Children who want to change gender will no longer be prescribed puberty blockers on the NHS.
Landmark guidelines issued on Tuesday said there is not enough evidence that the drugs are safe and from now on they should only be given as part of clinical trials.
Puberty blockers suppress the release of sex hormones that cause physical changes such as breast development or the growth of facial hair. They have been prescribed to hundreds of under-16s on the NHS since 2011 at the gender identity clinic run by the Tavistock and Portman NHS Foundation Trust in north London.
A review of the Tavistock clinic in 2022 by Dr Hilary Cass warned that puberty blockers may “permanently disrupt” brain development and “lock in” children to an