biotransformation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

ER Stress, Mitochondrial Dysfunction, and Neuroinflammation in Neurodegenerative Diseases

edited by

Muhammad Hossain

and

Jason Cannon

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1476

Keywords: ER stress ; mitochondrial dysfunction ; neuroinflammation ; microglia ; astrocytes ; apotosis ; neurodegeneration ; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Cellular Intrinsic Modulators in the Pathogenesis of Cancer and Inflammatory Diseases

edited by

Kishu Ranjan

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1378

Keywords: cancer; immunobiology; chronic diseases; CRISPR; drug discovery; multi-omics

(This special issue belongs to the Section Molecular Oncology)

Targeting Collagen-Related Therapy

edited by Fernando Revert

submission deadline 15 Jul 2024 | 1 articles | Viewed by 1025

Keywords: collagen; extracellular matrix; molecular target; tissue engineering; drug deliver

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis, Properties and Biological Evaluation of Ferrocene-Modified Peptides and Biomolecules

edited by Lidija Barišić

submission deadline 15 Jul 2024 | 1 articles | Viewed by 822

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

New Progress in Extracellular Vesicles

edited by

Jorge Sanz-Ros

submission deadline 15 Jul 2024 | 1 articles | Viewed by 726

Keywords: extracellular vesicles; intercellular communication; biogenesis; uptake; disease pathogenesis; regenerative medicine; immunology; single-particle analysis

(This special issue belongs to the Section Molecular Biology)

Advances in Protein Tyrosine Phosphatases

edited by Alastair Barr

submission deadline 15 Jul 2024 | 1 articles | Viewed by 654

Keywords: PTPs; protein tyrosine phosphatases; signalling molecules; drug target; genetic mutation; post-translational modification; pharmacological applications; phosphate; phosphorylation

(This special issue belongs to the Section Molecular Pharmacology)

Heart Disease and Its Complications: From Molecular Mechanisms to Therapy

edited by

Chin-Feng Tsai

submission deadline 15 Jul 2024 | 1 articles | Viewed by 508

Keywords: cardiovascular disease; atherosclerosis; arrhythmia; heart failure; signal pathway; molecular/cellular mechanism; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Macroscopic and Microscopic Thermodynamics: From Fundamentals to Present Applications, 3rd Edition

edited by

Ana M. Mainar

and

José S. Urieta

submission deadline 15 Jul 2024 | Viewed by 440

Keywords: thermophysical properties; statistical thermodynamics; intermolecular forces; molecular models; applied thermodynamics; phase equilibria; transport across interfaces; process modeling; advanced separation processes

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Advances and New Insights in Organic Synthesis

edited by

Chien-Tien Chen

submission deadline 15 Jul 2024 | Viewed by 268

Keywords: green and bio-mimetic catalysis; organo-organometallic catalysis; light-responsive activation and/or release; bio-medicinal active; materials application; radical or NO directed

(This special issue belongs to the Section Biochemistry)

Isolation, Characterization and Application of Lignin

edited by Edita Jasiukaitytė-Grojzdek

submission deadline 15 Jul 2024 | Viewed by 256

Keywords: lignin; lignocellulose; renewable resources; biomass fractionation; lignin isolation; lignin fractionation; lignin valorization; biomaterials; biocomposites; biorefinery concept

(This special issue belongs to the Section Materials Science)

Athlete's Heart: From Cellular–Molecular Mechanism to Structural Anomalies

edited by

Daniela Miricescu

and

Maria Greabu

submission deadline 15 Jul 2024 | Viewed by 214

Keywords: physical activity; mitochondria; athlete’ s heart; cardiac myocytes; cardiac death; stress; metabolism; glucose; lipids; nutrients

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Proteasome Inhibition

edited by

Laura Ielo

submission deadline 15 Jul 2024 | Viewed by 189

Keywords: proteasome inhibitors; anti-proliferative activity; in vivo studies; in vitro studies; multiple myeloma; natural products; cancer; crystal structures

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Prostate Cancer Diagnostics and Therapy

edited by Benedikt Kranzbühler

submission deadline 20 Jul 2024 | 7 articles | Viewed by 10573 | Submission Open

Keywords: prostate cancer; molecular pathways; diagnostics; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Bioactive Glucosinolates and Derivatives

edited by

Gina Rosalinda De Nicola

submission deadline 20 Jul 2024 | 6 articles | Viewed by 9728 | Submission Open

Keywords: glucosinolate; isothiocyanate; myrosinase; Brassicales; chemical characterization; biological characterization; mechanism of action; stability; functionality; biopesticides; biostimulants; nutraceuticals

(This special issue belongs to the Section Bioactives and Nutraceuticals)

PD-L1, a Master Regulator of Immunity in Health and Disease

edited by

Grazyna Kochan

and

David Escors

submission deadline 20 Jul 2024 | 4 articles | Viewed by 9486 | Submission Open

Keywords: PD-1; PD-L1; T cell; immune checkpoint; myeloid cell; biomarker; cancer; auto-immunity; infectious disease

(This special issue belongs to the Section Biochemistry)

Neuroinflammatory Mediator in Neurodegenerative Disease

edited by

Laura Giannotti

and

Luisa Siculella

submission deadline 20 Jul 2024 | 6 articles | Viewed by 9398 | Submission Open

Keywords: neuroinflammation; pathogenesis; genotype; phenotype; neurodegenerative diseases; molecular mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

New Players in the Research of Oxidative Stress and Cancer

edited by

Ana Čipak Gašparović

submission deadline 20 Jul 2024 | 5 articles | Viewed by 9380 | Submission Open

Keywords: cancer; oxidative stress; biomarkes; redox signaling pathway; therapy resistance

(This special issue belongs to the Section Biochemistry)

Polyphenols and Their Impact on Human Health: 2nd Edition

edited by

Lucia Panzella

submission deadline 20 Jul 2024 | 4 articles | Viewed by 8363 | Submission Open

Keywords: polyphenols; antioxidants; food supplements; biomedical devices; skincare; agri-food by-products; sustainability

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Serum Albumin in Health and Disease: From Comparative Biochemistry to Translational Medicine 2.0

edited by

Nikolay V. Goncharov

Richard O. Jenkins

and

Daria Belinskaia

submission deadline 20 Jul 2024 | 6 articles | Viewed by 7605 | Submission Open

Keywords: albumin; oncotic pressure; (pseudo)esterase activity; molecular crowding; receptors and signaling; glycation; covalent adducts; oxidative stress; organophosphates; pharmacokinetics; toxicokinetics; diagnostics; metabolomics; therapy

(This special issue belongs to the Section Macromolecules)

Smart Plant Breeding Revealed by NGS Tools, Omics Approaches, and AI Technology

edited by

Manosh Biswas

submission deadline 20 Jul 2024 | 6 articles | Viewed by 6797 | Submission Open

Keywords: short read; long read; HI-C; genotyping-by-sequencing (GBS); genome-wide association studies (GWAS); population structure; genomic selection (GS); genetic diversity; molecular markers; in situ hybridizations; functional genomics; gene expression; bio-informatics; molecular breeding

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biological Functions and Therapeutic Applications of Extracellular Vesicles

edited by

Regina Golan-Gerstl

submission deadline 20 Jul 2024 | 4 articles | Viewed by 5200 | Submission Open

Keywords: miRNA; extracellular vesicles; exosomes; colitis

(This special issue belongs to the Section Molecular Biology)

Brassinosteroid (BR) Signal Transduction in Plants

edited by

Barbara Sawicka

submission deadline 20 Jul 2024 | 4 articles | Viewed by 5062 | Submission Open

Keywords: brassinosteroids; stress responses; phosphorylation; signaling pathways

(This special issue belongs to the Section Molecular Plant Sciences)

A Commemorative Issue Honoring Biomolecular Scientists in the Post-COVID-19 Pandemic Era

edited by

Michael Danquah

submission deadline 20 Jul 2024 | 4 articles | Viewed by 4926 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Advances in Skin Disease: Pathophysiological Mechanisms and Treatment Strategies

edited by Young Bok Lee

submission deadline 20 Jul 2024 | 4 articles | Viewed by 3514 | Submission Open

Keywords: acne; actinic keratosis; atopic dermatitis; Behcet’ s disease; bullous pemphigoid; hidradenitis suppurativa; rosacea; skin cancer; pemphigus; psoriasis; urticaria

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Compounds in Cancers

edited by

Patricia M. A. Silva

Honorina Cidade

and

Hassan Bousbaa

submission deadline 20 Jul 2024 | 3 articles | Viewed by 3411 | Submission Open

Keywords: anticancer strategies; bioactive compounds; natural products; synthetic products; medicinal chemistry; drug repurposing; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

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