Viral and Bacterial Infection in People with Primary and Secondary Immunodeficiencies
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Infectious Diseases".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 3173
Special Issue Editor
Special Issue Information
Dear Colleagues,
We are living in challenging times in this globalized world in which brand new and reemerging viral and bacterial agents are quickly spreading. We invite you to contribute a manuscript on but not restricted to viral and bacterial, but also parasitic and fungal infectious diseases in patients with primary or secondary immunodeficiencies.
Primary immunodeficiencies (PID) or inborn errors of immunity (IEI) are a complex array of rare genetic diseases that result from one or more abnormalities of the immune system. There are about 485 PID. Worldwide, they are underdiagnosed and present clinically as increased susceptibility to infections, autoimmunity, autoinflammatory diseases, allergy, bone marrow failure, and/or malignancy. Secondary immunodeficiencies (SID) are impairment of the immune system due to extrinsic factors, underlying medical conditions including hematological malignancy and rheumatic diseases, or medication. SID is up to 30 times more common than PID and is becoming increasingly common as new therapies are available. As in PID, in SID, viral infections can produce severe diseases if not diagnosed early and treated. On the other hand, bacterial infections are prevalent and are a significant cause of morbidity and a leading cause of mortality in both groups. They require multidisciplinary awareness and an approach to identification and management. The construction of protocols and sharing of information and experiences for the diagnosis and treatment of these infections constitute essential tools that enable practitioners to integrate and collaborate successfully to deliver improved outcomes for patients with PID or SID.
Dr. Luiz Euribel Prestes Carneiro
Guest Editor
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Keywords
- primary immunodeficiencies
- secondary immunodeficiencies
- viral–bacterial infections
- diagnosis and treatment
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