Highlights in Infective Endocarditis

Dear Colleagues,

Infective endocarditis (IE) is a life-threatening disease resulting from an infection of the endocardial lining of the heart, prosthetic valve, or indwelling cardiac device [1]. The incidence of IE has been increasing globally in recent decades, and the annual increasing trend was more evident for people over 60 years of age, especially in developed countries [2]. Elderly people with IE are at a much greater risk of mortality, ranging at 24.9%, which is almost twice as high as in younger groups [3]. The population of older patients is characterized by a greater heterogeneity regarding their functional abilities, cognition, nutritional status, and comorbidities [4]. Considering the increased risks of cardiac, renal, neurological, lung, and rheumatological complications in patients due to IE, establishing multidisciplinary endocarditis teams according to the European Society of Cardiology and the American College of Cardiology/American Heart Association Guidelines since 2023 has resulted in earlier and more accurate diagnoses. We wish to read the experience of our community of IE management. We believe that our readers are eager to read the epidemiology, etiology, diagnosis, and management considerations of IE. We need to change the scenario of morbidity and mortality in this cardiovascular infection, and that is our mission in this project. Hence, we will address all participation in this Special Issue, in which the topic is the highlights in the management of people with IE. We invite submissions from infectious disease physicians, microbiolgists, epidemiologists, cardiologists, cardiac surgeons, geriatricians, pharmacists, and radiologists to contribute with comprehensive or sytematic reviews and original articles, case reports, and short communications with regard to highlights for people with infective IE. Articles are submitted for peer review and are subject to processing charges.

References

1. Holland, T.L.; Baddour, L.M.; Bayer, A.S.; Hoen, B.; Miro, J.M.; Fowler, V.G., Jr. Infective endocarditis. Nat. Rev. Dis. Primers 2016, 2, 16059. https://doi.org/10.1038/nrdp.2016.59.
2. Yang, X.; Chen, H.; Zhang, D.; Shen, L.; An, G.; Zhao, S. Global magnitude and temporal trend of infective endocarditis, 1990–2019: Results from the Global Burden of Disease Study. Eur. J. Prev. Cardiol. 2022, 8, 1277–1286. https://doi.org/10.1093/eurjpc/zwab184.
3. Durante-Mangoni, E.; Bradley, S.; Selton-Suty, C.; Tripodi, M.F.; Barsic, B.; Bouza, E.; Cabell, C.H.; de Oliveira Ramos, A.I.; Fowler, V., Jr.; Hoen, B.; et al. Current features of infective endocarditis in elderly patients: Results of the International Collaboration on Endocarditis Prospective Cohort Study. Arch. Intern. Med. 2008, 19, 2095–2103. https://doi.org/10.1001/archinte.168.19.2095.
4. Forestier, E.; Roubaud-Baudron, T.; Fraisse, T.; Patry, C.; Gavazzi, G.; Hoen, B.; Carauz-Paz, P.; Moheb-Khosravi, B.; Delahaye, F.; Sost, G.; et al. AEPEI and the GInGer Elderl-IE study group. Comprehensive geriatric assessment in older patients suffering from infective endocarditis. A prospective multicentric cohort study. Clin. Microbiol. Infect. 2019, 10, 1246–1252. https://doi.org/10.1016/j.cmi.2019.04.021.

Prof. Dr. Paulo Vieira Damasco
Dr. Rinaldo Focaccia Siciliano
Guest Editors

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• highlights in infective endocarditis
• management of infective endocarditis
• infective endocarditis in personalized medicine
• highlights in the elderly with infective endocarditis
• experience of managing infective endocarditis
• microbiological diagnosis
• cardiac surgery
• cardiac devices