New vistas on macrophage differentiation and activation.

Mantovani A; Sica A; Locati M

doi:10.1002/eji.200636910

New vistas on macrophage differentiation and activation.

Mantovani A ¹,

Sica A ,

Locati M

Affiliations

1. Istituto Clinico Humanitas, Milan, Italy.
Authors
Mantovani A¹
(1 author)

ORCIDs linked to this article

European Journal of Immunology, 01 Jan 2007, 37(1):14-16
https://doi.org/10.1002/eji.200636910 PMID: 17183610

Review

This is a comment on "Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules." Eur J Immunol. 2007 Jan;37(1):33-42. This is a comment on "Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection." Eur J Immunol. 2007 Jan;37(1):24-32.

Abstract

Plasticity and heterogeneity are hallmarks of myelomonocytic differentiation and polarized activation. Evidence published in this issue of the European Journal of Immunology, together with other recent data, add new elements and perspectives to the current understanding of mononuclear phagocyte differentiation and activation and are discussed in this Commentary.

Full text links

Read article at publisher's site: https://doi.org/10.1002/eji.200636910

References

Articles referenced by this article (23)

Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection.
Meghari S, Berruyer C, Lepidi H, Galland F, Naquet P, Mege JL
Eur J Immunol, (1):24-32 2007
MED: 17163446
Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules.
Helming L, Gordon S
Eur J Immunol, (1):33-42 2007
MED: 17154265
Alternative activation of macrophages.
Gordon S
Nat Rev Immunol, (1):23-35 2003
MED: 12511873
Monocyte and macrophage heterogeneity.
Gordon S, Taylor PR
Nat Rev Immunol, (12):953-964 2005
MED: 16322748
The chemokine system in diverse forms of macrophage activation and polarization.
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M
Trends Immunol, (12):677-686 2004
MED: 15530839
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes.
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A
Trends Immunol, (11):549-555 2002
MED: 12401408
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells.
Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, Basso G, Brombacher F, Borrello I, Zanovello P, Bicciato S, Bronte V
J Clin Invest, (10):2777-2790 2006
MED: 17016559
Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC.
Kzhyshkowska J, Workman G, Cardo-Vila M, Arap W, Pasqualini R, Gratchev A, Krusell L, Goerdt S, Sage EH
J Immunol, (10):5825-5832 2006
MED: 16670288
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.
Martinez FO, Gordon S, Locati M, Mantovani A
J Immunol, (10):7303-7311 2006
MED: 17082649
Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.
Ogawa K, Funaba M, Chen Y, Tsujimoto M
J Immunol, (10):6787-6794 2006
MED: 17082592

Show 10 more references (10 of 23)

Citations & impact

Impact metrics

232

Citations

Jump to Citations

Citations of article over time

Alternative metrics

Altmetric item for https://www.altmetric.com/details/43258690

Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/43258690

Smart citations by scite.ai
Explore citation contexts and check if this article has been supported or disputed.
https://scite.ai/reports/10.1002/eji.200636910

Supporting

Mentioning

Contrasting

327

Article citations

ROS regulation in gliomas: implications for treatment strategies.
Yang YC, Zhu Y, Sun SJ, Zhao CJ, Bai Y, Wang J, Ma LT
Front Immunol, 14:1259797, 07 Dec 2023
Cited by: 0 articles | PMID: 38130720 | PMCID: PMC10733468
Review
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
Free full text in Europe PMC
Effect of perioperative acupoint electrical stimulation on macrophages in mice under operative stress.
Zhang Y, Wei J, Wu X, Jiang M, Ma W, Li Y
J Inflamm (Lond), 20(1):29, 30 Aug 2023
Cited by: 0 articles | PMID: 37649043 | PMCID: PMC10470139
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
Free full text in Europe PMC
VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.
Alvarez-Arzola R, Bancaro N, Lai P, Attanasio G, Pellegrini L, Troiani M, Colucci M, Mosole S, Pasquini E, Alimonti A, Mesa C
Cell Commun Signal, 21(1):76, 13 Apr 2023
Cited by: 1 article | PMID: 37055829 | PMCID: PMC10100133
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
Free full text in Europe PMC
In Vitro Human Haematopoietic Stem Cell Expansion and Differentiation.
Bozhilov YK, Hsu I, Brown EJ, Wilkinson AC
Cells, 12(6):896, 14 Mar 2023
Cited by: 3 articles | PMID: 36980237 | PMCID: PMC10046976
Review
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
Free full text in Europe PMC
Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug's Efficacy and Th1 Biased Immune Response in Mesocestoides vogae (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles.
Hrčková G, Mačak Kubašková T, Mudroňová D, Jurčacková Z, Ciglanová D
Pharmaceutics, 15(2):541, 06 Feb 2023
Cited by: 0 articles | PMID: 36839863 | PMCID: PMC9962889
Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted under certain circumstances. There are six different Creative Commons licenses available, see the copyright license for this article to understand what type of reuse is permitted.
Free full text in Europe PMC

Go to all (232) article citations

Search life-sciences literature (44,004,653 articles, preprints and more)

New vistas on macrophage differentiation and activation.

Affiliations

Authors

ORCIDs linked to this article

Abstract

Full text links

References

Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection.

Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules.

Alternative activation of macrophages.

Monocyte and macrophage heterogeneity.

The chemokine system in diverse forms of macrophage activation and polarization.

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes.

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells.

Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC.

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.

Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Smart citations by scite.ai
Explore citation contexts and check if this article has been supported or disputed.
https://scite.ai/reports/10.1002/eji.200636910

Article citations

ROS regulation in gliomas: implications for treatment strategies.

Effect of perioperative acupoint electrical stimulation on macrophages in mice under operative stress.

VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.

In Vitro Human Haematopoietic Stem Cell Expansion and Differentiation.

Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug's Efficacy and Th1 Biased Immune Response in Mesocestoides vogae (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles.

Similar Articles

From phagocyte diversity and activation to probiotics: back to Metchnikoff.

PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.

SOCS proteins, cytokine signalling and immune regulation.

p21(waf1/CIP1), a CDK inhibitor and a negative feedback system that controls macrophage activation.

Alternative macrophage activation in periprosthetic osteolysis.

Similar Articles

From phagocyte diversity and activation to probiotics: back to Metchnikoff.
Eur J Immunol, 38(12):3269-3273, 01 Dec 2008

PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.
Eur J Immunol, 37(5):1343-1354, 01 May 2007

SOCS proteins, cytokine signalling and immune regulation.
Nat Rev Immunol, 7(6):454-465, 18 May 2007

p21(waf1/CIP1), a CDK inhibitor and a negative feedback system that controls macrophage activation.
Eur J Immunol, 39(3):691-694, 01 Mar 2009

Alternative macrophage activation in periprosthetic osteolysis.
Autoimmunity, 41(3):212-217, 01 Apr 2008

Search life-sciences literature (44,004,653 articles, preprints and more)

New vistas on macrophage differentiation and activation.

Author information

Affiliations

Authors

ORCIDs linked to this article

Abstract

Full text links

References

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Article citations

Similar Articles