Advances in Molecular Mechanisms of Neurodegenerative Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 1224
Special Issue Editor
Interests: neurodegeneration; proteostasis; neurodegenerative disorders; Parkinson’s disease; proteomic analysis; mitochondria; reactive oxygen species
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases affect millions of people worldwide and have been recognised as a critical global health challenge. Neurodegenerative diseases comprise multiple disorders including Parkinson’s and Alzheimer’s disease and are primarily characterised by a progressive loss of neurons. There are several approved drugs for managing neurodegenerative diseases; however, a majority of these drugs only target disease symptoms. At the cellular level, oxidative stress, mitochondrial dysfunction and altered proteolysis are considered important contributors to neurodegeneration. However, more research into molecular signalling mechanism is needed to better understand the complex nature and signalling molecules/pathways involved in neuronal death. This Special Issue is dedicated to the recent research progress made in unrevealing the molecular signalling mediating cell death and survival in neurodegeneration and identifying new targets/pathways that can be exploited for the development of novel therapies to stop/slow down neuronal death.
This Special Issue is supervised by Dr. Aslihan Ugun-Klusek and assisted by our Guest Editor’s Assistant Editor Dr. Shreyasi Chatterjee (Nottingham Trent University).
Dr. Aslihan Ugun-Klusek
Guest Editor
Manuscript Submission Information
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Keywords
- neurodegeneration
- Parkinson’s disease
- Alzheimer’s disease
- molecular signalling
- neuronal death
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