Head and Neck Oncologic Surgery: Clinical Updates and New Perspectives in Precision Medicine Era
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 4140
Special Issue Editors
Interests: head and neck oncology; middle ear surgery; laryngology; cochlear implant; microvascular reconstruction
2. Unit of Otorhinolaryngology, King’s College Hospital London-Dubai, Dubai P.O. Box 340901, United Arab Emirates
Interests: head and neck oncology; middle ear surgery; laryngology; cochlear implant; pediatric otorhinolaryngology; microvascular reconstruction
Special Issue Information
Dear Colleagues,
Head and neck cancer (HNC) is the seventh most common cancer globally, accounting for more than 660,000 new cases and 325,000 deaths annually. Approximately 90% of head and neck cancers are squamous cell carcinomas, which arise from the epithelial lining of the oral cavity, pharynx, and larynx.
The main treatment modalities for head and neck cancers include surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy. The size, location, and stage of the tumor, as well as metastasis status, are factors to be considered when determining operability and outcomes. Surgery is often the first-line treatment for localized head and neck cancers, and it may be used alone or in combination with other treatment modalities.
Multiple surgical approaches have been developed (such as transoral surgeries, open partial laryngectomies, tailored technology-assisted microvascular reconstruction, chemoradiotherapy protocols) with the aim of improving the survival of these patients and preserving or restoring their facial appearance, residual voice, ability to swallow and, consequently, quality of life to the best possible degree.
Surgical treatment may not be of benefit in patients with metastatic lesions, while radiotherapy and systemic therapy with pharmacologic agents may be better treatment options in these cases.
Precision medicine represents an emerging therapeutic approach focused on tailoring treatment for each individual patient. Despite the recent improvements in knowledge within this field, precision medicine-based therapies currently have a limited role in clinical practice. Clinical trials and studies based on precision medicine could improve the selection of the best treatment option for each patient and help to develop panels of markers that help to identify patients with high or low risks of recurrence or metastasis.
This Special Issue will focus on the functional and oncological outcomes of surgical strategies (with major interest in precision medicine trials) and organ preservation, as well as the reconstructive protocols applied to personalized medicine.
The following types of papers are welcome, including, but not limited to:
- Original articles;
- Clinical studies;
- Review articles;
- Translational research.
We are looking forward to receiving your manuscripts.
Dr. Filippo Carta
Prof. Dr. Roberto Puxeddu
Guest Editors
Manuscript Submission Information
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Keywords
- head and neck cancer
- squamous cell carcinoma
- free flap
- microsurgery
- oral cancer
- laryngeal cancer
- pharyngeal cancer
- skin cancer
- salivary gland cancer
- precision medicine
- personalized medicine
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