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15 pages, 3997 KiB  
Article
A Generalized Load Model Considering the Fault Ride-Through Capability of Distributed PV Generation System
by Haiyun Wang, Qian Chen, Linyu Zhang, Xiyu Yin, Han Cui, Zhijian Zhang, Huayue Wei and Xiaoyue Chen
Energies 2024, 17(14), 3595; https://doi.org/10.3390/en17143595 (registering DOI) - 22 Jul 2024
Abstract
Considering the voltage stability problem brought by large-scale distributed PV access to the distribution network, this paper proposes a generalized load model that considers the fault ride-through capability of distributed PV. Firstly, the detailed model of the distribution network is established, and the [...] Read more.
Considering the voltage stability problem brought by large-scale distributed PV access to the distribution network, this paper proposes a generalized load model that considers the fault ride-through capability of distributed PV. Firstly, the detailed model of the distribution network is established, and the detailed model is calibrated based on the measured data, the simulation errors are below 1%. And then establish a generalized load model considering distributed PV high and low voltage traversal ability. The sensitivity analysis results are used to rank the parameters to be identified, and the parameters with higher sensitivity are identified. The parameters are obtained from the detailed model and measured data, and four sets of parameters are identified and simulated under different PV penetration rates and fault conditions. The calculated fitting errors are less than 1%. The results show that the generalized load gray box model of the distribution network with distributed PV high and low voltage ride-through capability can reflect the dynamic characteristics of the distribution network well. Full article
(This article belongs to the Section A2: Solar Energy and Photovoltaic Systems)
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13 pages, 448 KiB  
Article
Beverage Consumption Patterns and Their Association with Metabolic Health in Adults from Families at High Risk for Type 2 Diabetes in Europe—The Feel4Diabetes Study
by Paris Kantaras, Niki Mourouti, Theodora Mouratidou, Ekaterini Chatzaki, Makrina Karaglani, Violeta Iotova, Natalya Usheva, Imre Rurik, Péter Torzsa, Luis A. Moreno, Stavros Liatis, Konstantinos Makrilakis and Yannis Manios
Endocrines 2024, 5(3), 277-289; https://doi.org/10.3390/endocrines5030020 (registering DOI) - 22 Jul 2024
Abstract
In total, 3274 adults (65.2% females) from six European countries were included in this cross-sectional analysis using data from the baseline assessment of the Feel4Diabetes study. Anthropometric, sociodemographic, dietary and behavioral data were assessed, and the existence of metabolic syndrome (MetS) was recorded. [...] Read more.
In total, 3274 adults (65.2% females) from six European countries were included in this cross-sectional analysis using data from the baseline assessment of the Feel4Diabetes study. Anthropometric, sociodemographic, dietary and behavioral data were assessed, and the existence of metabolic syndrome (MetS) was recorded. Beverage consumption patterns (BCPs) were derived via principal component analysis. Three BCPs were derived explaining 39.5% of the total variation. BCP1 was labeled as “Alcoholic beverage pattern”, which loaded heavily on high consumption of beer/cider, wine and other spirits; BCP2 was labeled as “High in sugars beverage pattern” that was mainly characterized by high consumption of soft drinks with sugar, juice containing sugar and low consumption of water; and BCP3 was labeled as “Healthy beverage pattern” that was mainly characterized by high consumption of water, tea, fruit juice freshly squeezed or prepacked without sugar and low consumption of soft drinks without sugar. After adjusting for various confounders, BCP2 was positively associated with elevated triglycerides (p = 0.001), elevated blood pressure (p = 0.001) elevated fasting glucose (p = 0.008) and the existence of MetS (p = 0.006), while BCP1 was inversely associated with reduced HDL-C (p = 0.005) and BCP3 was inversely associated with elevated blood pressure (p = 0.047). The establishment of policy actions as well as public health nutritional education can contribute to the promotion of a healthy beverage consumption. Full article
(This article belongs to the Special Issue Advances in Diabetes Care)
31 pages, 13226 KiB  
Article
Extended Comparison and Performance Analysis for Mobile Ad-Hoc Networks Routing Protocols Based on Different Traffic Load Patterns and Performance Metrics
by Qutaiba Razouqi, Ahmed Boushehri, Mohamed Gaballa, Lina Alsaleh and Maysam Abbod
Electronics 2024, 13(14), 2877; https://doi.org/10.3390/electronics13142877 (registering DOI) - 22 Jul 2024
Abstract
A mobile ad-hoc network (MANET) is a network of mobile nodes that dynamically form a transitory network lacking any existence of infrastructure and any form of centralized management. Nodes in ad hoc networks are powered by batteries with a limited lifespan and communicate [...] Read more.
A mobile ad-hoc network (MANET) is a network of mobile nodes that dynamically form a transitory network lacking any existence of infrastructure and any form of centralized management. Nodes in ad hoc networks are powered by batteries with a limited lifespan and communicate in a restricted bandwidth. The unpredictable environment of a MANET may run into a major concern in the routing mechanism, therefore the need for a routing protocol with robust performance is still one of the key challenges in MANET deployment. In this work, a comparative comparison and extensive simulation analysis have been carried out for three major routing protocols: destination sequenced distance vector (DSDV), dynamic source routing (DSR) and ad hoc on-demand distance vector (AODV). Protocol evaluation has been extended by considering several simulation arrangements, different classes of traffic load patterns and diverse performance metrics. Based on packet rate change, node quantity and node speed, simulation scenarios were generated. Protocols were investigated against energy consumption, throughput, lost packets, routing load and packet delivery fraction for three types of traffic load patterns regular, irregular and joint traffic. DSR and AODV protocols proved to be more reliable when joint traffic was implemented when node speed and packets variations are considered. DSDV protocol verifies outstanding response over other protocols in terms of energy consumption when either regular or irregular traffic is applied. The simulation results for DSR protocol have verified the superiority over other protocols in 9 simulation scenarios when diverse metrics are considered. DSDV showed optimal performance in 7 cases, especially at low packet rates and in networks with minimum number of nodes. Similarly, AODV protocol showed outstanding performance in 6 scenarios, when higher packet rates and node mobility are considered. Full article
(This article belongs to the Special Issue New Insight into Network Virtualization and Management)
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25 pages, 6434 KiB  
Article
Assessment of the Local Impact of Retention Reservoirs—A Case Study of Jagodno (Existing) and Sarny (Planned) Reservoirs Located in Poland
by Maksymilian Połomski and Mirosław Wiatkowski
Water 2024, 16(14), 2061; https://doi.org/10.3390/w16142061 (registering DOI) - 22 Jul 2024
Abstract
The construction of retention reservoirs that cause permanent water damming is a complex subject and requires an interdisciplinary approach to environmental issues. The scope of the conducted study includes (1) a natural inventory of the area of Jagodno Reservoir in central Poland, which [...] Read more.
The construction of retention reservoirs that cause permanent water damming is a complex subject and requires an interdisciplinary approach to environmental issues. The scope of the conducted study includes (1) a natural inventory of the area of Jagodno Reservoir in central Poland, which has been in operation for almost a decade, (2) a natural inventory of the area where a reservoir of similar size could potentially be built (Sarny, in southwestern Poland), (3) an assessment of the local community’s attitudes toward the operation or construction of individual facilities, (4) analysis and use of the obtained results to predict the local impact of Sarny Reservoir. The results of this study indicate areas where the impact of Jagodno Reservoir should be considered negative, neutral, or positive and what effect can be expected during the construction of Sarny Reservoir. One of the more significant results for Jagodno Reservoir, we should point out, is the appearance of a few waterfowl breeding at the site (4 species), a substantial expansion of the ichthyofauna population (from 9 to 24 species, which does not apply only to native species), a local loss of 91E0 habitat (willow riparian forests) and the appearance of one species of an invasive plant (Canadian goldenrod), a favorable impact on the water quality of the River Wiązownica (reduction in total and nitrate nitrogen loads by an average of 43.4% and 58.2%, respectively), and a positive assessment of the reservoir’s impact on the development of the region by the local community (19 out of 26 village leaders expressed positive opinions with no unambiguously negative votes). Full article
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23 pages, 9408 KiB  
Article
Evolution of Industrial Robots from the Perspective of the Metaverse: Integration of Virtual and Physical Realities and Human–Robot Collaboration
by Jing You, Zhiyuan Wu, Wei Wei, Ning Li and Yuhua Yang
Appl. Sci. 2024, 14(14), 6369; https://doi.org/10.3390/app14146369 (registering DOI) - 22 Jul 2024
Abstract
During the transition from Industry 4.0 to Industry 5.0, industrial robotics technology faces the need for intelligent and highly integrated development. Metaverse technology creates immersive and interactive virtual environments, allowing technicians to perform simulations and experiments in the virtual world, and overcoming the [...] Read more.
During the transition from Industry 4.0 to Industry 5.0, industrial robotics technology faces the need for intelligent and highly integrated development. Metaverse technology creates immersive and interactive virtual environments, allowing technicians to perform simulations and experiments in the virtual world, and overcoming the limitations of traditional industrial operations. This paper explores the application and evolution of metaverse technology in the field of industrial robotics, focusing on the realization of virtual–real integration and human–machine collaboration. It proposes a design framework for a virtual–real interaction system based on the ROS and WEB technologies, supporting robot connectivity, posture display, coordinate axis conversion, and cross-platform multi-robot loading. This paper emphasizes the study of two key technologies for the system: virtual–real model communication and virtual–real model transformation. A general communication mechanism is designed and implemented based on the ROS, using the ROS topic subscription to achieve connection and real-time data communication between physical robots and virtual models, and utilizing URDF model transformation technology for model invocation and display. Compared with traditional simulation software, i.e., KUKA Sim PRO (version 1.1) and RobotStudio (version 6.08), the system improves model loading by 45.58% and 24.72%, and the drive response by 41.50% and 28.75%. This system not only supports virtual simulation and training but also enables the operation of physical industrial robots, provides persistent data storage, and supports action reproduction and offline data analysis and decision making. Full article
(This article belongs to the Topic Smart Production in Terms of Industry 4.0 and 5.0)
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14 pages, 4408 KiB  
Article
Comparative Study on Mechanical Response in Rigid Pavement Structures of Static and Dynamic Finite Element Models
by Qiao Meng, Ke Zhong, Yuchun Li and Mingzhi Sun
Aerospace 2024, 11(7), 596; https://doi.org/10.3390/aerospace11070596 (registering DOI) - 22 Jul 2024
Abstract
The safety of airport runways is important to guarantee aircraft taking-off, landing, and taxiing, and the comparison of the mechanical response of pavement structures under dynamic and static loading by LS-DYNA has rarely been studied. The purpose of this work is to separate [...] Read more.
The safety of airport runways is important to guarantee aircraft taking-off, landing, and taxiing, and the comparison of the mechanical response of pavement structures under dynamic and static loading by LS-DYNA has rarely been studied. The purpose of this work is to separate two analysis methods to investigate the mechanical response of rigid airport pavements. Firstly, a tire–road coupling model of an airfield was established to evaluate the suitability of dynamic and static analyses. Then, the effects of landing pitch angles, sinking speeds, and tire pressures on the effective stress, effective strain, and z-displacement of the runway were investigated for both dynamic and static analysis. Finally, the significance of influence factors was analyzed by regression analysis in Statistical Product and Service Solutions (SPSS). The results indicated that the effective stress, effective strain, and z-displacement of the runway increased with a decrease in the landing pitch angle, which also increased with an increase in the sinking speed and tire pressure. It was demonstrated that the difference in pavement mechanical response between dynamic and static analyses progressively widened at high tire pressure and sinking speed. In other words, the static analysis method can be adopted to assess the dynamic mechanical behavior when the landing pitch angle is large and the tire pressure is small. Among the various factors of mechanical response, the effect of tire pressure was the most obvious, followed by sinking speed and landing pitch angle. The work proposes a new approach to understanding the mechanical behavior of runways under complicated and varied conditions, evaluates the applicability of the dynamic and static mechanical analysis methods, identifies key factors in the dynamic and static mechanical analysis of rigid runways, and provides technical support for improving and maintaining the impact resistance of pavement facilities. Full article
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15 pages, 7305 KiB  
Article
Improving Mud Brick Durability in Ancient Closed-Box Tombs: A Graphene Oxide Nanoparticle Approach
by Ahmed Sallam, Ghazy Abdullah Albaqawy, Mabrouk Touahmia, Mustapha Boukendakdji and Mona M. E. Khalil
Buildings 2024, 14(7), 2248; https://doi.org/10.3390/buildings14072248 (registering DOI) - 22 Jul 2024
Abstract
This paper presents a novel concept for significantly enhancing the strength and durability of ancient closed-box tombs. These tombs hold significant philosophical values, and their architecture serves as a valuable data source, providing insights into the cultural stage of the society in which [...] Read more.
This paper presents a novel concept for significantly enhancing the strength and durability of ancient closed-box tombs. These tombs hold significant philosophical values, and their architecture serves as a valuable data source, providing insights into the cultural stage of the society in which it was constructed. Throughout medieval and modern times, clay bricks remained a prevalent material for tomb construction due to their affordability and design flexibility. However, these structures currently face neglect and weakening, requiring imperative intervention of protection to prevent them from potential deterioration or extinction. The key objective of this research is to explore the potential use of graphene oxide (GO), a novel nanomaterial, as a treatment method to enhance the durability of mud brick tombs in Aswan, Egypt. Samples of mud bricks were examined and characterized using various techniques, including SEM-EDX, TEM, PLM, XRF, XRD, and mechanical properties analysis. The results indicated that GO nanomaterials significantly improve the mechanical properties of mud brick tombs, allowing them to resist more compressive loading and ultimately resulting in more durable and long-lasting structures. By using these innovative materials, effective restoration and preservation of these ancient structures for future generations could be viable. This research has the potential to revolutionize the preservation of closed-box tombs, ensuring these historical landmarks stand longer the test of time. Full article
(This article belongs to the Special Issue Advanced Research on Cultural Heritage)
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19 pages, 18904 KiB  
Article
Seismic Response and Collapse Analysis of a Transmission Tower Structure: Assessing the Impact of the Damage Accumulation Effect
by Pingping Nie, Haiqing Liu, Yunlong Wang and Siyu Han
Buildings 2024, 14(7), 2243; https://doi.org/10.3390/buildings14072243 (registering DOI) - 21 Jul 2024
Abstract
This paper delves into the impact of the damage accumulation effect, which leads to the degradation of material strength and stiffness, on the seismic resistance of transmission towers. Building upon the elastic–plastic finite element theory, a mixed hardening constitutive model is derived for [...] Read more.
This paper delves into the impact of the damage accumulation effect, which leads to the degradation of material strength and stiffness, on the seismic resistance of transmission towers. Building upon the elastic–plastic finite element theory, a mixed hardening constitutive model is derived for circular steel tubes, standard elements in transmission towers, incorporating the damage accumulation effect. A user material subroutine, UMAT, is created within the LS–DYNA framework. The program’s validity and reliability are established through axial constant–amplitude loading tests on single steel tubes. The subroutine is employed to conduct the incremental dynamic analysis (IDA) of an individual transmission tower and to contrast it with the structure utilizing the Plastic Kinematic material model, assessing the discrepancies in tower top displacements and segment damage indices (SDIs) at both macroscopic and microscopic scales. The results shows that the Plastic Kinematic model inflates the seismic performance of the transmission tower. When considering the damage accumulation effect in structural failure, the damage index of the members increases, leading to a reduction in both the structural strength and stiffness. The dynamic response in the plastic phase becomes more pronounced, and the onset of structural failure is accelerated. Consequently, structural analysis under seismic conditions should account for the damage accumulation process. Through the delineation of member and segment damage, the extent of damage to transmission tower segments can be quantitatively assessed. Subsequently, the ultimate load–bearing capacity and the most vulnerable location of the transmission tower can be ascertained. Finally, this paper provides a detailed analysis of the transmission tower collapse process under seismic action and summarizes the mechanism of collapse for the structure. Full article
(This article belongs to the Special Issue Seismic Performance and Durability of Engineering Structures)
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24 pages, 2469 KiB  
Article
Optimized Discrete Nonlinear Control of Alternating Current Three-Phase Motors via an Industrial Variable Frequency Drive
by Nicolás Cervantes-Escorcia, Omar-Jacobo Santos-Sánchez, Liliam Rodríguez-Guerrero, Hugo Romero-Trejo and Orlando García-Pérez
Appl. Sci. 2024, 14(14), 6355; https://doi.org/10.3390/app14146355 (registering DOI) - 21 Jul 2024
Abstract
This article presents a suboptimal nonlinear control strategy to improve the dynamics of a three-phase alternating current (AC) motor. Using dynamic programming, the calculation of the Bellman function is avoided by determining a suboptimal control sequence that locally minimizes a quadratic performance index [...] Read more.
This article presents a suboptimal nonlinear control strategy to improve the dynamics of a three-phase alternating current (AC) motor. Using dynamic programming, the calculation of the Bellman function is avoided by determining a suboptimal control sequence that locally minimizes a quadratic performance index at each step. The motor’s fixed-frame nonlinear mathematical model controls the stator currents, rotor magnetic fluxes, and rotor angular speed by applying voltages to the stator. Experimental tests are conducted using a Delta VFD007EL11A variable frequency drive (VFD), demonstrating improved motor state behavior and performance compared to an optimal proportional integral (PI) control and a fixed reference input in the VFD. The experiments include set point changes and a comparative analysis of the energy consumption between both controllers considering two cases: free and with load on the motor shaft. Full article
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20 pages, 3323 KiB  
Article
Slope Stability Analysis of Rockfill Embankments Considering Stress-Dependent Spatial Variability in Friction Angle of Granular Materials
by Congyong Ran, Zhengjun Zhou, Xiang Lu, Binfeng Gong, Yuanyuan Jiang and Zhenyu Wu
Appl. Sci. 2024, 14(14), 6354; https://doi.org/10.3390/app14146354 (registering DOI) - 21 Jul 2024
Abstract
Slope stability is a major safety concern of rockfill embankments. Since rockfills are incohesive materials, only friction angle is considered as a shear strength parameter in the slope stability analysis of rockfill embankments. Recently, it was found that confining pressure can significantly affect [...] Read more.
Slope stability is a major safety concern of rockfill embankments. Since rockfills are incohesive materials, only friction angle is considered as a shear strength parameter in the slope stability analysis of rockfill embankments. Recently, it was found that confining pressure can significantly affect the mean value and variance of the friction angle of rockfills. Since the confining pressure spatially varies within a rockfill embankment, the effect of stress-dependent spatial variability in the friction angle of rockfills should be investigated for slope stability evaluation of rockfill embankments. In the framework of the Limit Equilibrium Method (LEM), an approach is proposed for the slope stability analysis of rockfill embankments considering the stress-dependent spatial variability in the friction angle. The safety factors of slope stability are computed with variable values of the friction angle at the bases of slices which are determined by the stress-dependent mean value and variance of the friction angle of rockfills. The slope stability of a homogeneous rockfill embankment is analyzed to illustrate the proposed approach, and a parametric analysis is carried out to explore the effect of variation in the parameters of the variance function of friction angle on slope stability. The illustrative example demonstrates that the stress-dependent spatial variability of friction angle along the slip surface is obvious and is affected by the location of the slip surface and the loading condition. The effects of the stress-dependent spatial variability of the friction angle on the slope stability of high rockfill embankments should be considered. Full article
(This article belongs to the Special Issue Slope Stability and Earth Retaining Structures—2nd Edition)
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13 pages, 6840 KiB  
Article
Development of Bivalent Aptamer-DNA Carrier-Doxorubicin Conjugates for Targeted Killing of Esophageal Squamous Cell Carcinoma Cells
by Tianlu Zhang, Kai Yin, Xidong Niu, Xue Bai, Zhaoting Wang, Mengmeng Ji and Baoyin Yuan
Int. J. Mol. Sci. 2024, 25(14), 7959; https://doi.org/10.3390/ijms25147959 (registering DOI) - 21 Jul 2024
Abstract
Esophageal cancer ranks the seventh in cancer incidence and the sixth in cancer death. Esophageal squamous cell carcinoma (ESCC) accounts for approximately 90% of the total cases of esophageal cancer. Chemotherapy is the most effective drug-based method for treatment of esophageal cancer. However, [...] Read more.
Esophageal cancer ranks the seventh in cancer incidence and the sixth in cancer death. Esophageal squamous cell carcinoma (ESCC) accounts for approximately 90% of the total cases of esophageal cancer. Chemotherapy is the most effective drug-based method for treatment of esophageal cancer. However, severe side effects of traditional chemotherapy limit its treatment efficacy. Targeted chemotherapy can deliver chemotherapeutic drugs to cancer cells and specifically kill these cells with reduced side effects. In the work, the bivalent aptamer-DNA carrier (BAD) was designed by using an ESCC cell-specific aptamer as the recognition molecule and a GC base-rich DNA sequence as the drug carrier. With doxorubicin (Dox) as chemotherapeutic drugs, the bivalent aptamer-DNA-Dox conjugate (BADD) was constructed for targeted killing of ESCC cells. Firstly, the truncated A2(35) aptamer with a retained binding ability was obtained through optimization of an intact A2(80) aptamer and was used to fuse with DNA carrier sequences for constructing the BAD through simple DNA hybridization. The results of gel electrophoresis and flow cytometry analysis showed that the BAD was successfully constructed and had a stronger binding affinity than monovalent A2(35). Then, the BAD was loaded with Dox drugs to construct the BADD through noncovalent intercalation. The results of fluorescence spectra and flow cytometry assays showed that the BADD was successfully constructed and can bind to target cells strongly. Confocal imaging further displayed that the BADD can be specifically internalized into target cells and release Dox. The results of CCK-8 assays, Calcein AM/PI staining, and wound healing assays demonstrated that the BADD can specifically kill target cells, but not control cells. Our results demonstrate that the developed BADD can specifically deliver doxorubicin to target ESCC cells and selectively kill these cells, offering a potentially effective strategy for targeted chemotherapy of ESCC. Full article
(This article belongs to the Special Issue Functional Molecules in Tracing and Cancer Therapeutics)
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15 pages, 6012 KiB  
Article
Numerical and Experimental Modal Analysis of a Gyroid Inconel 718 Structure for Stiffness Specification in the Design of Load-Bearing Components
by Katarina Monkova, Sanjin Braut, Peter Pavol Monka, Ante Skoblar and Martin Pollák
Materials 2024, 17(14), 3595; https://doi.org/10.3390/ma17143595 (registering DOI) - 21 Jul 2024
Abstract
The study aims to investigate the modal properties of a 60 × 70 × 80 mm gyroid structure made of Inconel 718 with 67.5% porosity. The geometry model for sample production was created using the software PTC Creo, whereas the geometry model for [...] Read more.
The study aims to investigate the modal properties of a 60 × 70 × 80 mm gyroid structure made of Inconel 718 with 67.5% porosity. The geometry model for sample production was created using the software PTC Creo, whereas the geometry model for numerical analysis was created using the Python application ScaffoldStructures. FE analysis was performed using ANSYS 2024 R1 software. Free boundary conditions were used in experimental modal analysis to ensure feasibility. The analysis identified the first four natural frequencies ranging from 10 to 16 kHz. The results revealed that the first natural frequency corresponds to the first torsional frequency about the Z axis, the second to the first flexural mode in the XZ plane, the third to the first bending mode in the YZ plane, and the fourth to the first torsional mode about the X axis. Small differences between the results of numerical and experimental modal analysis can be attributed to geometric errors in the manufactured sample, careless removal from the platform, and due to reduction in the complexity of the numerical FE model. Employing modal analysis of a component, the stiffness of a lightweight component can be revealed. In the case of the sample with the cellular structure of gyroid type, relatively high stiffness regarding the material savings was identified, which can be advantageously used in many applications. Full article
(This article belongs to the Special Issue Preparation and Application of Regularly Structured Porous Materials)
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18 pages, 2399 KiB  
Article
Microbiological and Salivary Biomarkers Successfully Predict Site-Specific and Whole-Mouth Outcomes of Nonsurgical Periodontal Treatment
by Ali JB Al-Sharqi and Ali Abdulkareem
J. Clin. Med. 2024, 13(14), 4256; https://doi.org/10.3390/jcm13144256 (registering DOI) - 21 Jul 2024
Abstract
Background/Objectives: Nonsurgical periodontal treatment (NSPT) is the gold-standard technique for treating periodontitis. However, an individual’s susceptibility or the inadequate removal of subgingival biofilms could lead to unfavorable responses to NSPT. This study aimed to assess the potential of salivary and microbiological biomarkers [...] Read more.
Background/Objectives: Nonsurgical periodontal treatment (NSPT) is the gold-standard technique for treating periodontitis. However, an individual’s susceptibility or the inadequate removal of subgingival biofilms could lead to unfavorable responses to NSPT. This study aimed to assess the potential of salivary and microbiological biomarkers in predicting the site-specific and whole-mouth outcomes of NSPT. Methods: A total of 68 periodontitis patients exhibiting 1111 periodontal pockets 4 to 6 mm in depth completed the active phase of periodontal treatment. Clinical periodontal parameters, saliva, and subgingival biofilm samples were collected from each patient at baseline and three months after NSPT. A quantitative PCR assay was used to detect the presence of Fusobaterium nucleatum and Porphyromonas gingivalis in the biofilm samples. Salivary biomarkers including matrix metalloproteinase (MMP)-9, glutathione S-transferase (GST), and Annexin-1 were assayed both qualitatively (Western blot analysis) and quantitively (ELISA). Results: NSPT yielded significant improvements in all clinical parameters, including a reduction in bacterial load and decreased levels of MMP-9 together with increased concentrations of GST and Annexin-1. The binary logistic regression suggested that the overall accuracy of P. gingivalis identification, probing pocket depth, and interproximal sites was 71.1% in predicting successful site-specific outcomes. The salivary biomarker model yielded an overall accuracy of 79.4% in predicting whole-mouth outcomes following NSPT. Conclusions: At baseline, the presence of shallow periodontal pockets at interdental locations with a lower abundance of P. gingivalis is predictive of a favorable response to NSPT at the site level. Decreased salivary MMP-9 associated with increased GST and Annexin-1 levels can predict successful whole-mouth outcomes following NSPT. Full article
(This article belongs to the Special Issue Periodontal Diseases: Clinical Diagnosis and Treatment)
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14 pages, 1887 KiB  
Article
The Influence of Cement Thickness within the Cap on Stress Distribution for Dental Implants
by Mario Ceddia, Tea Romasco, Luca Comuzzi, Alessandro Cipollina, Adriano Piattelli, Gianna Dipalma, Angelo Michele Inchingolo, Francesco Inchingolo, Natalia Di Pietro and Bartolomeo Trentadue
J. Funct. Biomater. 2024, 15(7), 199; https://doi.org/10.3390/jfb15070199 (registering DOI) - 21 Jul 2024
Abstract
The purpose of this finite element analysis (FEA) was to evaluate the stress distribution within the prosthetic components and bone in relation to varying cement thicknesses (from 20 to 60 μm) utilized to attach a zirconia crown on a conometric cap. The study [...] Read more.
The purpose of this finite element analysis (FEA) was to evaluate the stress distribution within the prosthetic components and bone in relation to varying cement thicknesses (from 20 to 60 μm) utilized to attach a zirconia crown on a conometric cap. The study focused on two types of implants (Cyroth and TAC, AoN Implants, Grisignano di Zocco, Italy) featuring a Morse cone connection. Detailed three-dimensional (3D) models were developed to represent the bone structure (cortical and trabecular) and the prosthetic components, including the crown, cement, cap, abutment, and the implant. Both implants were placed 1.5 mm subcrestally and subjected to a 200 N load at a 45° inclination on the crown. The results indicated that an increase in cement thickness led to a reduction in von Mises stress on the cortical bone for both Cyroth and TAC implants, while the decrease in stress on the trabecular bone (apical zone) was relatively less pronounced. However, the TAC implant exhibited a higher stress field in the apical area compared to the Cyroth implant. In summary, this study investigated the influence of cement thickness on stress transmission across prosthetic components and peri-implant tissues through FEA analysis, emphasizing that the 60 μm cement layer demonstrated higher stress values approaching the material strength limit. Full article
(This article belongs to the Special Issue Role of Dental Biomaterials in Promoting Oral Health)
16 pages, 5131 KiB  
Article
Exploring the Effect of Particle Loading Density on Respirable Dust Classification by SEM-EDX
by Daniel Sweeney, Cigdem Keles and Emily Sarver
Minerals 2024, 14(7), 728; https://doi.org/10.3390/min14070728 (registering DOI) - 20 Jul 2024
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Abstract
Exposure to respirable coal mine dust (RCMD) still poses health risks to miners. Scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) is a powerful tool for RCMD characterization because it provides particle-level data, including elemental ratios (via the EDX signals) that can enable [...] Read more.
Exposure to respirable coal mine dust (RCMD) still poses health risks to miners. Scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) is a powerful tool for RCMD characterization because it provides particle-level data, including elemental ratios (via the EDX signals) that can enable classification by inferred mineralogy. However, if the particle loading density (PLD) is high on the analyzed substrate (filter sample), interference between neighboring particles could cause misclassification. To investigate this possibility, a two-part study was conducted. First, the effect of PLD on RCMD classification was isolated by comparing dust particles recovered from the same parent filters under both low- and high-PLD conditions, and a set of modified classification criteria were established to correct for high PLD. Second, the modified criteria were applied to RCMD particles on pairs of filters, with each pair having one filter that was analyzed directly (frequently high PLD) and another filter from which particles were recovered and redeposited prior to analysis (frequently lower PLD). It was expected that application of the modified criteria would improve the agreement between mineralogy distributions for paired filters; however, relatively little change was observed for most pairs. These results suggest that factors other than PLD, including particle agglomeration, can have a substantial effect on the particle EDX data collected during direct-on-filter analysis. Full article
(This article belongs to the Special Issue Size Distribution, Chemical Composition and Morphology of Mine Dust)
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