NIHR Oxford Biomedical Research Centre

🚨 Skin patches could be used to provide an early warning of lung transplant rejection, in a new trial being funded by NIHR and the Medical Research Council . 🚨 Transplanted organs such as lungs, hearts, kidneys and pancreases are subject to attack by the immune system causing rejection. 🚨 Lung transplant rejection rates are high and limit lives. Around 55% of patients are alive after 5 years following the transplant. 🚨 Rejection is currently monitored through tests of lung function, blood tests, X-rays and biopsies. But it’s difficult to identify until it is already quite advanced. 🚨 However skin seems to reject earlier than other transplanted organs and is easily visible at all times. 🚨 Organ rejection may show as a rash on the donated skin patch, often before the body has started to reject the lungs. 🚨 Identifying the signs early allows quicker and more personalised treatment. This helps the organ to function for longer and the patient to live longer. 🚨 If the trial is successful, the researchers estimate that lung transplant rejection rates could be reduced by half. 🚨 A team from Oxford University is leading the study together with 5 UK lung transplant centres and NHS Blood and Transplant . 🚨 Read the full story at: https://lnkd.in/e8_CsPB8

https://lnkd.in/e8FGErUS #malaria #globalhealth Oxford Vaccine Group

Learn how to apply the INCLUDE ethnicity framework and increase ethnic diversity in research trials in this training video Prof Shaun Treweek, University of Aberdeen https://lnkd.in/d8rgPwvz NIHR Oxford Health Biomedical Research Centre (OH BRC) NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV)

Do you work or study at the University of Oxford and want to know more about our cancer research? Don’t miss out on this interesting seminar by Prof Tim Elliott and Prof Richard Owen, chaired by Prof Bass Hassan Nuffield Department of Medicine Radcliffe Department of Medicine, University of Oxford The Department of Biochemistry, University of Oxford Department of Biology, University of Oxford Department of Physiology, Anatomy & Genetics - University of Oxford

As part of Oxford Kafka commemorations, we are organising a special talk on the cause of Kafka’s death: #tuberculosis. Prof Helen McShane, Dr Philip Fowler and a patient representative will address the global challenge of #TB and how we are tackling it https://lnkd.in/dV4ECpHA Nuffield Department of Medicine JENNER VACCINE FOUNDATION Oxford Vaccine Group University of Oxford The Bodleian Libraries, University of Oxford Healthwatch England NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV)

A date for your diaries. Our annual Open Day with NIHR Oxford Health Biomedical Research Centre (OH BRC) will be taking place at Westgate Oxford on 30 May – a chance to find about the amazing healthcare research taking place in Oxford https://lnkd.in/dCbQiw_N NIHR (National Institute for Health and Care Research) University of Oxford Oxford University Hospitals NHS Foundation Trust NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV)

If you missed or want to watch it again…our recent public talk by Prof Eva Morris and Prof Andrea Cipriani is now available https://lnkd.in/djg8K-7A In this talk, Professor Eva Morris, Professor of Health Data Epidemiology and Oxford BRC Theme Lead for Translational Data Science, explained how harnessing data appropriately can inform NHS cancer services – and prevent hundreds of deaths every year. Professor Andrea Cipriani - Professor of Psychiatry and Director of the NIHR Oxford Health Clinical Research Facility and Oxford Health BRC Theme Lead for Data Science - discussed how clinical data can help deliver personalised care for patients with mental health disorders, improving their outcomes and reducing NHS costs. NIHR Oxford Health Biomedical Research Centre (OH BRC) University of Oxford Department of Psychiatry Big Data Institute Oxford Population Health Oxford University Hospitals NHS Foundation Trust NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV) Healthwatch England

🔔TOMORROW!! Don’t forget to attend Prof. Eva Morris & Prof. Andrea Cipriani’s talk if you want to learn how the NHS is using data to save lives https://lnkd.in/dHTzxR-6 NIHR Oxford Health Biomedical Research Centre (OH BRC) University of Oxford Department of Psychiatry Big Data Institute Oxford Population Health Oxford University Hospitals NHS Foundation Trust NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV) Healthwatch England

University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body. The clinical trial, which used the BCG vaccine delivered via aerosol into participants’ lungs, is a first step towards establishing a challenge model that can be used to test new TB vaccines. https://lnkd.in/eSkBbciA Nuffield Department of Medicine

📣 NEXT TUESDAY: Prof Eva Morris & Prof Andrea Cipriani explain how NHS data is improving cancer services & mental health care https://lnkd.in/dHTzxR-6 NIHR Oxford Health Biomedical Research Centre (OH BRC) University of Oxford Department of Psychiatry Big Data Institute Oxford Population Health Oxford University Hospitals NHS Foundation Trust NIHR CRN Thames Valley and South Midlands NIHR ARC Oxford and Thames Valley (OxTV) Healthwatch England