Search Results (15,628)

Plants have evolved intricate signaling pathways, which operate as networks governed by feedback to deal with stressors. Nevertheless, the sophisticated molecular mechanisms underlying these routes still need to be comprehended, and experimental validation poses significant challenges and expenses. Consequently, computational hypothesis evaluation gains prominence in understanding plant signaling dynamics. Biosensors are genetically modified to emit light when exposed to a particular hormone, such as abscisic acid (ABA), enabling quantification. We developed computational models to simulate the relationship between ABA concentrations and bioluminescent sensors utilizing the Hill equation and ordinary differential equations (ODEs), aiding better hypothesis development regarding plant signaling. Based on simulation results, the luminescence intensity was recorded for a concentration of 47.646 RLUs for 1.5 μmol, given the specified parameters and model assumptions. This method enhances our understanding of plant signaling pathways at the cellular level, offering significant benefits to the scientific community in a cost-effective manner. The alignment of these computational predictions with experimental results emphasizes the robustness of our approach, providing a cost-effective means to validate mathematical models empirically. The research intended to correlate the bioluminescence of biosensors with plant signaling and its mathematical models for quantified detection of specific plant hormone ABA. Full article

Medical image classification, a pivotal task for diagnostic accuracy, poses unique challenges due to the intricate and variable nature of medical images compared to their natural counterparts. While Convolutional Neural Networks (CNNs) and Transformers are prevalent in this domain, each architecture has its drawbacks. CNNs, despite their strength in local feature extraction, fall short in capturing global context, whereas Transformers excel at global information but can overlook fine-grained details. The integration of CNNs and Transformers in a hybrid model aims to bridge this gap by enabling simultaneous local and global feature extraction. However, this approach remains constrained in its capacity to model long-range dependencies, thereby hindering the efficient extraction of distant features. To address these issues, we introduce the MambaConvT model, which employs a state-space approach. It begins by locally processing input features through multi-core convolution, enhancing the extraction of deep, discriminative local details. Next, depth-separable convolution with a 2D selective scanning module (SS2D) is employed to maintain a global receptive field and establish long-distance connections, capturing the fine-grained features. The model then combines hybrid features for comprehensive feature extraction, followed by global feature modeling to emphasize on global detail information and optimize feature representation. This paper conducts thorough performance experiments on different algorithms across four publicly available datasets and two private datasets. The results demonstrate that MambaConvT outperforms the latest classification algorithms in terms of accuracy, precision, recall, F1 score, and AUC value ratings, achieving superior performance in the precise classification of medical images. Full article

Accurately modeling the effects of illumination and shadows during head rotation is critical in computer vision for enhancing image realism and reducing artifacts. This study delves into the latent space of denoising diffusion models to identify compelling trajectories that can express continuous head rotation under varying lighting conditions. A key contribution of our work is the generation of additional labels from the CelebA dataset, categorizing images into three groups based on prevalent illumination direction: left, center, and right. These labels play a crucial role in our approach, enabling more precise manipulations and improved handling of lighting variations. Leveraging a recent embedding technique for Denoising Diffusion Implicit Models (DDIM), our method achieves noteworthy manipulations, encompassing a wide rotation angle of ±30°. while preserving individual distinct characteristics even under challenging illumination conditions. Our methodology involves computing trajectories that approximate clouds of latent representations of dataset samples with different yaw rotations through linear regression. Specific trajectories are obtained by analyzing subsets of data that share significant attributes with the source image, including light direction. Notably, our approach does not require any specific training of the generative model for the task of rotation; we merely compute and follow specific trajectories in the latent space of a pre-trained face generation model. This article showcases the potential of our approach and its current limitations through a qualitative discussion of notable examples. This study contributes to the ongoing advancements in representation learning and the semantic investigation of the latent space of generative models. Full article

The automotive industry is experiencing a significant shift, transitioning from traditional hardware-centric systems to more advanced software-defined architectures. This change is enabling enhanced autonomy, connectivity, safety, and improved in-vehicle experiences. Service-oriented architecture is crucial for achieving software-defined vehicles and creating new business opportunities for original equipment manufacturers. A software update approach that is rich in variability and based on a Merkle tree approach is proposed for new vehicle architecture requirements. Given the complexity of software updates in vehicles, particularly when dealing with multiple distributed electronic control units, this software-centric approach can be optimized to handle various architectures and configurations, ensuring consistency across all platforms. In this paper, our software update approach is expanded to cover the solution space of the feature-based product line engineering, and we show how to combine our approach with product line engineering in creative and unique ways to form a software-defined vehicle modular architecture. Then, we offer insights into the design of the Merkle trees utilized in our approach, emphasizing the relationship among the software modules, with a focus on their impact on software update performance. This approach streamlines the software update process and ensures that the safety as well as the security of the vehicle are continuously maintained. Full article

Studies of active region (AR) lifetimes are mostly restricted to short-lived ARs. The aim of this paper is to include recurrent ARs, which should be identified unambiguously. The first step is the algorithmic listing of possible returns; then, the candidates are visually checked using the unique HTML-feature of the Debrecen sunspot database. The final step is application of an asymmetric Gaussian function, introduced in previous articles, for short-lived ARs. This function has a surprisingly good fit to the data on correctly identified recurrent sunspot groups over several rotations enabling the reconstruction of the development on the far side of the sun. The Gnevyshev–Waldmeier rule for the area–lifetime relationship is not applicable for recurrent ARs; however, as a novel approach, a linear regression analysis extended to long lifetimes made it possible to recognize two populations of sizes for which two different area–lifetime relationships can be obtained. The lifetimes exhibit weak dependencies on the heliographic latitude and solar cycle phase. If an asymmetric Gaussian cannot be fit to the data, then they presumably belong to consecutive members of an active nest. Full article

In this paper, a meticulous modeling approach is proposed not only for a fuel cell stack itself but also for all auxiliary components that collectively form the fuel cell system. This comprehensive modeling approach encompasses a wide range of components, including, but not limited to, the hydrogen recirculation pump and the air compressor. Each component is thoroughly analyzed and modeled based on the detailed specifications provided by suppliers. This involves considering factors such as efficiency, operating parameters, response times, and interactions with other system elements. By integrating these detailed models, a holistic understanding of the entire fuel cell system’s performance can be attained. Such an approach enables engineers and designers to simulate various operating scenarios, predict system behavior under different conditions, and optimize the system design for maximum efficiency and reliability. Moreover, it allows for informed decision-making throughout the system’s development, deployment, and operational phases, ultimately leading to more robust and effective energy systems. The model validation is performed by comparing experimental data to theoretical results, and the observed difference does not exceed 3%. Full article

Swallowing is a complex neuromuscular activity regulated by the autonomic central nervous system, and impairment can lead to dysphagia, which is difficulty in swallowing. This research presents a novel approach that utilizes wireless, wearable technology for the continuous mechano-acoustic tracking of respiratory activities and swallowing. To address the challenge of accurately tracking swallowing amidst potential confounding activities or significant body movements, we employ two accelerometers. These accelerometers help distinguish between genuine swallowing events and other activities. By monitoring movements and vibrations through the skin surface, the developed device enables non-intrusive monitoring of swallowing dynamics and respiratory patterns. Our focus is on the development of both the wireless skin-interfaced device and an advanced algorithm capable of detecting swallowing dynamics in conjunction with respiratory phases. The device and algorithm demonstrate robustness in detecting respiratory patterns and swallowing instances, even in scenarios where users exhibit periodic movements due to disease or daily activities. Furthermore, peak detection using an adaptive threshold automatically adjusts to an individual’s signal strength, facilitating the detection of swallowing signals without the need for individual adjustments. This innovation has significant potential for enhancing patient training and rehabilitation programs aimed at addressing dysphagia and related respiratory issues. Full article

Multi-access edge computing (MEC) has attracted the interest of the research and industrial community to support Internet of things (IoT) applications by enabling efficient data processing and minimizing latency. This paper presents significant contributions toward optimizing the resource allocation and enhancing the decision-making process in edge computing environments. Specifically, the TRUST-ME model is introduced, which consists of multiple edge servers and IoT devices, i.e., users, with varied computing tasks offloaded to the MEC servers. A utility function was designed to quantify the benefits in terms of latency and cost for the IoT device while utilizing the MEC servers’ computing capacities. The core innovation of our work is a novel trust model that was designed to evaluate the IoT devices’ confidence in MEC servers. This model integrates both direct and indirect trust and reflects the trustworthiness of the servers based on the direct interactions and social feedback from other devices using the same servers. This dual trust approach helps with accurately gauging the reliability of MEC services and ensuring more informed decision making. A reinforcement learning framework based on the optimistic Q-learning with an upper confidence bounds action selection algorithm enables the IoT devices to autonomously select a MEC server to process their computing tasks. Also, a multilateral bargaining model is proposed for fair resource allocation of the MEC servers’ computing resources to the users while accounting for their computing demands. Numerical simulations demonstrated the operational effectiveness, convergence, and scalability of the TRUST-ME model, which was validated through real-world scenarios and comprehensive comparative evaluations against existing approaches. Full article

Forest site productivity estimates are crucial for making informed forest resource management decisions. These estimates are valuable both for the tree species currently growing in the stands and for those being considered for future stands. Current models are generally designed for pure stands and do not account for the influence of climate on tree growth. Consequently, site index (SI) conversion equations were developed specifically for jack pine (Pinus banksiana Lamb.) and trembling aspen (Populus tremuloides Michx.) trees grown in naturally originated mixed stands. This work involved sampling 186 trees (93 of each species) from 31 even-aged mixed stands (3 trees per species per site) across Ontario, Canada. Stem analysis data from these trees were utilized to develop stand height growth models by incorporating climate variables for each species. The models were developed using a mixed effects modelling approach. The SI of one species was correlated with that of the other species and climate variables to establish SI conversion equations. The effect of climate on site productivity was evaluated by projecting stand heights at four geographic locations (east, center, west, and far west) in Ontario from 2022 to 2100 using the derived stand height growth models. Height projections were made under three emissions scenarios reflecting varying levels of radiative forcing by the end of the century (2.6, 4.5, and 8.5 watts m⁻²). Climate effects were observed to vary across different regions, with the least and most pronounced effects noted in the central and far western areas, respectively, for jack pine, while effects were relatively similar across all locations for trembling aspen. Stand heights and SIs of jack pine and trembling aspen trees grown in naturally originated mixed stands can be estimated using the height growth models developed here. Similarly, SI conversion equations enable the estimation of the SI for one species based on the SI of another species and environmental variables. Full article

The proliferation of wearable technology enables the generation of vast amounts of sensor data, offering significant opportunities for advancements in health monitoring, activity recognition, and personalized medicine. However, the complexity and volume of these data present substantial challenges in data modeling and analysis, which have been addressed with approaches spanning time series modeling to deep learning techniques. The latest frontier in this domain is the adoption of large language models (LLMs), such as GPT-4 and Llama, for data analysis, modeling, understanding, and human behavior monitoring through the lens of wearable sensor data. This survey explores the current trends and challenges in applying LLMs for sensor-based human activity recognition and behavior modeling. We discuss the nature of wearable sensor data, the capabilities and limitations of LLMs in modeling them, and their integration with traditional machine learning techniques. We also identify key challenges, including data quality, computational requirements, interpretability, and privacy concerns. By examining case studies and successful applications, we highlight the potential of LLMs in enhancing the analysis and interpretation of wearable sensor data. Finally, we propose future directions for research, emphasizing the need for improved preprocessing techniques, more efficient and scalable models, and interdisciplinary collaboration. This survey aims to provide a comprehensive overview of the intersection between wearable sensor data and LLMs, offering insights into the current state and future prospects of this emerging field. Full article

Reduced-order models (ROMs) have achieved a lot of success in reducing the computational cost of traditional numerical methods across many disciplines. In fluid dynamics, ROMs have been successful in providing efficient and relatively accurate solutions for the numerical simulation of laminar flows. For convection-dominated (e.g., turbulent) flows, however, standard ROMs generally yield inaccurate results, usually affected by spurious oscillations. Thus, ROMs are usually equipped with numerical stabilization or closure models in order to account for the effect of the discarded modes. The literature on ROM closures and stabilizations is large and growing fast. In this paper, instead of reviewing all the ROM closures and stabilizations, we took a more modest step and focused on one particular type of ROM closure and stabilization that is inspired by large eddy simulation (LES), a classical strategy in computational fluid dynamics (CFD). These ROMs, which we call LES-ROMs, are extremely easy to implement, very efficient, and accurate. Indeed, LES-ROMs are modular and generally require minimal modifications to standard (“legacy”) ROM formulations. Furthermore, the computational overhead of these modifications is minimal. Finally, carefully tuned LES-ROMs can accurately capture the average physical quantities of interest in challenging convection-dominated flows in science and engineering applications. LES-ROMs are constructed by leveraging spatial filtering, which is the same principle used to build classical LES models. This ensures a modeling consistency between LES-ROMs and the approaches that generated the data used to train them. It also “bridges” two distinct research fields (LES and ROMs) that have been disconnected until now. This paper is a review of LES-ROMs, with a particular focus on the LES concepts and models that enable the construction of LES-inspired ROMs and the bridging of LES and reduced-order modeling. This paper starts with a description of a versatile LES strategy called evolve–filter–relax (EFR) that has been successfully used as a full-order method for both incompressible and compressible convection-dominated flows. We present evidence of this success. We then show how the EFR strategy, and spatial filtering in general, can be leveraged to construct LES-ROMs (e.g., EFR-ROM). Several applications of LES-ROMs to the numerical simulation of incompressible and compressible convection-dominated flows are presented. Finally, we draw conclusions and outline several research directions and open questions in LES-ROM development. While we do not claim this review to be comprehensive, we certainly hope it serves as a brief and friendly introduction to this exciting research area, which we believe has a lot of potential in the practical numerical simulation of convection-dominated flows in science, engineering, and medicine. Full article

Foods contaminants pose a challenge for food producers and consumers. Due to its spontaneous formation during heating and storage, hydroxymethylfurfural (HMF) is a prevalent contaminant in foods rich in carbohydrates and proteins. Colorimetric assays, such as the Seliwanoff test, offer a rapid and cost-effective method for HMF quantification but require careful optimization to ensure accuracy. We addressed potential interference in the Seliwanoff assay by systematically evaluating parameters like incubation time, temperature, and resorcinol or hydrochloric acid concentration, as well as the presence of interfering carbohydrates. Samples were analyzed using a UV–Vis spectrophotometer in scan mode, and data obtained were validated using HPLC, which also enabled quantification of unreacted HMF for assessing the protocol’s accuracy. Incubation time and hydrochloric acid percentage positively influenced the colorimetric assay, while the opposite effect was observed with the increase in resorcinol concentration. Interference from carbohydrates was eliminated by reducing the acid content in the working reagent. HPLC analyses corroborated the spectrophotometer data and confirmed the efficacy of the proposed method. The average HMF content in balsamic vinegar samples was 1.97 ± 0.94 mg/mL. Spectrophotometric approaches demonstrated to efficiently determine HMF in complex food matrices. The HMF levels detected in balsamic vinegars significantly exceeded the maximum limits established for honey. This finding underscores the urgent need for regulations that restrict contaminant levels in various food products. Full article

Due to the lack of sufficient valid labeled data and severe channel fading, the recognition of various underwater acoustic (UWA) communication modulation types still faces significant challenges. In this paper, we propose a lightweight UWA communication type recognition network based on semi-supervised learning, named the SSL-LRN. In the SSL-LRN, a mean teacher–student mechanism is developed to improve learning performance by averaging the weights of multiple models, thereby improving recognition accuracy for insufficiently labeled data. The SSL-LRN employs techniques such as quantization and small convolutional kernels to reduce floating-point operations (FLOPs), enabling its deployment on underwater mobile nodes. To mitigate the performance loss caused by quantization, the SSL-LRN adopts a channel expansion module to optimize the neuron distribution. It also employs an attention mechanism to enhance the recognition robustness for frequency-selective-fading channels. Pool and lake experiments demonstrate that the framework effectively recognizes most modulation types, achieving a more than 5% increase in recognition accuracy at a 0 dB signal-to-noise ratio (SNRs) while reducing FLOPs by 84.9% compared with baseline algorithms. Even with only 10% labeled data, the performance of the SSL-LRN approaches that of the fully supervised LRN algorithm. Full article

Food safety control is a key issue in the food and agriculture industries. For such purposes, developing miniaturized analytical methods is critical for enabling the rapid and sensitive detection of food supplements, allergens, and pollutants. Here, a novel bioanalytical methodology based on DNA-functionalized gold nanoparticles (AuNPs) and colorimetric detection was developed to detect the presence of sesame (a major allergen) through sesame seed DNA as a target, in food samples. The presence of sesame DNA induces controlled nanoparticle aggregation/desegregation, resulting in a color change (from blue to red) proportional to sesame DNA concentration. The incorporation of multicomponent nucleic acid enzymes (MNAzymes) in this strategy has been carried out to perform an isothermal signal amplification strategy to improve the sensitivity of detection. Also, open-source software for color analysis was used to ensure an unbiased visual color-change detection, enhancing detection accuracy and sensitivity and opening the possibility of performing a simple and decentralized analyte detection. The method successfully detected the presence of sesame DNA in sesame seed, sesame oil, olive oil, and sunflower oil. In brief, the developed approach constitutes a simple and affordable alternative to perform a highly sensitive detection of DNA in food without complex methodologies or the requirement of expensive instrumentation. Full article

High-resolution and thermal infrared hyperspectral data acquired from the Thermal Infrared Airborne Spectrographic Imager (TASI) have been recognized as efficient tools in geology, demonstrating significant potential for rock discernment. Deep learning (DL), as an advanced technology, has driven substantial advancements in lithological mapping by automatically extracting high-level semantic features from images to enhance recognition accuracy. However, gathering sufficient high-quality lithological samples for model training is challenging in many scenarios, posing limitations for data-driven DL approaches. Moreover, existing sample collection approaches are plagued by limited verifiability, subjective bias, and variation in the spectra of the same class at different locations. To tackle these challenges, a novel sample generation method called multi-lithology spectra sample selection (MLS3) is first employed. This method involves multiple steps: multiple spectra extraction, spectra combination and optimization, lithological type identification, and sample selection. In this study, the TASI hyperspectral data collected from the Liuyuan area in Gansu Province, China, were used as experimental data. Samples generated based on MLS3 were fed into five typical DL models, including two-dimensional convolutional neural network (2D-CNN), hybrid spectral CNN (HybridSN), multiscale residual network (MSRN), spectral-spatial residual network (SSRN), and spectral partitioning residual network (SPRN) for lithological mapping. Among these models, the accuracy of the SPRN reaches 84.03%, outperforming the other algorithms. Furthermore, MLS3 demonstrates superior performance, achieving an overall accuracy of 2.25–6.96% higher than other sample collection methods when SPRN is used as the DL framework. In general, MLS3 enables both the quantity and quality of samples, providing inspiration for the application of DL to hyperspectral lithological mapping. Full article