Study the ratio of HDL to LDL cholesterol to determine if a person is at risk of heart attack or stroke
Study the ratio of HDL to LDL cholesterol to determine if a person is at risk of heart attack or stroke
There are two major protein complexes that transport cholesterol through the bloodstream: high-density lipoproteins (HDL) and low-density lipoproteins (LDL). Cholesterol attached to LDLs is primarily that which builds up in atherosclerotic deposits in the blood vessels; for this reason, LDL is often described as the “bad” form of cholesterol. HDLs, on the other hand, may actually serve to retard or reduce atherosclerotic buildup, and hence HDL is often referred to as the “good” form of cholesterol.
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Transcript
NARRATOR: It's common to test blood for its total cholesterol level. But blood has different specific types of cholesterol. Doctors often examine the ratio of these cholesterol types to look for warning signs.
In one such test, a test tube of plasma is spun at high speed. This causes one type of cholesterol, called low-density lipoprotein, or LDL, to separate from the high-density lipoprotein, or HDL. The HDL settles toward the bottom of the plasma sample while the LDL rises to the top. The amounts of HDL and LDL then can be measured.
A normal, healthy person may have two to three times more LDL than HDL. But if levels of LDL are higher, the person is much more likely to develop dangerous fatty deposits in their blood vessels. Such deposits may lead to heart attack or stroke.
In contrast, doctors think a lower-than-average ratio of LDL to HDL may be a good sign. They believe that HDL can reduce fatty deposits. And fewer fatty deposits mean a lower likelihood of stroke or heart attack.
In one such test, a test tube of plasma is spun at high speed. This causes one type of cholesterol, called low-density lipoprotein, or LDL, to separate from the high-density lipoprotein, or HDL. The HDL settles toward the bottom of the plasma sample while the LDL rises to the top. The amounts of HDL and LDL then can be measured.
A normal, healthy person may have two to three times more LDL than HDL. But if levels of LDL are higher, the person is much more likely to develop dangerous fatty deposits in their blood vessels. Such deposits may lead to heart attack or stroke.
In contrast, doctors think a lower-than-average ratio of LDL to HDL may be a good sign. They believe that HDL can reduce fatty deposits. And fewer fatty deposits mean a lower likelihood of stroke or heart attack.