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13 pages, 11521 KiB  
Case Report
Juvenile Osteochondritis Dissecans: A Case Report
by Hermann Nudelman, Aba Lőrincz, Tamás Kassai and Gergő Józsa
Diagnostics 2024, 14(17), 1931; https://doi.org/10.3390/diagnostics14171931 - 1 Sep 2024
Viewed by 306
Abstract
(1) Background: This report aims to illustrate the development, progression, diagnosis, and treatment of chronically present articular surface lesions. (2) Methods: In this report, two patients are described from the point of the initial presentation of symptoms to surgical consultation based on radiologic [...] Read more.
(1) Background: This report aims to illustrate the development, progression, diagnosis, and treatment of chronically present articular surface lesions. (2) Methods: In this report, two patients are described from the point of the initial presentation of symptoms to surgical consultation based on radiologic findings. These patients underwent corrective surgery in the form of mosaicplasty to repair lesions present on the articular surface and the underlying subchondral bone. (3) Discussion: Diagnosing juvenile OCD remains challenging due to its variable clinical presentation and minute radiologic discoveries. X-rays are useful; however, the gold standard remains arthroscopy, which can be both diagnostic and therapeutic. Future prospects include the use of novel sonographic methods and the use of artificial intelligence within the given modalities. (4) Conclusions: The detailed imaging provided by MRI, combined with the insights from X-rays and potentially other modalities, allows for a nuanced understanding of this disease. This comprehensive approach ensures that treatment decisions are well-informed, optimising outcomes for young patients with this condition. Full article
(This article belongs to the Special Issue Critical Issues in Diagnosis and Management of Pediatric Diseases)
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13 pages, 676 KiB  
Article
Health-Related Physical Fitness and Biochemical Parameters in Overweight Older People during Social Isolation Imposed by the COVID-19 Pandemic: A Longitudinal and Observational Study
by Marilene Ghiraldi de Souza Marques, Braulio Henrique Magnani Branco, Déborah Cristina de Souza Marques, Marielle Priscila de Paula Silva Lalucci, Victor Augusto Santos Perli, José Roberto Andrade do Nascimento, Pablo Valdés-Badilla and Daniel Vicentini de Oliveira
Int. J. Environ. Res. Public Health 2024, 21(9), 1161; https://doi.org/10.3390/ijerph21091161 - 31 Aug 2024
Viewed by 309
Abstract
With COVID-19, evidence indicates that the elderly will have worse biochemical markers related to health in social isolation. The objective was to analyze the impacts on physical fitness and biochemical parameters of older adults’ health during COVID-19 social isolation. Quantitative, longitudinal, and observational [...] Read more.
With COVID-19, evidence indicates that the elderly will have worse biochemical markers related to health in social isolation. The objective was to analyze the impacts on physical fitness and biochemical parameters of older adults’ health during COVID-19 social isolation. Quantitative, longitudinal, and observational study was conducted between 2020, 2021, and 2022. Thirty-three older adults of both sexes were evaluated. A sociodemographic questionnaire, biomarkers, and health-related physical fitness were used. Significant differences were observed for the sum of maximum isometric right and left handgrip strength, with a reduction in 2022 (p = 0.009); getting up and walking (p < 0.001), reduction in 2021 and 2022 (p < 0.05); elbow flexion and extension (p = 0.004), reduction in 2021 (p = 0.006); and sitting and standing (p = 0.002), reduction in 2022 (p = 0.003) and peak oxygen consumption (p < 0.001), reduction in 2021 and 2022 (p < 0.05). Differences were observed in fasting blood glucose (p < 0.001), with increase in 2021 and 2022 (p < 0.05), triglycerides (p < 0.001), with increase in 2021 and 2022 (p < 0.05), triglyceride–glucose index (p < 0.001), with increase in 2021 and 2022 (p < 0.05), triglyceride–glucose index with waist circumference (p < 0.001), with increase in 2021 (p < 0.001); and triglyceride–glucose index with body mass index (p < 0.001), with increase in 2021 (p < 0.001). However, no differences were observed between anthropometric and body composition (p > 0.05). Conclusions: Older people had changes in biochemical and physical fitness parameters related to health during the social isolation of the COVID-19 pandemic. Full article
(This article belongs to the Section Exercise and Health-Related Quality of Life)
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11 pages, 1388 KiB  
Article
Clinical, Radiographic, and Biomechanical Evaluation of the Upper Extremity in Patients with Osteogenesis Imperfecta
by Katharina Oder, Fabian Unglaube, Sebastian Farr, Andreas Kranzl, Alexandra Stauffer, Rudolf Ganger, Adalbert Raimann and Gabriel T. Mindler
J. Clin. Med. 2024, 13(17), 5174; https://doi.org/10.3390/jcm13175174 - 31 Aug 2024
Viewed by 269
Abstract
Introduction: Osteogenesis imperfecta (OI) is a hereditary disorder primarily caused by mutations in type I collagen genes, resulting in bone fragility, deformities, and functional limitations. Studies on upper extremity deformities and associated functional impairments in OI are limited. This cross-sectional study aimed to [...] Read more.
Introduction: Osteogenesis imperfecta (OI) is a hereditary disorder primarily caused by mutations in type I collagen genes, resulting in bone fragility, deformities, and functional limitations. Studies on upper extremity deformities and associated functional impairments in OI are limited. This cross-sectional study aimed to evaluate upper extremity deformities and functional outcomes in OI. Methods: We included patients regardless of their OI subtypes with a minimum age of 7 years. Radiographic analysis of radial head dislocation, ossification of the interosseous membrane, and/or radioulnar synostosis of the forearm were performed, and deformity was categorized as mild, moderate, or severe. Clinical evaluation was performed using the Quick Disabilities of Arm, Shoulder, and Hand (qDASH) questionnaire and shoulder-elbow-wrist range of motion (ROM). Three-dimensional motion analysis of the upper limb was conducted using the Southampton Hand Assessment Procedure (SHAP). The SHAP quantifies execution time through the Linear Index of Function (LIF) and assesses the underlying joint kinematics using the Arm Profile Score (APS). Additionally, the maximum active Range of Motion (aRoM) was measured. Results: Fourteen patients aged 8 to 73 were included. Radiographic findings revealed diverse deformities, including radial head dislocation, interosseous membrane ossification, and radioulnar synostosis. Six patients had mild, six moderate, and two severe deformities of the upper extremity. Severe deformities and radial head dislocation correlated with compromised ROM and worse qDASH scores. The qDASH score ranged from 0 to 37.5 (mean 11.7). APS was increased, and LIF was reduced in OI-affected persons compared with non-affected peers. APS and LIF also varied depending on the severity of bony deformities. aRoM was remarkably reduced for pro-supination. Conclusion: Patients with OI showed variable functional impairment from almost none to severe during daily life activities, mainly depending on the magnitude of deformity in the upper extremity. Larger multicenter studies are needed to confirm the results of this heterogeneous cohort. Level of evidence: Retrospective clinical study; Level IV. Full article
(This article belongs to the Special Issue Challenges in Hand and Upper Limb Surgery)
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17 pages, 7390 KiB  
Article
Pipeline Elbow Corrosion Simulation for Strain Monitoring with Fiber Bragg Gratings
by Kaimin Yu, Zixuan Peng, Yuanfang Zhang, Peibin Zhu, Wen Chen and Jianzhong Hao
Micromachines 2024, 15(9), 1098; https://doi.org/10.3390/mi15091098 (registering DOI) - 29 Aug 2024
Viewed by 261
Abstract
This study addresses the limitation of traditional non-destructive testing methods in real-time corrosion monitoring of pipe elbows by proposing the utilization of fiber Bragg grating (FBG) strain sensors, renowned for their resilience in harsh environments. However, the current mathematical relationship model for strain [...] Read more.
This study addresses the limitation of traditional non-destructive testing methods in real-time corrosion monitoring of pipe elbows by proposing the utilization of fiber Bragg grating (FBG) strain sensors, renowned for their resilience in harsh environments. However, the current mathematical relationship model for strain representation of elbow corrosion is still lacking. This paper develops a finite element model to scrutinize the strain changes in the elbow due to corrosion under hydrostatic pressure and bending loads. To mitigate temperature loading effects, the corrosion degree is evaluated through the disparity between hoop and axial strains. Simulation outcomes reveal that, under hydrostatic pressure, the strain difference exhibits minimal changes with the increase in corrosion degree, while under bending moment loading, the strain difference escalates proportionally with corrosion progression. Consequently, strain induced by bending moment loading solely characterizes the corrosion degree. Moreover, the optimal placement for FBG sensors is identified at the extrados of the pipe elbow, where strain is most prominent. These insights enhance comprehension of strain–corrosion dynamics in pipe elbows, offering valuable guidance for developing an FBG-based monitoring system for real-time corrosion tracking and predictive maintenance of pipeline infrastructures. Full article
(This article belongs to the Special Issue Precision Optical Manufacturing and Processing)
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22 pages, 10563 KiB  
Article
Low-Cost Cable-Driven Robot Arm with Low-Inertia Movement and Long-Term Cable Durability
by Van Pho Nguyen, Wai Tuck Chow, Sunil Bohra Dhyan, Bohan Zhang, Boon Siew Han and Hong Yee Alvin Wong
Robotics 2024, 13(9), 128; https://doi.org/10.3390/robotics13090128 - 27 Aug 2024
Viewed by 573
Abstract
Our study presents a novel design for a cable-driven robotic arm, emphasizing low cost, low inertia movement, and long-term cable durability. The robotic arm shares similar specifications with the UR5 robotic arm, featuring a total of six degrees of freedom (DOF) distributed in [...] Read more.
Our study presents a novel design for a cable-driven robotic arm, emphasizing low cost, low inertia movement, and long-term cable durability. The robotic arm shares similar specifications with the UR5 robotic arm, featuring a total of six degrees of freedom (DOF) distributed in a 1:1:1:3 ratio at the arm base, shoulder, elbow, and wrist, respectively. The three DOF at the wrist joints are driven by a cable system, with heavy motors relocated from the end-effector to the shoulder base. This repositioning results in a lighter cable-actuated wrist (weighing 0.8 kg), which enhances safety during human interaction and reduces the torque requirements for the elbow and shoulder motors. Consequently, the overall cost and weight of the robotic arm are reduced, achieving a payload-to-body weight ratio of 5:8.4 kg. To ensure good positional repeatability, the shoulder and elbow joints, which influence longer moment arms, are designed with a direct-drive structure. To evaluate the design’s performance, tests were conducted on loading capability, cable durability, position repeatability, and manipulation. The tests demonstrated that the arm could manipulate a 5 kg payload with a positional repeatability error of less than 0.1 mm. Additionally, a novel cable tightener design was introduced, which served dual functions: conveniently tightening the cable and reducing the high-stress concentration near the cable locking end to minimize cable loosening. When subjected to an initial cable tension of 100 kg, this design retained approximately 80% of the load after 10 years at a room temperature of 24 °C. Full article
(This article belongs to the Section Industrial Robots and Automation)
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10 pages, 3920 KiB  
Article
Glenolabral Articular Disruption (GLAD) Is Not Associated with Worse Outcomes or Higher Instability Recurrence after Arthroscopic Bankart Repair—A Matched-Pair Analysis
by Romed P. Vieider, Sebastian Siebenlist, Jose C. Sanchez, Selina Heil, Anja Wackerle, Lorenz Fritsch, Bastian Scheiderer, Maximilian Hinz and Lucca Lacheta
J. Clin. Med. 2024, 13(17), 5067; https://doi.org/10.3390/jcm13175067 - 27 Aug 2024
Viewed by 324
Abstract
Background: This study aimed to compare clinical outcomes and recurrence of instability after arthroscopic Bankart repair (ABR) in patients with anterior shoulder instability, with and without a GLAD lesion, while distinguishing between primary and recurrent instability. Methods: Consecutive patients who underwent isolated ABR [...] Read more.
Background: This study aimed to compare clinical outcomes and recurrence of instability after arthroscopic Bankart repair (ABR) in patients with anterior shoulder instability, with and without a GLAD lesion, while distinguishing between primary and recurrent instability. Methods: Consecutive patients who underwent isolated ABR between January 2012 and December 2021 were included. Patients with a concomitant GLAD lesion were matched in with patients without a GLAD lesion according to the following criteria: age, sex, BMI, follow-up time, and primary versus recurrent instability. At minimum two-year follow-up, the clinical outcome (Rowe score, redislocation rate) and the functional outcome, including the American Shoulder and Elbow Surgeons (ASES) score, Western Ontario Shoulder Instability Index (WOSI), Oxford Shoulder Instability Score (OSIS), satisfaction (1–10 scale, 0 = unsatisfied, 10 = very satisfied), and Visual Analogue Scale (VAS), were compared between groups. Results: In total, 28 patients (14 GLAD vs. 14 Bankart; age: 32.5 ± 13.0 years; sex: 92.9% male; BMI: 24.6 ± 2.2) were included 6.9 ± 2.8 (2–11) years after isolated ABR (follow-up rate 63.6%). Clinical and functional outcome did not differ significantly between patients with versus without GLAD lesions (ASES score: 100 [96.5–100] vs. 97.5 [93.3–100], p = 0.27); WOSI (%): 9.0 [3.7–24.5] vs. 3.8 [0.8–8.9], p = 0.22; Rowe score: 90.0 [75.0–100] vs. 95.0 [78.8–100], p = 0.57; OSIS: 46 [44.7–48] vs. 46 [43.0–48], p = 0.54; satisfaction: 8.9 ± 1.4 vs. 8.0 ± 1.4, p = 0.78; VAS 0 [0–1.3] vs. 0 [0–1.0]. In both groups, two patients (14.3%) reported a redislocation during the observation period. Conclusions: At short- to mid-term follow-up, ABR showed favorable outcomes, low dislocation rates, and high patient satisfaction, regardless of the presence of a GLAD lesion or primary versus recurrent instability. However, follow-up time was heterogeneous, and the follow-up rate was marginal. Full article
(This article belongs to the Special Issue Advances in Shoulder Surgery)
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13 pages, 3029 KiB  
Article
Demographic-, Radiographic-, and Surgery-Related Factors Do Not Affect Functional Internal Rotation Following Reverse Total Shoulder Arthroplasty: A Retrospective Comparative Study
by Felix Hochberger, Jakob Siebler, Marco-Christopher Rupp, Bastian Scheiderer, Sebastian Siebenlist and Stephanie Geyer
Healthcare 2024, 12(17), 1695; https://doi.org/10.3390/healthcare12171695 - 26 Aug 2024
Viewed by 366
Abstract
Purpose: This study aimed to identify the demographic-, radiographic-, and surgery-related factors influencing postoperative functional internal rotation (fIR) following reverse total shoulder arthroplasty (RTSA). Methods: In this retrospective cohort study, patients who underwent RTSA between June 2013 and April 2018 at a single [...] Read more.
Purpose: This study aimed to identify the demographic-, radiographic-, and surgery-related factors influencing postoperative functional internal rotation (fIR) following reverse total shoulder arthroplasty (RTSA). Methods: In this retrospective cohort study, patients who underwent RTSA between June 2013 and April 2018 at a single institution were assigned to two groups (“IROgood” or “IRObad”). Patients were classified as having good fIR (≥8 points in the Constant–Murley score (CS) and fIR to the twelfth thoracic vertebra or higher) or poor fIR (≤2 points in the CS and fIR to the twelfth thoracic vertebra or lower) after RTSA with a single implant model. The minimum follow-up period was two years. Standardized shoulder-specific scores (Visual Analogue Scale (VAS), Simple Shoulder Test (SST), American Shoulder and Elbow Surgeons Score (ASES), Constant–Murley score (CS)) were used to assess the pre- and postoperative functional status of patients. Postoperative radiographic evaluation included the distalization shoulder angle (DSA), lateralization shoulder angle (LSA), critical shoulder angle (CSA), acromiohumeral distance (AHD), glenoid inclination (GI), medialization of the center of rotation (COR), lateralization of the humerus, and distalization of the greater tuberosity. Additionally, preoperative evaluation included rotator cuff arthropathy according to Hamada, glenoid version, anterior or posterior humeral head subluxation, and fatty infiltration of the rotator cuff according to Goutallier. Univariate analysis of demographic, surgical, radiographic, and implant-associated parameters was performed to identify factors associated with postoperative fIR. The Shapiro–Wilk test assessed the normal distribution of the data. Intergroup comparisons regarding demographic and surgery-related factors were conducted using the Mann–Whitney-U Test. Radiographic changes were compared using chi-square or Fisher’s exact tests. The significance level was set at p < 0.05. Results: Of a total of 42 patients, 17 (age: 73.7 ± 5.0 years, follow-up (FU) 38 months [IQR 29.5–57.5]) were included in the “IRObad” group, and 25 (age: 72 ± 6.1 years, FU 47 months [IQR 30.5–65.5]) were included in the “IROgood” group. All patients were treated with the same type of implant (glenosphere size: 36 mm, 14.3%; 39 mm, 38.1%; 42 mm, 47.6%; neck-shaft angle: 135° in 68.0%; 155° in 32.0%) and had comparable indications. Univariate analysis did not reveal any of the investigated demographic, radiographic, or surgery-related parameters as risk factors for poor postoperative fIR (p > 0.05). Conclusion: None of the investigated factors, including implant-associated parameters, influenced postoperative fIR after RTSA in this cohort. Full article
(This article belongs to the Special Issue Health Service Interventions in Musculoskeletal Disorders)
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17 pages, 10823 KiB  
Article
Logging Identification Method for Reservoir Facies in Fractured-Vuggy Dolomite Reservoirs Based on AI: A Case Study of Ediacaran Dengying Formation, Sichuan Basin, China
by Yu Ye, Zengzheng Jiang, Xiangjun Liu, Zhanlei Wang and Yifan Gu
Appl. Sci. 2024, 14(17), 7504; https://doi.org/10.3390/app14177504 - 25 Aug 2024
Viewed by 435
Abstract
As an important target for deep to ultra-deep carbonate oil and gas exploration, Fractured-Vuggy dolomite reservoirs have strong heterogeneity. Accurate characterization of reservoir facies is crucial for their exploration and exploitation. Three methods, including the unsupervised intelligent clustering method of improved Fuzzy C-means [...] Read more.
As an important target for deep to ultra-deep carbonate oil and gas exploration, Fractured-Vuggy dolomite reservoirs have strong heterogeneity. Accurate characterization of reservoir facies is crucial for their exploration and exploitation. Three methods, including the unsupervised intelligent clustering method of improved Fuzzy C-means clustering Algorithm Based on Density Sensitive Distance and Fuzzy Partrition (FCM-DSDFP), the fusion method of Principal Components Analysis (PCA) dimensionality reduction and noise reduction, and the principle of clustering feature analysis are applied to identify reservoir facies based on logging data. Based on the PCA method, the logging response characteristics of the reservoir facies are excavated, and the fusion characterization data of dimensionality reduction and noise reduction are extracted. The FCM-DSDFP unsupervised intelligent clustering method, a model that approximates the subsurface conditions is established, and the reliability of the model is tested according to the elbow rule and silhouette coefficient. Combining drilling core observation, Fractured-Vuggy type, partially cemented Fractured-Vuggy type, Pore-Vuggy type, Pore Type I, Pore Type II, Tight Type I, and Tight Type II are divided in the Dengying Formation 4th Member. Fractured-Vuggy type, partially cemented Fractured-Vuggy type, Pore-Vuggy Type I, Pore-Vuggy Type II, Pore Type I, Pore Type II, and Tight Type are divided in the Dengying Formation 2nd Member, respectively. Two methods were applied to verify the reservoir facies identification results based on intelligent algorithms. The first method is to compare the identification results with the reservoir facies types identified by core observations (Well PT103 and PS13). The second method is to verify the recognition results of intelligent algorithms by utilizing the relationship between reservoir facies types and bitumen. The test results show that the accuracy of the reservoir level identification is higher than 0.9, and the applicability is better than the commonly used algorithms such as FCM and K-means. Full article
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12 pages, 1572 KiB  
Article
Investigation of Neuromuscular Activation in Older Female Adults during a Dynamic and Challenging Virtual Reality Activity: A Cross-Sectional Study
by Konstantina Intziegianni, Marc Sarens, Olia Tsivitanidou, Louis Nisiotis, Katalin Kovacs, Eniko Nagy and Efstathios Christodoulides
J. Funct. Morphol. Kinesiol. 2024, 9(3), 143; https://doi.org/10.3390/jfmk9030143 - 24 Aug 2024
Viewed by 543
Abstract
The use of virtual reality (VR) in older adults promotes improvements in mobility, strength, and balance. Changes in neuromuscular activation have been found to be associated with these improvements; however, during VR activities, this aspect has not been thoroughly investigated. The aim of [...] Read more.
The use of virtual reality (VR) in older adults promotes improvements in mobility, strength, and balance. Changes in neuromuscular activation have been found to be associated with these improvements; however, during VR activities, this aspect has not been thoroughly investigated. The aim of this study was to investigate neuromuscular activation among older female adults during VR activities. Sixteen older female adults, with the use of VR, performed dynamic punching movements involving elbow flexion/extension for one minute, and the muscle activation of the bicep brachii was recorded with electromyography (EMG) and normalized to the maximal voluntary isometric contraction of elbow flexion. The one-minute activity was divided into three time phases: 0–10 s, 25–35 s, and 50–60 s. The five highest EMG amplitude values (%) in each phase were selected and averaged. Differences between phases were analyzed using repeated ANOVA (αadj = 0.017). The EMG amplitude for the first phase was 39.1 ± 2.6%, that for the second phase was 44.8 ± 3.0%, and that for the third phase was 49.6 ± 3.1%. Statistically significant differences were found in all phases, with the first phase demonstrating a lower EMG amplitude (%) compared to the second (p = 0.002) and third phases (p = 0.000). The third phase demonstrated a higher EMG amplitude (%) compared to the second phase (p = 0.025). Engagement in VR activities can have significant effects on neuromuscular activation in older female adults, with our findings revealing a significant increase in the EMG amplitude within one minute of commencing a dynamic and challenging activity such as virtual boxing. Full article
(This article belongs to the Special Issue Physical Activity for Optimal Health)
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17 pages, 11701 KiB  
Article
Experimental Flow Performance Investigation of Francis Turbines from Model to Prototype
by Baig Mirza Umar, Xingxing Huang and Zhengwei Wang
Appl. Sci. 2024, 14(17), 7461; https://doi.org/10.3390/app14177461 - 23 Aug 2024
Viewed by 374
Abstract
Investigating the flow performance of Francis turbines from model to prototype is a complex but essential process for ensuring reliable and efficient turbine operation in hydropower plants. It ensures that Francis turbine designs operate efficiently under various operating conditions, extending from laboratory reduced-scale [...] Read more.
Investigating the flow performance of Francis turbines from model to prototype is a complex but essential process for ensuring reliable and efficient turbine operation in hydropower plants. It ensures that Francis turbine designs operate efficiently under various operating conditions, extending from laboratory reduced-scale models to full-scale prototype installations. In this investigation, a Francis turbine model was tested under different operating conditions, and its properties were measured, including torque, hydraulic efficiency, power output, cavitation coefficient, rotational speed, flow rate, and pressure pulsations. The results of the Francis turbine model test indicate that it achieved the maximum torque with the designed discharge and designed head. The cavitation coefficient consistently remained higher than the critical cavitation coefficient. The initial cavitation bubbles were observed at 50% partial load but disappeared at full load. Pressure pulsations under different operating conditions showed the maximum peak-to-peak amplitude appearing at the turbine inlet domain and the minimum amplitude occurring at the draft tube elbow. A hill chart shows that the model’s best efficiency was 93.66%, and the estimated best efficiency of the prototype was 95.03% at the design head. The conclusions and methodology of this study can be generalized to other similar hydraulic turbines, especially prototype Francis turbines that lack experimental results. Full article
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14 pages, 4926 KiB  
Article
Eight-Bar Elbow Joint Exoskeleton Mechanism
by Giorgio Figliolini, Chiara Lanni, Luciano Tomassi and Jesús Ortiz
Robotics 2024, 13(9), 125; https://doi.org/10.3390/robotics13090125 (registering DOI) - 23 Aug 2024
Viewed by 314
Abstract
This paper deals with the design and kinematic analysis of a novel mechanism for the elbow joint of an upper-limb exoskeleton, with the aim of helping operators, in terms of effort and physical resistance, in carrying out heavy operations. In particular, the proposed [...] Read more.
This paper deals with the design and kinematic analysis of a novel mechanism for the elbow joint of an upper-limb exoskeleton, with the aim of helping operators, in terms of effort and physical resistance, in carrying out heavy operations. In particular, the proposed eight-bar elbow joint exoskeleton mechanism consists of a motorized Watt I six-bar linkage and a suitable RP dyad, which connects mechanically the external parts of the human arm with the corresponding forearm by hook and loop velcro, thus helping their closing relative motion for lifting objects during repetitive and heavy operations. This relative motion is not a pure rotation, and thus the upper part of the exoskeleton is fastened to the arm, while the lower part is not rigidly connected to the forearm but through a prismatic pair that allows both rotation and sliding along the forearm axis. Instead, the human arm is sketched by means of a crossed four-bar linkage, which coupler link is considered as attached to the glyph of the prismatic pair, which is fastened to the forearm. Therefore, the kinematic analysis of the whole ten-bar mechanism, which is obtained by joining the Watt I six-bar linkage and the RP dyad to the crossed four-bar linkage, is formulated to investigate the main kinematic performance and for design purposes. The proposed algorithm has given several numerical and graphical results. Finally, a double-parallelogram linkage, as in the particular case of the Watt I six-bar linkage, was considered in combination with the RP dyad and the crossed four-bar linkage by giving a first mechanical design and a 3D-printed prototype. Full article
(This article belongs to the Section Neurorobotics)
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12 pages, 5166 KiB  
Article
Treatment of Chronic Haemophilic Synovitis with PRP: Clinical and In Vitro Studies
by Horacio Caviglia, María Eulalia Landro, Paula Oneto, Guillermo Cambiaggi, Gustavo Galatro, Micaela Berni, Laura Caliogna, Eugenio Antonio Carrera Silva and Gianluigi Pasta
Int. J. Mol. Sci. 2024, 25(17), 9140; https://doi.org/10.3390/ijms25179140 - 23 Aug 2024
Viewed by 243
Abstract
Intra-articular blood, iron and hemosiderin, hydroxyl radical cytokines, and neo-angiogenesis cause synovial inflammation, which leads to cartilage and joint damage. Platelet-rich plasma (PRP) inhibits most of the mediators that produce and maintain synovitis. We compile here our work showing the clinical effectiveness of [...] Read more.
Intra-articular blood, iron and hemosiderin, hydroxyl radical cytokines, and neo-angiogenesis cause synovial inflammation, which leads to cartilage and joint damage. Platelet-rich plasma (PRP) inhibits most of the mediators that produce and maintain synovitis. We compile here our work showing the clinical effectiveness of intra-articular PRP injections and their potential role in stopping articular cartilage damage due to bleeding and its possible repair. A total of 116 joints, including knees (63%), elbows (19.8%), and ankles (17.2%), were treated with intra-articular injections of PRP. Moreover, we also show here the number of extracellular DNA traps (ETs) and the PRP effect in the synovial fluid of patients at the time of treatment and six months after. Clinically, it is demonstrated that PRP is effective in reducing bleeding episodes (p < 0.001) and pain (p < 0.0001) and improving the hemophilia joint health score (HJHS) (p < 0.001) at one year of follow-up. Furthermore, our results demonstrate that PRP inhibits ET formation in vitro and reconstitutes the immune system’s cellular components in the synovial fluid of patients after treatment. We conclude that PRP can be considered an effective, safe, and easy treatment for hemophilic synovitis. Full article
(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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11 pages, 1112 KiB  
Article
Distal Triceps Tendon Repair in Strength Athletes Leads to Satisfactory Return to Sports: A Retrospective Analysis of 22 Cases
by Michael Stephan Gruber, Martin Bischofreiter, Felix Rittenschober, Michael Schachermayr, Reinhold Ortmaier and Mathias Ritsch
J. Clin. Med. 2024, 13(16), 4913; https://doi.org/10.3390/jcm13164913 - 20 Aug 2024
Viewed by 476
Abstract
Background: Distal triceps brachii tendon rupture (DTTR) is a relatively rare injury that is common in bodybuilding and high-intensity contact sports and can lead to significant functional impairment of the elbow joint. This study was conducted to evaluate clinical outcomes and the [...] Read more.
Background: Distal triceps brachii tendon rupture (DTTR) is a relatively rare injury that is common in bodybuilding and high-intensity contact sports and can lead to significant functional impairment of the elbow joint. This study was conducted to evaluate clinical outcomes and the rate of return to sports among competitive bodybuilders and high-demand strength athletes after surgical repair of DTTR. Methods: This retrospective case series was performed in an institutional setting in tertiary health care. Return to sports of 22 competing or high-demand strength athletes (meaning three or more exercises per week) were analyzed pre- and postoperatively after surgical repair of DTTR using a hybrid technique of transosseous sutures and anchor fixation. Descriptive statistics were used to analyze demographic variables, and independent and paired t-tests were used to assess clinical outcomes. Results: The follow-up showed that from pre- to postoperatively, there was no deterioration in the number of sports disciplines (2.4 and 2.5 sporting activities per person, respectively; p = 0.540) or in the frequency of weekly training (4.1 and 4.1 times per person, respectively; p = 0.329). The postoperative visual analog scale for pain (from 6.0 to 1.6, p < 0.001), level of fitness (from 5.1 to 2.6, p = 0.002), and ability to train (from 5.2 to 1.3, p < 0.001) improved significantly. The time of return to sports was 1.5–3 months and 4–6 months after the surgery for ten patients each. The overall rate of return to sports was 95%, whereas 86% returned to the preinjury level of sporting activity. Conclusions: Repair of DTTR leads to high rates of return to sports in competitive athletes. Full article
(This article belongs to the Special Issue Clinical Aspects of Return to Sport after Injuries)
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12 pages, 229 KiB  
Article
Functional Impact of Early Prosthetic Implantation in Children with Upper Limb Agenesis or Amputation
by Nicola Manocchio, Marco Gaudenzi, Marco Tofani, Concetta Ljoka, Anila Imeshtari, Laura Giordani, Gessica Della Bella and Calogero Foti
Appl. Sci. 2024, 14(16), 7259; https://doi.org/10.3390/app14167259 - 18 Aug 2024
Viewed by 553
Abstract
This study investigated the impact of early prosthetic intervention on children with upper limb agenesis or amputation. The aim was to assess both how early prosthetics improve a child’s movement and coordination skills, as well as how satisfied both the child and their [...] Read more.
This study investigated the impact of early prosthetic intervention on children with upper limb agenesis or amputation. The aim was to assess both how early prosthetics improve a child’s movement and coordination skills, as well as how satisfied both the child and their parents are with the prosthesis. Twenty-nine children were evaluated using the Unilateral Below Elbow Test (UBET) and Child Amputee Prosthetics Project—Prothesis Satisfaction Inventory (CAPP-PSI). Results suggest that while children performed tasks faster and more fluidly without a prosthesis, they were satisfied with the prostheses and the service provided. This may be due to ongoing adaptation to the new device. The single child re-evaluated at 12 months showed improvement in prosthesis use, highlighting the potential benefits of early intervention coupled with motor re-education. Further research is needed to optimize prosthetic features and address initial challenges associated with prosthesis use. Full article
11 pages, 552 KiB  
Article
Acute Dosing Strategy with Vistula Tart Cherries for Recovery of Strenuous Exercise—A Feasibility Study
by Emma Squires, Ian H. Walshe, Alex Dodd, Edward Broadbelt, Oliver Hayman, Malachy P. McHugh and Glyn Howatson
Nutrients 2024, 16(16), 2709; https://doi.org/10.3390/nu16162709 - 15 Aug 2024
Viewed by 598
Abstract
Tart cherry (TC) consumption has become a popular nutritional strategy for recovery, particularly for the attenuation of markers associated with muscle damage. However, there are relatively few studies that have examined an acute dosing strategy. The aim of this pilot study was to [...] Read more.
Tart cherry (TC) consumption has become a popular nutritional strategy for recovery, particularly for the attenuation of markers associated with muscle damage. However, there are relatively few studies that have examined an acute dosing strategy. The aim of this pilot study was to explore the feasibility of using powdered Vistula TC for recovery following a bout of muscle-damaging exercise. Twenty-two recreationally active participants (mean ± SD age, stature, and mass were 23 ± 3 years old, 173 ± 10 cm, and 74 ± 17 kg, respectively) performed 40 (5 sets of 8 repetitions) maximal lengthening contractions of the elbow flexors. The participants were randomised to receive either a spray-dried TC extract or a calorie-matched placebo (12 TC, 10 placebo) for 4 days in total, starting on the day of exercise. Dependent measures of maximal voluntary contraction (MVC), muscle soreness (assessed via visual analogue scales; VAS), pain pressure threshold (PPT), range of motion (ROM), and upper arm limb girth were taken at baseline (pre), 24, 48, and 72 h post damaging exercise. There were significant changes over time among all the variables (MVC, VAS, PPT, ROM, and girth, p ≤ 0.014). There were no significant differences between the conditions for any of the variables (MVC, VAS, PPT, ROM, and girth, p > 0.3). The TC group did not recover at an accelerated rate compared to the placebo. This study provides initial insights into the use of powdered Vistula TC and its effect following strenuous (damaging) exercise bouts. Vistula TC did not improve recovery when taken acutely following a bout of damaging exercise to the elbow flexors. Full article
(This article belongs to the Special Issue Nutrition Interventions for Athletes' Performance)
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